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        "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Evaluar los hallazgos de la gammagraf&#237;a renal &#40;DMSA&#41; en ni&#241;os con una primera infecci&#243;n del tracto urinario &#40;ITU&#41; febril en relaci&#243;n con diversos par&#225;metros cl&#237;nico-biol&#243;gicos y otros estudios de imagen y seguimiento a largo plazo&#46;</p> <span class="elsevierStyleSectionTitle">Material y m&#233;todos</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">En un grupo de 103 pacientes &#40;con edades comprendidas entre un mes y 10 a&#241;os&#41; con una primera ITU febril&#44; se han evaluado par&#225;metros cl&#237;nicos&#44; anal&#237;ticos y pruebas de imagen en la fase aguda de la enfermedad&#46; Los pacientes se dividieron en dos grupos de edad&#44; menores &#40;n &#61; 63&#41; y mayores de 2 a&#241;os &#40;n &#61; 40&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">La gammagraf&#237;a fue patol&#243;gica en el 54&#44;5&#37; del grupo total&#44; en el 39&#44;7&#37; en menores de 2 a&#241;os y en el 79&#44;5&#37; de los mayores de 2 a&#241;os&#46; En la ecograf&#237;a con medici&#243;n del volumen renal se detect&#243; una concordancia simple con la gammagraf&#237;a en el 64&#37; de los casos&#46; La cistograf&#237;a objetiv&#243; un reflujo en el 22&#44;3&#37; de los pacientes&#44; sin encontrar diferencias estad&#237;sticamente significativas entre los que presentaron un DMSA normal o patol&#243;gico&#46; Al estudiar los factores que se asociaron de forma independiente a un resultado patol&#243;gico en el DMSA mediante un an&#225;lisis multivariante de regresi&#243;n log&#237;stica&#44; se observ&#243; que la edad del ni&#241;o&#44; la elevaci&#243;n de la prote&#237;na C reactiva &#40;PCR&#41; y la alteraci&#243;n del volumen renal resultaron asociarse de forma estad&#237;sticamente significativa a una mayor presencia de DMSA patol&#243;gico&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">El DMSA combinado con otras pruebas diagn&#243;sticas puede mejorar la sensibilidad y especificidad para establecer el grado de afectaci&#243;n renal&#46; Durante el seguimiento&#44; las lesiones agudas desaparecen o mejoran en todos los casos y las cr&#243;nicas no se modifican&#46;</p>"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">The objective of this study was to evaluate the findings of <span class="elsevierStyleSup">99m</span>Tc-DMSA renal scintigraphy in children with their first acute febrile urinary tract infection in relation with several clinical-biological parameters and other imaging studies and a long-term follow up&#46;</p> <span class="elsevierStyleSectionTitle">Material and methods</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">103 children between 1 month and 10 years old with their first acute febrile urinary tract infection were studied by means of clinical and laboratory assesment&#44; renal ultrasonography and <span class="elsevierStyleSup">99m</span>Tc DMSA renal scintigraphy in the acute illness period&#46; Patients were divided into two groups&#44; those under 2 years old &#40;n &#61; 63&#41; and those over 2 years old &#40;n &#61; 40&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Cortical scintigraphy showed renal changes in 56 patients &#40;54&#44;5&#37;&#41;&#46; Children over 2 years of age had a higher incidence of renal lesions than younger children &#40;39&#44;7&#37; vs 77&#44;5&#37;&#41;&#46; Ultrasonography measuring renal volume showed a simple concordance with scintigraphy in 64&#37; of the patients&#46; Reflux was demonstrated in 23 patients &#40;22&#44;3&#37;&#41; without differences between patients with normal or abnormal cortical scintigraphy&#46; After having studied the factors that were associated independently to the pathological results in the scintigraphy through a logistical multivariant regression&#44; it was observed that the child&#8217;s age&#44; the elevation of the PCR and the alterations of the renal volume were significant according to statistics and also associated to a larger amount of pathological DMSA scintigraphy&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">DMSA scintigraphy associated with other diagnostic methods can improve the sensitivity and specificity to es tablish renal damage stage&#46; During the follow-up the acute lesions disapeared or improved in all cases and the chronic lesions have not been modificated&#46;</p>"
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Gammagrafía con tecnecio-99m-ácido dimercaptosuccínico en el estudio de la primera infección urinaria febril del niño
Technetium-99m-dimercaptosuccinic acid (dmsa) scintigraphy in febrile firsttime urinary tract infection in children
M.J. Martín Aguado*,*, A. Canals Baeza*, J. Vioque López**, J.L. Tarazona*, J. Flores Serrano*
* Servicio de Pediatría. Hospital General Universitario de Alicante.
