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        "resumen" => "<span class="elsevierStyleSectionTitle">Introducci&#243;n</span><p class="elsevierStyleSimplePara elsevierViewall">Los tumores del sistema nervioso central suponen el segundo conjunto de neoplasias m&#225;s frecuentes en ni&#241;os y constituyen la primera causa de muerte relacionada con el c&#225;ncer en la edad infantil&#46; No existen hallazgos cl&#237;nicos patognom&#243;nicos&#44; por lo que es preciso definir datos cl&#237;nicos que ayuden en el diagn&#243;stico&#46;</p> <span class="elsevierStyleSectionTitle">Objetivos</span><p class="elsevierStyleSimplePara elsevierViewall">Establecer los signos y s&#237;ntomas de presentaci&#243;n de los tumores cerebrales infantiles seg&#250;n la edad y su influencia en la demora diagn&#243;stica&#46;</p> <span class="elsevierStyleSectionTitle">Pacientes y m&#233;todos</span><p class="elsevierStyleSimplePara elsevierViewall">Se estudian retrospectivamente 69 pacientes con tumores de sistema nervioso central diagnosticados entre enero de 1997 y diciembre de 2002 en el Hospital Infantil Virgen del Roc&#237;o&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">El 60&#44;9&#37; de los pacientes se encontraban en los estadios cl&#237;nicos m&#225;s avanzados en el diagn&#243;stico&#46; Los signos exploratorios m&#225;s encontrados fueron el papiledema&#44; la ataxia y el estrabismo&#44; sin diferencias entre los grupos de edad&#46; Los s&#237;ntomas m&#225;s hallados en el diagn&#243;stico fueron los v&#243;mitos&#44; cefalea y alteraciones del comportamiento &#40;irritabilidad en los menores de 5 a&#241;os&#44; y la apariencia infeliz en los mayores de 5 a&#241;os&#41;&#46; La demora diagn&#243;stica fue mayor en los pacientes mayores de 5 a&#241;os&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">Los signos y s&#237;ntomas en el diagn&#243;stico de los tumores cerebrales infantiles son muy inespec&#237;ficos y es preciso tener en cuenta su posible existencia para un diagn&#243;stico lo m&#225;s precoz posible&#46;</p>"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Introduction</span><p class="elsevierStyleSimplePara elsevierViewall">Central nervous system tumors are the second most frequent group of neoplasms in children and are the main cause of cancer-related deaths in the pediatric population&#46; There are no specific clinical findings&#46; Consequently clinical data that would aid diagnosis are required&#46;</p> <span class="elsevierStyleSectionTitle">Objective</span><p class="elsevierStyleSimplePara elsevierViewall">To establish the presenting signs and symptoms of brain tumors in childhood according to age and identify their influence on diagnostic delay&#46;</p> <span class="elsevierStyleSectionTitle">Patients and methods</span><p class="elsevierStyleSimplePara elsevierViewall">We retrospectively studied 69 patients with central nervous system tumors diagnosed between January 1997 and December 2002 in the Virgen del Roc&#237;o children&#39;s hospital&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">At diagnosis&#44; 60&#46;9&#37; of the patients were in the most advanced clinical stages&#46; The most commonly found signs were papilledema&#44; ataxia and squint&#44; with no differences among age groups&#46; The most frequent symptoms were vomiting&#44; headache and behavior changes &#40;irritability in children aged less than 5 years and unhappiness in children aged more than 5 years&#41;&#46; Diagnostic delay was longer in older children&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">The diagnostic signs and symptoms of central nervous tumors are non-specific&#46; A high index of suspicion is required for early diagnosis&#46;</p>"
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Originales
Clínica de presentación de los tumores de sistema nervioso central en función de la edad
Presenting signs and symptoms of central nervous system tumors according to age
J.F. Coserria Sánchez
Autor para correspondencia
felixcos@yahoo.es

Correspondencia: Dr. J.F. Coserria Sánchez. Alte. León Herrero, 3, esc. 2, 1.° C. 11100 San Fernando. Cádiz. España.
