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        "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Evaluar los hallazgos de la gammagraf&#237;a renal &#40;DMSA&#41; en ni&#241;os con una primera infecci&#243;n del tracto urinario &#40;ITU&#41; febril en relaci&#243;n con diversos par&#225;metros cl&#237;nico-biol&#243;gicos y otros estudios de imagen y seguimiento a largo plazo&#46;</p> <span class="elsevierStyleSectionTitle">Material y m&#233;todos</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">En un grupo de 103 pacientes &#40;con edades comprendidas entre un mes y 10 a&#241;os&#41; con una primera ITU febril&#44; se han evaluado par&#225;metros cl&#237;nicos&#44; anal&#237;ticos y pruebas de imagen en la fase aguda de la enfermedad&#46; Los pacientes se dividieron en dos grupos de edad&#44; menores &#40;n &#61; 63&#41; y mayores de 2 a&#241;os &#40;n &#61; 40&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">La gammagraf&#237;a fue patol&#243;gica en el 54&#44;5&#37; del grupo total&#44; en el 39&#44;7&#37; en menores de 2 a&#241;os y en el 79&#44;5&#37; de los mayores de 2 a&#241;os&#46; En la ecograf&#237;a con medici&#243;n del volumen renal se detect&#243; una concordancia simple con la gammagraf&#237;a en el 64&#37; de los casos&#46; La cistograf&#237;a objetiv&#243; un reflujo en el 22&#44;3&#37; de los pacientes&#44; sin encontrar diferencias estad&#237;sticamente significativas entre los que presentaron un DMSA normal o patol&#243;gico&#46; Al estudiar los factores que se asociaron de forma independiente a un resultado patol&#243;gico en el DMSA mediante un an&#225;lisis multivariante de regresi&#243;n log&#237;stica&#44; se observ&#243; que la edad del ni&#241;o&#44; la elevaci&#243;n de la prote&#237;na C reactiva &#40;PCR&#41; y la alteraci&#243;n del volumen renal resultaron asociarse de forma estad&#237;sticamente significativa a una mayor presencia de DMSA patol&#243;gico&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">El DMSA combinado con otras pruebas diagn&#243;sticas puede mejorar la sensibilidad y especificidad para establecer el grado de afectaci&#243;n renal&#46; Durante el seguimiento&#44; las lesiones agudas desaparecen o mejoran en todos los casos y las cr&#243;nicas no se modifican&#46;</p>"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">The objective of this study was to evaluate the findings of <span class="elsevierStyleSup">99m</span>Tc-DMSA renal scintigraphy in children with their first acute febrile urinary tract infection in relation with several clinical-biological parameters and other imaging studies and a long-term follow up&#46;</p> <span class="elsevierStyleSectionTitle">Material and methods</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">103 children between 1 month and 10 years old with their first acute febrile urinary tract infection were studied by means of clinical and laboratory assesment&#44; renal ultrasonography and <span class="elsevierStyleSup">99m</span>Tc DMSA renal scintigraphy in the acute illness period&#46; Patients were divided into two groups&#44; those under 2 years old &#40;n &#61; 63&#41; and those over 2 years old &#40;n &#61; 40&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Cortical scintigraphy showed renal changes in 56 patients &#40;54&#44;5&#37;&#41;&#46; Children over 2 years of age had a higher incidence of renal lesions than younger children &#40;39&#44;7&#37; vs 77&#44;5&#37;&#41;&#46; Ultrasonography measuring renal volume showed a simple concordance with scintigraphy in 64&#37; of the patients&#46; Reflux was demonstrated in 23 patients &#40;22&#44;3&#37;&#41; without differences between patients with normal or abnormal cortical scintigraphy&#46; After having studied the factors that were associated independently to the pathological results in the scintigraphy through a logistical multivariant regression&#44; it was observed that the child&#8217;s age&#44; the elevation of the PCR and the alterations of the renal volume were significant according to statistics and also associated to a larger amount of pathological DMSA scintigraphy&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">DMSA scintigraphy associated with other diagnostic methods can improve the sensitivity and specificity to es tablish renal damage stage&#46; During the follow-up the acute lesions disapeared or improved in all cases and the chronic lesions have not been modificated&#46;</p>"
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Vol. 52. Núm. 1.
Páginas 23-30 (enero 1999)
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Vol. 52. Núm. 1.
Páginas 23-30 (enero 1999)
Acceso a texto completo
Gammagrafía con tecnecio-99m-ácido dimercaptosuccínico en el estudio de la primera infección urinaria febril del niño
Technetium-99m-dimercaptosuccinic acid (dmsa) scintigraphy in febrile firsttime urinary tract infection in children
Visitas
13211
M.J. Martín Aguado*,*, A. Canals Baeza*, J. Vioque López**, J.L. Tarazona*, J. Flores Serrano*
* Servicio de Pediatría. Hospital General Universitario de Alicante.
** Departamento de Salud Pública. Facultad de Medicina. Universidad Miguel Hernández. Elche. Alicante
Este artículo ha recibido
Información del artículo
Objetivo

