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        "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">La hipomagnesemia familiar con hipercalciuria y nefrocalcinosis es un s&#237;ndrome poco frecuente que pertenece a un grupo de tubulopat&#237;as de naturaleza heterog&#233;nea&#44; cuya caracter&#237;stica com&#250;n es la p&#233;rdida urinaria de magnesio&#46;</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Se presenta el caso de un ni&#241;o de 9 a&#241;os de edad con sintomatolog&#237;a de poliuria&#44; polidipsia y enuresis&#46; Exist&#237;a nefrocalcinosis ecogr&#225;fica y radiol&#243;gica&#46; Se encontr&#243; hipomagnesemia&#44; normopotasemia&#44; hipermagnesiuria&#44; hipercalciuria&#44; acidosis tubular distal incompleta&#44; hipocitraturia e insuficiencia renal leve&#46; El tratamiento con sales de magnesio&#44; hidroclorotiacida&#44; citrato pot&#225;sico y bicarbonato s&#243;dico no ha conseguido normalizar ni la magnesiuria ni la calciuria&#46; La funci&#243;n renal y la nefrocalcinosis permanecen estables tras 3 a&#241;os de control&#46; Se trata de un nuevo caso de este raro s&#237;ndrome producido por un defecto cong&#233;nito de la resorci&#243;n tubular de magnesio&#44; y su evoluci&#243;n cl&#237;nica y anal&#237;tica tras 3 a&#241;os de seguimiento&#46;</p>"
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        "resumen" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Familiar hypomagnesemia with hypercalciuria and nephrocalcinosis is a rare syndrome belonging to the group of heterogeneous tubular diseases whose common characteristic is renal magnesium wasting&#46; We present a 9-year-old boy with polyuria&#44; polydipsia and enuresis&#46; Radiologic and ultrasonographic examinations showed nephrocalcinosis&#46; Hypomagnesemia&#44; normokaliemia&#44; hypermagnesiuria&#44; hypercalciuria&#44; incomplete distal tubular acidosis&#44; hypocitraturia and mild renal failure were found&#46; Treatment with magnesium salts&#44; hydrochlorothiazide&#44; potassium citrate and sodium bicarbonate did not restore magnesium or calcium levels to normal&#46; Renal function and nephrocalcinosis remain stable after 3-year&#39;s treatment&#46; In conclusion&#44; we report a new case of this rare syndrome caused by a congenital defect in magnesium reabsorption and discuss the evolution of the illness during 3 years&#39; treatment&#46;</p>"
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Hipomagnesemia familiar con hipercalciuria y nefrocalcinosis
Familial hypermagnesemia with hypercalciuria and nephrocalcinosis
M.J. Martín Aguado
Autor para correspondencia
a.canals@globalmed.es

Correspondencia: Dra. M.J. Martín Aguado. Servicio de Pediatría. Hospital General Universitario de Alicante. Maestro Alonso, 108. 03010 Alicante.
, A. Canals Baeza, L. Sanguino López, C. Gavilán Martín, J. Flores Serrano
Servicio de Pediatría. Hospital General Universitario de Alicante
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          "clase" => "keyword"
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            0 => "<span class="elsevierStyleItalic">Hypomagnesemia</span>"
            1 => "<span class="elsevierStyleItalic">Hypercalciuria</span>"
            2 => "<span class="elsevierStyleItalic">Nephrocalcinosis</span>"
            3 => "<span class="elsevierStyleItalic">Tubular disease</span>"
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        "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">La hipomagnesemia familiar con hipercalciuria y nefrocalcinosis es un s&#237;ndrome poco frecuente que pertenece a un grupo de tubulopat&#237;as de naturaleza heterog&#233;nea&#44; cuya caracter&#237;stica com&#250;n es la p&#233;rdida urinaria de magnesio&#46;</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Se presenta el caso de un ni&#241;o de 9 a&#241;os de edad con sintomatolog&#237;a de poliuria&#44; polidipsia y enuresis&#46; Exist&#237;a nefrocalcinosis ecogr&#225;fica y radiol&#243;gica&#46; Se encontr&#243; hipomagnesemia&#44; normopotasemia&#44; hipermagnesiuria&#44; hipercalciuria&#44; acidosis tubular distal incompleta&#44; hipocitraturia e insuficiencia renal leve&#46; El tratamiento con sales de magnesio&#44; hidroclorotiacida&#44; citrato pot&#225;sico y bicarbonato s&#243;dico no ha conseguido normalizar ni la magnesiuria ni la calciuria&#46; La funci&#243;n renal y la nefrocalcinosis permanecen estables tras 3 a&#241;os de control&#46; Se trata de un nuevo caso de este raro s&#237;ndrome producido por un defecto cong&#233;nito de la resorci&#243;n tubular de magnesio&#44; y su evoluci&#243;n cl&#237;nica y anal&#237;tica tras 3 a&#241;os de seguimiento&#46;</p>"
      ]
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        "resumen" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Familiar hypomagnesemia with hypercalciuria and nephrocalcinosis is a rare syndrome belonging to the group of heterogeneous tubular diseases whose common characteristic is renal magnesium wasting&#46; We present a 9-year-old boy with polyuria&#44; polydipsia and enuresis&#46; Radiologic and ultrasonographic examinations showed nephrocalcinosis&#46; Hypomagnesemia&#44; normokaliemia&#44; hypermagnesiuria&#44; hypercalciuria&#44; incomplete distal tubular acidosis&#44; hypocitraturia and mild renal failure were found&#46; Treatment with magnesium salts&#44; hydrochlorothiazide&#44; potassium citrate and sodium bicarbonate did not restore magnesium or calcium levels to normal&#46; Renal function and nephrocalcinosis remain stable after 3-year&#39;s treatment&#46; In conclusion&#44; we report a new case of this rare syndrome caused by a congenital defect in magnesium reabsorption and discuss the evolution of the illness during 3 years&#39; treatment&#46;</p>"
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                        0 => array:2 [
                          "etal" => false
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                          "etal" => false
                          "autores" => array:6 [
                            0 => "M&#46; Praga"
                            1 => "J&#46; Vara"
                            2 => "E&#46; Gonz&#225;lez"
                            3 => "A&#46; Andr&#233;s"
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                            2 => "V&#46; Akkari"
                            3 => "C&#46; Akatcherian"
                            4 => "P&#46; Cochat"
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                    0 => array:2 [
                      "titulo" => "Hipomagnesemia hipercalciuria y nefrocalcinosis&#58; una tubulopat&#237;a debida a un trastorno espec&#237;fico en el transporte paracelular"
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                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "D&#46;B&#46; Simon"
                            1 => "L&#46;u&#46; Yin"
                            2 => "K&#46;A&#46; Choate"
                            3 => "H&#46; Vel&#225;zquez"
                            4 => "Al-Sabban Essam"
                            5 => "M&#46; Praga"
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Información del artículo
ISSN: 16954033
Idioma original: Español
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