Notas Clínicas
Eficacia de la reducción de peso en la curación de la esteatohepatitis no alcohólica en un adolescente obeso
Effectiveness of weight loss in the treatment of non-alcoholic steatohepatitis in an obese adolescent
E. Cavanilles Walkera, A. Solar Bogaa,
, L. García Alonsoa, M.J. Lorenzo Patiñob
Autor para correspondencia
asolbog@canalejo.org
Correspondencia: Dr. A. Solar Boga. Servicio de Pediatría. Hospital Materno-Infantil. Centro Hospitalario Universitario Juan Canalejo. Jubias, 84. 15006 A Coruña. España.
Correspondencia: Dr. A. Solar Boga. Servicio de Pediatría. Hospital Materno-Infantil. Centro Hospitalario Universitario Juan Canalejo. Jubias, 84. 15006 A Coruña. España.
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"apellidos" => "Cavanilles Walker" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] ] ] 1 => array:4 [ "nombre" => "A." "apellidos" => "Solar Boga" "email" => array:1 [ 0 => "asolbog@canalejo.org" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">¿</span>" "identificador" => "cor1" ] ] ] 2 => array:3 [ "nombre" => "L." "apellidos" => "García Alonso" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] ] ] 3 => array:3 [ "nombre" => "M.J." "apellidos" => "Lorenzo Patiño" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Servicios de Pediatría, Hospital Materno-Infantil. Centro Hospitalario Universitario Juan Canalejo. A Coruña. España" "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] 1 => array:3 [ "entidad" => "Servicios de Anatomía Patológica. Hospital Materno-Infantil. Centro Hospitalario Universitario Juan Canalejo. A Coruña. España" "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor1" "etiqueta" => "⁎" "correspondencia" => "Correspondencia: Dr. A. Solar Boga. Servicio de Pediatría. Hospital Materno-Infantil. Centro Hospitalario Universitario Juan Canalejo. Jubias, 84. 15006 A Coruña. España." ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Effectiveness of weight loss in the treatment of non-alcoholic steatohepatitis in an obese adolescent" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2005-10-31" "fechaAceptado" => "2006-07-31" "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec246185" "palabras" => array:5 [ 0 => "Enfermedad hepática grasa no alcohólica" 1 => "Esteatohepatitis" 2 => "Obesidad" 3 => "Niños" 4 => "Dieta" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec246186" "palabras" => array:5 [ 0 => "Non-alcoholic fatty liver disease" 1 => "Steatohepatitis" 2 => "Obesity" 3 => "Children" 4 => "Diet" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:1 [ "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">La obesidad infantil es el trastorno nutricional más frecuente en los países desarrollados, habiendo sido declarada por la Organización Mundial de la Salud como una epidemia global. En los niños, al igual que ocurre en los adultos, la obesidad es el factor de riesgo más importante para el desarrollo de la enfermedad hepática grasa no alcohólica, por lo que es probable que se convierta en la enfermedad hepática crónica infantil más frecuente. Sin embargo las publicaciones pediátricas sobre este trastorno, que puede llegar a ocasionar una grave enfermedad hepática con riesgo para la vida, son relativamente poco numerosas, con series pequeñas y con escasos estudios histológicos. El artículo describe a un adolescente obeso en el que se demostró esteatosis grave y esteatohepatitis que respondieron con normalización analítica e histológica a la reducción de peso. Se alerta sobre el incremento de esta comorbilidad de la obesidad en la población pediátrica.</p>" ] "en" => array:1 [ "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">Childhood obesity is the most frequent nutritional disorder in developed countries and has been described as a global epidemic by the World Health Organization. In children, as in adults, obesity is the most significant risk factor for the development of non-alcoholic fatty liver disease. Therefore, it may become the most frequent chronic liver disease in children. However, pediatric publications on this disorder, which can progress to severe liver disease with risk of mortality, are scarce, with small series and few histological studies. The present article describes an obese adolescent who presented severe steatosis and steatohepatitis, which responded to weight loss with clinical and histological normalization. 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Información del artículo
ISSN: 16954033Idioma original: Español
DOI:10.1157/13098938
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