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        "resumen" => "<span class="elsevierStyleSectionTitle">Objetivos</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Describir la incidencia de hospitalizaci&#243;n por bronquiolitis en los reci&#233;n nacidos de nuestra poblaci&#243;n&#44; analizar las repercusiones de la prematuridad y la enfermedad perinatal sobre la hospitalizaci&#243;n de estos pacientes&#44; y comparar los resultados con los obtenidos en el Impact-RSV Study Group&#46;</p> <span class="elsevierStyleSectionTitle">Material y m&#233;todos</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Estudio descriptivo por revisi&#243;n de historias cl&#237;nicas&#46; Se han estudiado las caracter&#237;sticas perinatales de todos los reci&#233;n nacidos y de los pacientes hospitalizados por bronquiolitis durante un per&#237;odo de 3 a&#241;os&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">De 12&#46;895 reci&#233;n nacidos precisaron hospitalizaci&#243;n por bronquiolitis 455 pacientes &#40;3&#44;52&#37;&#41;&#46; Fueron hospitalizados por bronquiolitis el 3&#44;18&#37; de los reci&#233;n nacidos a t&#233;rmino&#44; el 8&#44;6&#37; de los pret&#233;rmino&#44; el 9&#44;8&#37; de los que presentaban cardiopat&#237;a cong&#233;nita y el 21&#44;1 &#37; de los prematuros que necesitaron ventilaci&#243;n mec&#225;nica durante el per&#237;odo neonatal&#46; Los factores de riesgo relacionados con el ingreso en la Unidad de Cuidados Intensivos &#40;UCI&#41; fueron la edad posnatal inferior a 6 semanas &#40;OR&#44; 1&#44;68&#59; intervalo de confianza &#91;IC&#93; del 95&#37;&#44; 1&#44;&#8211;8&#44;19&#59; p &#61; 0&#44;04&#41; y la prematuridad &#40;OR&#44; 2&#44;67&#59; IC 95&#37;&#44; 1&#44;&#8211;7&#44;56&#59; p &#61; 0&#44;006&#41;&#46; La hospitalizaci&#243;n por bronquiolitis por virus respiratorio sincitial &#40;VRS&#41; positivo es el 40 &#37; inferior a la del Impact-RSV Study Group&#46; Si se excluyen los reci&#233;n nacidos con displasia broncopulmonar&#44; cardiopat&#237;a cong&#233;nita y ventilaci&#243;n mec&#225;nica neonatal&#44; el porcentaje de ingresos VRS &#40;&#43;&#41; en reci&#233;n nacidos menores de 32 semanas de gestaci&#243;n es similar al de los nacidos entre las 32 y 35 semanas de gestaci&#243;n &#40;3&#44;4 frente a 4&#44;3&#37;&#44; p &#62; 0&#44;10&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">La ventilaci&#243;n mec&#225;nica neonatal&#44; la displasia broncopulmonar y la cardiopat&#237;a cong&#233;nita repercuten en el ingreso hospitalario y en la estancia media por bronquiolitis VRS &#40;&#43; &#41; m&#225;s que la edad gestacional de los reci&#233;n nacidos</p>"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Objectives</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">To describe the rate of hospitalization for bronchiolitis among newborn infants in our environment&#44; to evaluate the influence of prematurity and other perinatal conditions on hospitalization for bronchiolitis&#44; and to compare our data with those of the Impact-RSV Study Group&#46;</p> <span class="elsevierStyleSectionTitle">Method</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Descriptive studying based on analysis of the perinatal data of all neonates and patients hospitalized for bronchiolitis during a 3-year period</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Among 12&#44;895 newborn infants&#44; 455 &#40;3&#46;52 &#37;&#41; required hospitalization for bronchiolitis&#46; The hospitalization rate for bronchiolitis was 3&#46;18&#37; among term infants&#44; 8&#46;6&#37; among preterm infants&#44; 9&#46;8&#37; among infants with congenital heart disease and 21&#46;1 &#37; among preterm infants who required mechanical ventilation during the neonatal period&#46; Intensive care unit admission was associated with postnatal age under 6 weeks &#40;OR&#58; 1&#46;68&#59; 95 &#37; CI&#58; &#8211;8&#46;19&#59; p &#61; 0&#46;04&#41; and prematurity &#40;OR&#58; 2&#44;67&#59; 95&#37; CI&#58; &#8211;7&#46;56&#59; p &#61; 0&#46;006&#41;&#46; The hospitalization rate for bronchiolitis was 40 &#37; lower in our neonatal population than in that of the Impact-RSV Study Group&#46; When infants with bronchopulmonary dysplasia&#44; congenital heart disease and mechanical ventilation during the neonatal period were excluded&#44; the hospitalization rate for respiratory syncytial virus &#40;RSV&#41; was not significantly different between infants born at &#60; 32 weeks&#39; gestation and those born at &#8211;35 weeks&#39; gestation &#40;3&#46;4&#37; vs 4&#46;3&#37;&#59; p &#62; 0&#46;10&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Neonatal mechanical ventilation&#44; bronchopulmonary dysplasia and congenital heart disease are more closely associated with hospitalization for RSV&#40;&#43; &#41; bronchiolitis and mean length of stay than with gestational age</p>"
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Vol. 53. Núm. 6.
Páginas 527-532 (diciembre 2000)
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Vol. 53. Núm. 6.
Páginas 527-532 (diciembre 2000)
Acceso a texto completo
Antecedentes perinatales y hospitalización por bronquiolitis. Comparación con el Impact-RSV Study Group
Perinatal antecedents associated with hospitalization for bronchiolitis. a comparison with the impact-rsv study group
Visitas
17598
A. Bonillo Peralesa,
Autor para correspondencia
abonillop@wanadoo.es