Evaluar los hallazgos de la gammagrafía renal (DMSA) en niños con una primera infección del tracto urinario (ITU) febril en relación con diversos parámetros clínico-biológicos y otros estudios de imagen y seguimiento a largo plazo.

Material y métodos

En un grupo de 103 pacientes (con edades comprendidas entre un mes y 10 años) con una primera ITU febril, se han evaluado parámetros clínicos, analíticos y pruebas de imagen en la fase aguda de la enfermedad. Los pacientes se dividieron en dos grupos de edad, menores (n = 63) y mayores de 2 años (n = 40).

Resultados

La gammagrafía fue patológica en el 54,5% del grupo total, en el 39,7% en menores de 2 años y en el 79,5% de los mayores de 2 años. En la ecografía con medición del volumen renal se detectó una concordancia simple con la gammagrafía en el 64% de los casos. La cistografía objetivó un reflujo en el 22,3% de los pacientes, sin encontrar diferencias estadísticamente significativas entre los que presentaron un DMSA normal o patológico. Al estudiar los factores que se asociaron de forma independiente a un resultado patológico en el DMSA mediante un análisis multivariante de regresión logística, se observó que la edad del niño, la elevación de la proteína C reactiva (PCR) y la alteración del volumen renal resultaron asociarse de forma estadísticamente significativa a una mayor presencia de DMSA patológico.

Conclusiones

El DMSA combinado con otras pruebas diagnósticas puede mejorar la sensibilidad y especificidad para establecer el grado de afectación renal. Durante el seguimiento, las lesiones agudas desaparecen o mejoran en todos los casos y las crónicas no se modifican.

Palabras clave:
Infección urinaria
Pielonefritis aguda
Gammagrafía con 99mTc-DMSA
Ecografía renal
Reflujo vesicoureteral
Objective

The objective of this study was to evaluate the findings of 99mTc-DMSA renal scintigraphy in children with their first acute febrile urinary tract infection in relation with several clinical-biological parameters and other imaging studies and a long-term follow up.

Material and methods

103 children between 1 month and 10 years old with their first acute febrile urinary tract infection were studied by means of clinical and laboratory assesment, renal ultrasonography and 99mTc DMSA renal scintigraphy in the acute illness period. Patients were divided into two groups, those under 2 years old (n = 63) and those over 2 years old (n = 40).

Results

Cortical scintigraphy showed renal changes in 56 patients (54,5%). Children over 2 years of age had a higher incidence of renal lesions than younger children (39,7% vs 77,5%). Ultrasonography measuring renal volume showed a simple concordance with scintigraphy in 64% of the patients. Reflux was demonstrated in 23 patients (22,3%) without differences between patients with normal or abnormal cortical scintigraphy. After having studied the factors that were associated independently to the pathological results in the scintigraphy through a logistical multivariant regression, it was observed that the child’s age, the elevation of the PCR and the alterations of the renal volume were significant according to statistics and also associated to a larger amount of pathological DMSA scintigraphy.

Conclusions

DMSA scintigraphy associated with other diagnostic methods can improve the sensitivity and specificity to es tablish renal damage stage. During the follow-up the acute lesions disapeared or improved in all cases and the chronic lesions have not been modificated.

Key words:
Urinary tract infection
Acute pyelonephritis
Renal scintigraphy-DMSA
Renal ultrasonography
Vesicoureteral reflux
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