, A.I. Garrido Ocaña, E. Quiroga Cantero, A.M.ª Reina González, A.P. Amadeu Da Costa, N. García Zarza
Servicio de Oncología Infantil. Hospital Infantil. Hospitales Universitarios Virgen del Rocío. Sevilla. España
Leído
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            "entidad" => "Servicio de Oncolog&#237;a Infantil&#46; Hospital Infantil&#46; Hospitales Universitarios Virgen del Roc&#237;o&#46; Sevilla&#46; Espa&#241;a"
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            "correspondencia" => "Correspondencia&#58; Dr&#46; J&#46;F&#46; Coserria S&#225;nchez&#46; Alte&#46; Le&#243;n Herrero&#44; 3&#44; esc&#46; 2&#44; 1&#46;&#176; C&#46; 11100 San Fernando&#46; C&#225;diz&#46; Espa&#241;a&#46;"
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      "en" => array:1 [
        "titulo" => "Presenting signs and symptoms of central nervous system tumors according to age"
      ]
    ]
    "presentadoPor" => "Presentado en&#58; XV Jornadas Internacionales sobre C&#225;ncer Infantil&#46; Sevilla&#44; marzo 2005&#46;"
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    "fechaRecibido" => "2006-05-31"
    "fechaAceptado" => "2006-09-30"
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          "palabras" => array:5 [
            0 => "Sistema nervioso central"
            1 => "Ni&#241;os"
            2 => "Cefalea"
            3 => "V&#243;mitos"
            4 => "Papiledema"
          ]
        ]
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          "clase" => "keyword"
          "titulo" => "Key words"
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          "palabras" => array:5 [
            0 => "Central nervous system"
            1 => "Children"
            2 => "Headache"
            3 => "Vomiting"
            4 => "Papilledema"
          ]
        ]
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      "es" => array:1 [
        "resumen" => "<span class="elsevierStyleSectionTitle">Introducci&#243;n</span><p class="elsevierStyleSimplePara elsevierViewall">Los tumores del sistema nervioso central suponen el segundo conjunto de neoplasias m&#225;s frecuentes en ni&#241;os y constituyen la primera causa de muerte relacionada con el c&#225;ncer en la edad infantil&#46; No existen hallazgos cl&#237;nicos patognom&#243;nicos&#44; por lo que es preciso definir datos cl&#237;nicos que ayuden en el diagn&#243;stico&#46;</p> <span class="elsevierStyleSectionTitle">Objetivos</span><p class="elsevierStyleSimplePara elsevierViewall">Establecer los signos y s&#237;ntomas de presentaci&#243;n de los tumores cerebrales infantiles seg&#250;n la edad y su influencia en la demora diagn&#243;stica&#46;</p> <span class="elsevierStyleSectionTitle">Pacientes y m&#233;todos</span><p class="elsevierStyleSimplePara elsevierViewall">Se estudian retrospectivamente 69 pacientes con tumores de sistema nervioso central diagnosticados entre enero de 1997 y diciembre de 2002 en el Hospital Infantil Virgen del Roc&#237;o&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">El 60&#44;9&#37; de los pacientes se encontraban en los estadios cl&#237;nicos m&#225;s avanzados en el diagn&#243;stico&#46; Los signos exploratorios m&#225;s encontrados fueron el papiledema&#44; la ataxia y el estrabismo&#44; sin diferencias entre los grupos de edad&#46; Los s&#237;ntomas m&#225;s hallados en el diagn&#243;stico fueron los v&#243;mitos&#44; cefalea y alteraciones del comportamiento &#40;irritabilidad en los menores de 5 a&#241;os&#44; y la apariencia infeliz en los mayores de 5 a&#241;os&#41;&#46; La demora diagn&#243;stica fue mayor en los pacientes mayores de 5 a&#241;os&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">Los signos y s&#237;ntomas en el diagn&#243;stico de los tumores cerebrales infantiles son muy inespec&#237;ficos y es preciso tener en cuenta su posible existencia para un diagn&#243;stico lo m&#225;s precoz posible&#46;</p>"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Introduction</span><p class="elsevierStyleSimplePara elsevierViewall">Central nervous system tumors are the second most frequent group of neoplasms in children and are the main cause of cancer-related deaths in the pediatric population&#46; There are no specific clinical findings&#46; Consequently clinical data that would aid diagnosis are required&#46;</p> <span class="elsevierStyleSectionTitle">Objective</span><p class="elsevierStyleSimplePara elsevierViewall">To establish the presenting signs and symptoms of brain tumors in childhood according to age and identify their influence on diagnostic delay&#46;</p> <span class="elsevierStyleSectionTitle">Patients and methods</span><p class="elsevierStyleSimplePara elsevierViewall">We retrospectively studied 69 patients with central nervous system tumors diagnosed between January 1997 and December 2002 in the Virgen del Roc&#237;o children&#39;s hospital&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">At diagnosis&#44; 60&#46;9&#37; of the patients were in the most advanced clinical stages&#46; The most commonly found signs were papilledema&#44; ataxia and squint&#44; with no differences among age groups&#46; The most frequent symptoms were vomiting&#44; headache and behavior changes &#40;irritability in children aged less than 5 years and unhappiness in children aged more than 5 years&#41;&#46; Diagnostic delay was longer in older children&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">The diagnostic signs and symptoms of central nervous tumors are non-specific&#46; A high index of suspicion is required for early diagnosis&#46;</p>"
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ISSN: 16954033
Idioma original: Español
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