Consenso sobre diagnóstico y tratamiento de las alteraciones del metabolismo hidrocarbonado en la fibrosis quística
Consensus on the diagnosis and management of cystic fibrosis related diabetes
R. Barrio Castellanosa,
, A. Cos Blancob, E. García Garcíac, M. Gussinyé Cañadelld, J.F. Merino Torrese, M.T. Muñoz Calvof
Autor para correspondencia
rbarrio@hrc.insalud.es
Correspondencia: Unidad de Diabetes Pediátrica. Servicio de Pediatría. Hospital Ramón y Cajal. Crta. Colmenar Viejo km 9,4. 28034 Madrid
Correspondencia: Unidad de Diabetes Pediátrica. Servicio de Pediatría. Hospital Ramón y Cajal. Crta. Colmenar Viejo km 9,4. 28034 Madrid
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Colmenar Viejo km 9,4. 28034 Madrid" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Consensus on the diagnosis and management of cystic fibrosis related diabetes" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2000-09-30" "fechaAceptado" => "2000-09-30" "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec186527" "palabras" => array:4 [ 0 => "Fibrosis quística" 1 => "Diabetes relacionada con fibrosis quística (DRFQ)" 2 => "Diabetes mellitus" 3 => "Alteración de la tolerancia a la glucosa" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec186526" "palabras" => array:4 [ 0 => "Cystic fibrosis" 1 => "Diabetes mellitus" 2 => "Impaired glucose tolerance" 3 => "Cystic fibrosis related diabetes mellitus" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:1 [ "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">La alteración del metabolismo hidrocarbonado es una complicación frecuente de la fibrosis quística. La diabetes relacionada con fibrosis quística (DRFQ) se debe a una disminución en la secreción de la insulina secundaria a la insuficiencia pancreática. Los pacientes con fibrosis quística y diabetes presentan mayor morbilidad y mortalidad y el mismo riesgo de las complicaciones crónicas de la diabetes que los pacientes con diabetes tipo 1o 2.</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">El diagnóstico precoz y el tratamiento adecuado de la diabetes de estos pacientes es imprescindible.</p><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">En mayo de 2000 tuvo lugar en Madrid una conferencia de consenso sobre DRFQ para definir las pautas para su diagnóstico y tratamiento.</p>" ] "en" => array:1 [ "resumen" => "<p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Abnormal glucose tolerance and diabetes mellitus are a common complication of cystic fibrosis (CF). Cystic fibrosis related diabetes (CFRD) is due to decreased insulin secretion, secondary to pancreatic insufficiency. Patients with CFRD have increased morbidity and mortality and are subject to the same microvascular complications as patients with other types of diabetes. Prompt diagnosis and aggressive management of CFRD is important.</p><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">A consensus conference on CFRD was held in Madrid in May 2000 to define the current standards for the diagnosis and management of this disease in Spain.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografía" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:17 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1." 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"referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A longitudinal study of the effects of pregnancy in 325 women with CF" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "S.C. Fitz Simmons" 1 => "S. Fitzpatrick" 2 => "B. Thompson" 3 => "M. Aitkin" 4 => "S. Fiel" 5 => "G. 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| año/Mes | Html | Total | |
|---|---|---|---|
| 2024 Noviembre | 38 | 12 | 50 |
| 2024 Octubre | 315 | 59 | 374 |
| 2024 Septiembre | 231 | 38 | 269 |
| 2024 Agosto | 185 | 88 | 273 |
| 2024 Julio | 233 | 44 | 277 |
| 2024 Junio | 250 | 43 | 293 |
| 2024 Mayo | 253 | 48 | 301 |
| 2024 Abril | 288 | 47 | 335 |
| 2024 Marzo | 264 | 52 | 316 |
| 2024 Febrero | 273 | 43 | 316 |
| 2024 Enero | 273 | 54 | 327 |
| 2023 Diciembre | 217 | 35 | 252 |
| 2023 Noviembre | 309 | 47 | 356 |
