A previously healthy girl aged 3 years presented to the hospital with fever, vomiting and refusal to walk of 3 days’ duration. The physical examination revealed oropharyngeal hyperaemia and tenderness on palpation in the right elbow and leg. A strep test was performed (which turned positive), along with routine blood tests and a blood culture. After 12 hours, she developed erythema and swelling in the right leg and foot (Fig. 1), very tender to the touch.
On account of suggestive features in the local MRI scan (Fig. 2), a working diagnosis of necrotising fasciitis was made, which called for urgent surgical debridement and intravenous antibiotherapy. The intraoperative wound and blood cultures were positive for Streptococcus pyogenes.
On day 5, the patient developed pain in the right elbow and left shoulder (Fig. 3) and the fever recurred. A whole-body MRI was ordered, with visualization of features compatible with multifocal necrotising fasciitis (Fig. 3b), and calling for additional debridement. The histological examination revealed necrosis of the superficial muscular fascia.
Necrotising fasciitis is a disease resulting from invasive infection by S pyogenes that causes necrosis of the muscular fascia and a systemic inflammatory response.1 It manifests with fever, general malaise and local pain that appears disproportionate in relation to the cutaneous findings.1 It is a clinical diagnosis, and imaging tests, such as MRI, can be useful.1 Multifocal forms are rare2 and thereby pose a diagnostic challenge. Early surgical debridement and initiation of intravenous antibiotherapy with penicillin and clindamycin1,2 are essential to reduce the associated morbidity and mortality.3
FundingThis research did not receive any external funding.
Conflicts of interestThe authors have no conflicts of interest to declare.
Previous meeting: Presented at the Meeting of the Working Group on Emergency Medicine of the Sociedad Catalana de Pediatría, March 8, 2023, Barcelona, Spain. Also at the Congress of the Sociedad Catalana de Pediatría, June 8, 2023, Reus, Spain.