** Departamento de Salud Pública. Facultad de Medicina. Universidad Miguel Hernández. Elche. Alicante
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        "titulo" => "Technetium-99m-dimercaptosuccinic acid &#40;dmsa&#41; scintigraphy in febrile firsttime urinary tract infection in children"
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            0 => "Urinary tract infection"
            1 => "Acute pyelonephritis"
            2 => "Renal scintigraphy-DMSA"
            3 => "Renal ultrasonography"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Evaluar los hallazgos de la gammagraf&#237;a renal &#40;DMSA&#41; en ni&#241;os con una primera infecci&#243;n del tracto urinario &#40;ITU&#41; febril en relaci&#243;n con diversos par&#225;metros cl&#237;nico-biol&#243;gicos y otros estudios de imagen y seguimiento a largo plazo&#46;</p> <span class="elsevierStyleSectionTitle">Material y m&#233;todos</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">En un grupo de 103 pacientes &#40;con edades comprendidas entre un mes y 10 a&#241;os&#41; con una primera ITU febril&#44; se han evaluado par&#225;metros cl&#237;nicos&#44; anal&#237;ticos y pruebas de imagen en la fase aguda de la enfermedad&#46; Los pacientes se dividieron en dos grupos de edad&#44; menores &#40;n &#61; 63&#41; y mayores de 2 a&#241;os &#40;n &#61; 40&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">La gammagraf&#237;a fue patol&#243;gica en el 54&#44;5&#37; del grupo total&#44; en el 39&#44;7&#37; en menores de 2 a&#241;os y en el 79&#44;5&#37; de los mayores de 2 a&#241;os&#46; En la ecograf&#237;a con medici&#243;n del volumen renal se detect&#243; una concordancia simple con la gammagraf&#237;a en el 64&#37; de los casos&#46; La cistograf&#237;a objetiv&#243; un reflujo en el 22&#44;3&#37; de los pacientes&#44; sin encontrar diferencias estad&#237;sticamente significativas entre los que presentaron un DMSA normal o patol&#243;gico&#46; Al estudiar los factores que se asociaron de forma independiente a un resultado patol&#243;gico en el DMSA mediante un an&#225;lisis multivariante de regresi&#243;n log&#237;stica&#44; se observ&#243; que la edad del ni&#241;o&#44; la elevaci&#243;n de la prote&#237;na C reactiva &#40;PCR&#41; y la alteraci&#243;n del volumen renal resultaron asociarse de forma estad&#237;sticamente significativa a una mayor presencia de DMSA patol&#243;gico&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">El DMSA combinado con otras pruebas diagn&#243;sticas puede mejorar la sensibilidad y especificidad para establecer el grado de afectaci&#243;n renal&#46; Durante el seguimiento&#44; las lesiones agudas desaparecen o mejoran en todos los casos y las cr&#243;nicas no se modifican&#46;</p>"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">The objective of this study was to evaluate the findings of <span class="elsevierStyleSup">99m</span>Tc-DMSA renal scintigraphy in children with their first acute febrile urinary tract infection in relation with several clinical-biological parameters and other imaging studies and a long-term follow up&#46;</p> <span class="elsevierStyleSectionTitle">Material and methods</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">103 children between 1 month and 10 years old with their first acute febrile urinary tract infection were studied by means of clinical and laboratory assesment&#44; renal ultrasonography and <span class="elsevierStyleSup">99m</span>Tc DMSA renal scintigraphy in the acute illness period&#46; Patients were divided into two groups&#44; those under 2 years old &#40;n &#61; 63&#41; and those over 2 years old &#40;n &#61; 40&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Cortical scintigraphy showed renal changes in 56 patients &#40;54&#44;5&#37;&#41;&#46; Children over 2 years of age had a higher incidence of renal lesions than younger children &#40;39&#44;7&#37; vs 77&#44;5&#37;&#41;&#46; Ultrasonography measuring renal volume showed a simple concordance with scintigraphy in 64&#37; of the patients&#46; Reflux was demonstrated in 23 patients &#40;22&#44;3&#37;&#41; without differences between patients with normal or abnormal cortical scintigraphy&#46; After having studied the factors that were associated independently to the pathological results in the scintigraphy through a logistical multivariant regression&#44; it was observed that the child&#8217;s age&#44; the elevation of the PCR and the alterations of the renal volume were significant according to statistics and also associated to a larger amount of pathological DMSA scintigraphy&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">DMSA scintigraphy associated with other diagnostic methods can improve the sensitivity and specificity to es tablish renal damage stage&#46; During the follow-up the acute lesions disapeared or improved in all cases and the chronic lesions have not been modificated&#46;</p>"
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ISSN: 16954033
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