| 2023 Octubre | 313 | 38 | 351 |
| 2023 Septiembre | 265 | 48 | 313 |
| 2023 Agosto | 225 | 23 | 248 |
| 2023 Julio | 221 | 43 | 264 |
| 2023 Junio | 213 | 37 | 250 |
| 2023 Mayo | 289 | 42 | 331 |
| 2023 Abril | 170 | 21 | 191 |
| 2023 Marzo | 76 | 36 | 112 |
| 2023 Febrero | 128 | 24 | 152 |
| 2023 Enero | 118 | 36 | 154 |
| 2022 Diciembre | 79 | 45 | 124 |
| 2022 Noviembre | 196 | 70 | 266 |
| 2022 Octubre | 54 | 55 | 109 |
| 2022 Septiembre | 40 | 41 | 81 |
| 2022 Agosto | 37 | 60 | 97 |
| 2022 Julio | 43 | 62 | 105 |
| 2022 Junio | 46 | 61 | 107 |
| 2022 Mayo | 38 | 52 | 90 |
| 2022 Abril | 39 | 64 | 103 |
| 2022 Marzo | 55 | 55 | 110 |
| 2022 Febrero | 33 | 41 | 74 |
| 2022 Enero | 29 | 70 | 99 |
| 2021 Diciembre | 30 | 51 | 81 |
| 2021 Noviembre | 44 | 47 | 91 |
| 2021 Octubre | 47 | 68 | 115 |
| 2021 Septiembre | 36 | 54 | 90 |
| 2021 Agosto | 32 | 55 | 87 |
| 2021 Julio | 30 | 60 | 90 |
| 2021 Junio | 38 | 58 | 96 |
| 2021 Mayo | 36 | 46 | 82 |
| 2021 Abril | 45 | 114 | 159 |
| 2021 Marzo | 51 | 38 | 89 |
| 2021 Febrero | 68 | 36 | 104 |
| 2021 Enero | 41 | 39 | 80 |
| 2020 Diciembre | 35 | 29 | 64 |
| 2020 Noviembre | 28 | 36 | 64 |
| 2020 Octubre | 24 | 25 | 49 |
| 2020 Septiembre | 31 | 11 | 42 |
| 2020 Agosto | 20 | 24 | 44 |
| 2020 Julio | 39 | 18 | 57 |
| 2020 Junio | 33 | 29 | 62 |
| 2020 Mayo | 45 | 38 | 83 |
| 2020 Abril | 49 | 27 | 76 |
| 2020 Marzo | 32 | 17 | 49 |
| 2020 Febrero | 51 | 34 | 85 |
| 2020 Enero | 45 | 20 | 65 |
| 2019 Diciembre | 47 | 35 | 82 |
| 2019 Noviembre | 33 | 18 | 51 |
| 2019 Octubre | 23 | 16 | 39 |
| 2019 Septiembre | 23 | 24 | 47 |
| 2019 Agosto | 37 | 29 | 66 |
| 2019 Julio | 36 | 26 | 62 |
| 2019 Junio | 23 | 27 | 50 |
| 2019 Mayo | 31 | 29 | 60 |
| 2019 Abril | 23 | 28 | 51 |
| 2019 Marzo | 14 | 11 | 25 |
| 2019 Febrero | 15 | 8 | 23 |
| 2019 Enero | 16 | 13 | 29 |
| 2018 Diciembre | 19 | 23 | 42 |
| 2018 Noviembre | 18 | 17 | 35 |
| 2018 Octubre | 32 | 18 | 50 |
| 2018 Septiembre | 14 | 11 | 25 |
| 2018 Julio | 1 | 0 | 1 |
| 2018 Junio | 1 | 0 | 1 |
| 2018 Mayo | 1 | 0 | 1 |
| 2018 Abril | 29 | 0 | 29 |
| 2018 Marzo | 11 | 0 | 11 |
| 2018 Febrero | 8 | 0 | 8 |
| 2018 Enero | 6 | 0 | 6 |
| 2017 Diciembre | 8 | 0 | 8 |
| 2017 Noviembre | 9 | 0 | 9 |
| 2017 Octubre | 6 | 0 | 6 |
| 2017 Septiembre | 11 | 0 | 11 |
| 2017 Agosto | 7 | 0 | 7 |
| 2017 Julio | 11 | 1 | 12 |
| 2017 Junio | 21 | 5 | 26 |
| 2017 Mayo | 17 | 19 | 36 |
| 2017 Abril | 16 | 6 | 22 |
| 2017 Marzo | 7 | 13 | 20 |
| 2017 Febrero | 5 | 7 | 12 |
| 2017 Enero | 8 | 5 | 13 |
| 2016 Diciembre | 17 | 9 | 26 |
| 2016 Noviembre | 39 | 8 | 47 |
| 2016 Octubre | 30 | 8 | 38 |
| 2016 Septiembre | 28 | 7 | 35 |
| 2016 Agosto | 23 | 6 | 29 |
| 2016 Julio | 9 | 9 | 18 |
| 2016 Junio | 0 | 8 | 8 |
| 2016 Mayo | 0 | 7 | 7 |
| 2016 Abril | 4 | 13 | 17 |
| 2016 Marzo | 1 | 0 | 1 |
| 2016 Febrero | 2 | 0 | 2 |
| 2015 Diciembre | 3 | 0 | 3 |
| 2015 Agosto | 2 | 0 | 2 |
| 2015 Julio | 10 | 0 | 10 |
| 2015 Junio | 12 | 0 | 12 |
| 2015 Mayo | 15 | 0 | 15 |
| 2015 Abril | 20 | 0 | 20 |
| 2015 Marzo | 14 | 0 | 14 |
| 2015 Febrero | 7 | 0 | 7 |
| 2015 Enero | 14 | 0 | 14 |
| 2014 Diciembre | 13 | 1 | 14 |
| 2014 Noviembre | 9 | 0 | 9 |
| 2014 Octubre | 10 | 0 | 10 |
| 2014 Septiembre | 8 | 2 | 10 |
| 2014 Agosto | 13 | 1 | 14 |
| 2014 Julio | 9 | 0 | 9 |
| 2014 Junio | 17 | 2 | 19 |
| 2014 Mayo | 31 | 0 | 31 |
| 2014 Abril | 18 | 2 | 20 |
| 2014 Marzo | 14 | 6 | 20 |
| 2014 Febrero | 10 | 6 | 16 |
| 2014 Enero | 20 | 8 | 28 |
| 2013 Diciembre | 20 | 11 | 31 |
| 2013 Noviembre | 17 | 6 | 23 |
| 2013 Octubre | 29 | 5 | 34 |
| 2013 Septiembre | 31 | 5 | 36 |
| 2013 Agosto | 15 | 6 | 21 |
| 2013 Julio | 6 | 6 | 12 |
| 2013 Junio | 3 | 6 | 9 |
| 2013 Mayo | 7 | 3 | 10 |
| 2013 Abril | 7 | 3 | 10 |
| 2013 Marzo | 8 | 2 | 10 |
| 2013 Febrero | 23 | 2 | 25 |
| 2013 Enero | 21 | 2 | 23 |
| 2012 Diciembre | 28 | 1 | 29 |
| 2012 Noviembre | 17 | 4 | 21 |
| 2012 Octubre | 4 | 1 | 5 |
| 2012 Septiembre | 0 | 1 | 1 |
| 2012 Agosto | 1 | 0 | 1 |
| 2000 Diciembre | 1819 | 0 | 1819 |
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