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                      "titulo" => "Idiopathic acute interstitial nephritis&#58; characterization of the infiltrating cells in the renal interstitium as T helper lymphocytes"
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                          "etal" => false
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                        "tituloSerie" => "Am J Kidney Dis"
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                        "paginaInicial" => "24"
                        "paginaFinal" => "29"
                        "link" => array:1 [
                          0 => array:2 [
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                          "autores" => array:1 [
                            0 => "W&#46;T&#46; Councilman"
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                      "Revista" => array:5 [
                        "tituloSerie" => "J Exp Med"
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                        "volumen" => "1898"
                        "paginaInicial" => "393"
                        "paginaFinal" => "420"
                      ]
                    ]
                  ]
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                      "titulo" => "Acute tubulointerstitial nephritis associated with Yersinia pseudotuberculosis infection"
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                          "etal" => false
                          "autores" => array:6 [
                            0 => "K&#46; Okada"
                            1 => "I&#46; Yano"
                            2 => "S&#46; Kagami"
                            3 => "M&#46; Funai"
                            4 => "S&#46; Kawahito"
                            5 => "T&#46; Okamoto"
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                        ]
                      ]
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                  ]
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                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Clin Nephrol"
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                        "paginaInicial" => "105"
                        "paginaFinal" => "109"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2032394"
                            "web" => "Medline"
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                      "titulo" => "Nefritis intersticial aguda asociada a infecci&#243;n estreptoc&#243;cica"
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                          "etal" => false
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                        "paginaFinal" => "278"
                        "link" => array:1 [
                          0 => array:2 [
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                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Kidney Dis"
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                        "paginaInicial" => "76"
                        "paginaFinal" => "77"
                        "link" => array:1 [
                          0 => array:2 [
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                        "paginaFinal" => "511"
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                        "paginaFinal" => "591"
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                        "paginaFinal" => "333"
                        "link" => array:1 [
                          0 => array:2 [
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                            2 => "E&#46;J&#46; Yunis"
                            3 => "E&#46;B&#46; Blau"
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                      ]
                    ]
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                  "host" => array:1 [
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                        "paginaInicial" => "862"
                        "paginaFinal" => "870"
                        "link" => array:1 [
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                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7015263"
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                0 => array:2 [
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                    0 => array:2 [
                      "titulo" => "Acute interstitial nephritis presenting as presumed minimal change nephritic syndrome"
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                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
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                        "tituloSerie" => "Pediatr Nephrol"
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                        "paginaInicial" => "576"
                        "paginaFinal" => "578"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9761358"
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Vol. 52. Núm. 3.
Páginas 275-278 (marzo 2000)
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Vol. 52. Núm. 3.
Páginas 275-278 (marzo 2000)
Acceso a texto completo
Nefritis intersticial aguda de probable etiología medicamentosa
Acute Interstitial Nephritis Of Probable Pharmacological Origin
Visitas
21768
A. Giménez Llort*, J. Villanueva Lamas, J. Ros Viladoms, A. Colet Llansana, A.M. Plaza Martín, V. Cusí Sánchez, A. Camacho Díaz
Unidad Integrada de Pediatría. Hospital Clínic-Sant Joan de Dèu-Casa Maternitat. Universidad de Barcelona
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Información del artículo

La nefritis intersticial aguda es una entidad rara en los niños. Presentamos un caso de nefritis intersticial aguda cuya etiología probablemente sea medicamentosa en un paciente de 10 años de edad. Presentaba fiebre, astenia,pérdida de peso, alteraciones en análisis de orina e insuficiencia renal leve. Se realizó tratamiento con corticoides obteniéndose una buena respuesta con mejoría clínica y normalización de la función renal al cabo de pocos meses.

Palabras clave:
Nefritis intersticial aguda
Toxicidad medicamentosa
Infancia

Acute interstitial nephritis in children is rare. We present a case of acute interstitial nephritis in a 10-year-old boy, which was probably drug-induced. Initial symptoms included fever, loss of appetite, weight loss, alterations in urine analysis and mild renal failure. Treatment with steroids produced a good clinical response and renal function returned to normal within a few months.

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Bibliografía
[1.]
R. Pamukcu, A.V. Moorthy, J.R. Singer, R. Hong, D.P. Simpson.
Idiopathic acute interstitial nephritis: characterization of the infiltrating cells in the renal interstitium as T helper lymphocytes.
Am J Kidney Dis, 4 (1984), pp. 24-29
[2.]
W.T. Councilman.
Acute intertitial nephritis.
J Exp Med, 1898 (1991), pp. 393-420
[3.]
K. Okada, I. Yano, S. Kagami, M. Funai, S. Kawahito, T. Okamoto.
Acute tubulointerstitial nephritis associated with Yersinia pseudotuberculosis infection.
Clin Nephrol, 35 (1991), pp. 105-109
[4.]
E. Martín Hernández, J. Millán Otegui, A. Bueno Fernández, M. Peña Muñoz, A. Martínez Valverde.
Nefritis intersticial aguda asociada a infección estreptocócica.
An Esp Pediatr, 35 (1991), pp. 276-278
[5.]
J. Koplovic, G. Pinkus, S. Rosen.
Interstitial nephritis in infections mononucleosis.
Am J Kidney Dis, 12 (1988), pp. 76-77
[6.]
G.B. Appel, G. Garvey, F. Silva, E. Francke, H.C. Neu, J. Weissman.
Acute interstitial nephritis due to amoxicillin therapy.
Nephron, 27 (1981), pp. 313-315
[7.]
J.P. Tolins, P. Seel.
Ibuprofen induced interstitial nephritis and the nephrotic syndrome.
Minn Med, 70 (1987), pp. 509-511
[8.]
S. Gómez García, F. Conde Redondo, J.J. Mateos Otero.
Nefritis intersticial con uveítis.
An Esp Pediatr, 33 (1990), pp. 589-591
[9.]
A. Boucher, D. Droz, E. Adafer, L.H. Noël.
Characterization of mononuclear cell subsets in renal cellular interstitial infiltrates.
Kidney Int, 29 (1986), pp. 1043-1049
[10.]
J. Bergstein, N. Litman.
Interstitial nephritis with antitubular basement membrane antibody.
N Engl J Med, 292 (1975), pp. 875-878
[11.]
R.S. Dobrin, R.L. Vernier, A.J. Fish.
Acute eosinophilic interstitial nephritis and renal failure with bone marrowlymph node granulomas and anterior uveitis.
Am J Med, 59 (1975), pp. 325-333
[12.]
B.S. Ooi, M.R. First, A.J. Pesce, V.E. Pollack.
IgE levels in interstitial nephritis.
Lancet, 1 (1974), pp. 1254-1256
[13.]
D. Ellis, W.A. Fried, E.J. Yunis, E.B. Blau.
Acute interstitial nephritis in children. A report of 13 cases and review ot the literature.
Pediatrics, 67 (1981), pp. 862-870
[14.]
V.R. Dharnidharka, S. Rosen, M. Somers.
Acute interstitial nephritis presenting as presumed minimal change nephritic syndrome.
Pediatr Nephrol, 12 (1998), pp. 576-578
[15.]
R. Enríquez, C. González, J.B. Cabezuelo.
Relapsing steroid-responsive idiopathic acute interstitial nephritis.
Nephron, 63 (1995), pp. 462-465
[16.]
A. Spital, B.J. Panner, R.H. Sterns.
Acute idiopathic tubulointerstitial nephritis. Report of two cases and review ot the literature.
Am J Kidney Dis, 9 (1987), pp. 71-78
Copyright © 2000. Asociación Española de Pediatría
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