Unidad de Cuidados Intensivos Pediátrica. Hospital Torrecárdenas. Paraje Torrecárdenas, s/n. 04009 Almería
, J. Díez-Delgado Rubioa, A. Ortega Montesa, P. Infante Márquezb, M.R. Jiménez Liriaa, J. Batlles Garridoa, J. López Muñoza
a Servicios de Pediatría. Hospital Torrecárdenas
b Servicios de Pediatría. Hospital Poniente. Almería
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Estadísticas
Objetivos

Describir la incidencia de hospitalización por bronquiolitis en los recién nacidos de nuestra población, analizar las repercusiones de la prematuridad y la enfermedad perinatal sobre la hospitalización de estos pacientes, y comparar los resultados con los obtenidos en el Impact-RSV Study Group.

Material y métodos

Estudio descriptivo por revisión de historias clínicas. Se han estudiado las características perinatales de todos los recién nacidos y de los pacientes hospitalizados por bronquiolitis durante un período de 3 años.

Resultados

De 12.895 recién nacidos precisaron hospitalización por bronquiolitis 455 pacientes (3,52%). Fueron hospitalizados por bronquiolitis el 3,18% de los recién nacidos a término, el 8,6% de los pretérmino, el 9,8% de los que presentaban cardiopatía congénita y el 21,1 % de los prematuros que necesitaron ventilación mecánica durante el período neonatal. Los factores de riesgo relacionados con el ingreso en la Unidad de Cuidados Intensivos (UCI) fueron la edad posnatal inferior a 6 semanas (OR, 1,68; intervalo de confianza [IC] del 95%, 1,–8,19; p = 0,04) y la prematuridad (OR, 2,67; IC 95%, 1,–7,56; p = 0,006). La hospitalización por bronquiolitis por virus respiratorio sincitial (VRS) positivo es el 40 % inferior a la del Impact-RSV Study Group. Si se excluyen los recién nacidos con displasia broncopulmonar, cardiopatía congénita y ventilación mecánica neonatal, el porcentaje de ingresos VRS (+) en recién nacidos menores de 32 semanas de gestación es similar al de los nacidos entre las 32 y 35 semanas de gestación (3,4 frente a 4,3%, p > 0,10).

Conclusiones

La ventilación mecánica neonatal, la displasia broncopulmonar y la cardiopatía congénita repercuten en el ingreso hospitalario y en la estancia media por bronquiolitis VRS (+ ) más que la edad gestacional de los recién nacidos

Palabras clave:
Virus respiratorio sincitial
Bronquiolitis
Hospitalización
Profilaxis
Prematuridad
Niños
Objectives

To describe the rate of hospitalization for bronchiolitis among newborn infants in our environment, to evaluate the influence of prematurity and other perinatal conditions on hospitalization for bronchiolitis, and to compare our data with those of the Impact-RSV Study Group.

Method

Descriptive studying based on analysis of the perinatal data of all neonates and patients hospitalized for bronchiolitis during a 3-year period

Results

Among 12,895 newborn infants, 455 (3.52 %) required hospitalization for bronchiolitis. The hospitalization rate for bronchiolitis was 3.18% among term infants, 8.6% among preterm infants, 9.8% among infants with congenital heart disease and 21.1 % among preterm infants who required mechanical ventilation during the neonatal period. Intensive care unit admission was associated with postnatal age under 6 weeks (OR: 1.68; 95 % CI: –8.19; p = 0.04) and prematurity (OR: 2,67; 95% CI: –7.56; p = 0.006). The hospitalization rate for bronchiolitis was 40 % lower in our neonatal population than in that of the Impact-RSV Study Group. When infants with bronchopulmonary dysplasia, congenital heart disease and mechanical ventilation during the neonatal period were excluded, the hospitalization rate for respiratory syncytial virus (RSV) was not significantly different between infants born at < 32 weeks' gestation and those born at –35 weeks' gestation (3.4% vs 4.3%; p > 0.10).

Conclusions

Neonatal mechanical ventilation, bronchopulmonary dysplasia and congenital heart disease are more closely associated with hospitalization for RSV(+ ) bronchiolitis and mean length of stay than with gestational age

Keywords:
Respiratory syncytial virus
Bronchiolitis
Hospitalisation
Prophylaxis
Prematurity Infants
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