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Vol. 53. Núm. 4.
Páginas 369-371 (octubre 2000)
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Vol. 53. Núm. 4.
Páginas 369-371 (octubre 2000)
Acceso a texto completo
Meningitis por Haemophilus influenzae tipo f
Meningitis Due To Haemophilus Influenzae type F
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M. González Lópeza,*, A. del Pino de la Fuentea, F.J. García Martína, F. Calbo Torrecillasb, I. Obando Santaellaa, J. Camposc, A. Martínez Valverdea
a Departamento de Pediatría.
b Servicio de Medicina Preventiva. Hospital Materno Infantil de Málaga.
c Centro Nacional de Microbiología. Instituto de Salud Carlos III. Madrid
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Se describe un niño de 5 meses inmunocompetente con meningitis por Haemophilus influenzae tipo f (Hif). Había recibido previamente dos dosis de vacuna frente a Haemophilus influenzae tipo b (Hib) con polirribosilribitol fosfato conjugado con la proteína de toxoide tetánico (PRP-T). Aunque inicialmente se sospechó un fracaso vacunal a partir de los hallazgos del Gram en líquido cefalorraquídeo, se identificó posteriormente un Hif no cubierto por la vacuna conjugada.

Los serotipos no b (Hinb) deberían ser tenidos en cuenta como patógenos potenciales en niños menores de 5 años con enfermedades invasoras. Un programa de vigilancia epidemiológico sería de utilidad para monitorizar posibles incrementos futuros en la frecuencia de estos serotipos como patógenos significativos.

Palabras clave:
Haemophilus influenzae no b
Haemophilus influenzae tipo f
Enfermedad invasora
Meningitis
Key words:
Haemophilus influenzae non-b
Haemophilus influenzae type f
Invasive disease
Meningitis

We report an immunocompetent 5-month-old boy with Haemophilus influenzae type f (Hif) meningitis. The patient had previously been immunized with two doses of Hib conjugate vaccine (PRP-T). Vaccination failure was initially suspected based on Gram stain report. The results of culture identified a non-b Haemophilus influenzae capsular serotype (Hif).

Non-Hib serotypes should be considered as potential pathogenic agents in children under the age of 5 years with invasive diseases. An adequate epidemiological surveillance system would be helpful in detecting the role of these non-b Hif serotypes as significant pathogens, which appear to be on the increase.

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Copyright © 2002. Asociación Española de Pediatría
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