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Pérez Rodríguez, M. Alonso Blanco, E. Otheo de Tejada Barasoain, M.S. Maldonado Regalado, A. Muñoz Villa, R. Barrio Castellanos" "autores" => array:6 [ 0 => array:2 [ "nombre" => "M.J." "apellidos" => "Pérez Rodríguez" ] 1 => array:2 [ "nombre" => "M." "apellidos" => "Alonso Blanco" ] 2 => array:2 [ "nombre" => "E." "apellidos" => "Otheo de Tejada Barasoain" ] 3 => array:2 [ "nombre" => "M.S." "apellidos" => "Maldonado Regalado" ] 4 => array:2 [ "nombre" => "A." "apellidos" => "Muñoz Villa" ] 5 => array:2 [ "nombre" => "R." "apellidos" => "Barrio Castellanos" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1695403300774716?idApp=UINPBA00005H" "url" => "/16954033/0000005300000004/v1_201307051520/S1695403300774716/v1_201307051520/es/main.assets" ] "es" => array:15 [ "idiomaDefecto" => true "titulo" => "Valores elevados de alanina aminotransferasa y colinesterasa en niños obesos prepúberes: correlación con la concentración de insulina basal e índices antropométricos" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "330" "paginaFinal" => "334" ] ] "autores" => array:2 [ 0 => array:4 [ "autoresLista" => "R. Martos Estepa" "autores" => array:1 [ 0 => array:4 [ "nombre" => "R." "apellidos" => "Martos Estepa" "email" => array:1 [ 0 => "labpozo@mx3.redestb.es" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] ] "afiliaciones" => array:1 [ 0 => array:1 [ "entidad" => "Zona Básica de Salud Palma del Río Hospital Comarcal Valle de los Pedroches. Córdoba." ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "*" "correspondencia" => "Correspondencia: Manuel Fuentes Bocanegra, 19, 6.° 1 <span class="elsevierStyleSup">a</span> 14005 Córdoba." ] ] ] 1 => array:3 [ "autoresLista" => "F.J. Ruz Rodríguez, M. Valle Jiménez, F. Gascón Luna, F. Bermudo Guitarte, Ramón Cañete Estrada" "autores" => array:5 [ 0 => array:3 [ "nombre" => "F.J." "apellidos" => "Ruz Rodríguez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 1 => array:3 [ "nombre" => "M." "apellidos" => "Valle Jiménez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 2 => array:3 [ "nombre" => "F." "apellidos" => "Gascón Luna" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 3 => array:3 [ "nombre" => "F." "apellidos" => "Bermudo Guitarte" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 4 => array:3 [ "nombre" => "Ramón" "apellidos" => "Cañete Estrada" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff0015" ] ] ] ] "afiliaciones" => array:3 [ 0 => array:3 [ "entidad" => "Hinojosa del Duque. Córdoba. Hospital Comarcal Valle de los Pedroches. Córdoba." "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Servicio de Laboratorio Clínico. Hospital Comarcal Valle de los Pedroches. Córdoba." "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] 2 => array:3 [ "entidad" => "Unidad de Endocrinología Pediátrica. Hospital Reina Sofia. Córdoba" "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff0015" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "High levels of alanine aminotransferase and cholinesterase in obese pre-pubertal children: correlation with basal insulin concentration and anthropometric measures" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2000-01-31" "fechaAceptado" => "2000-06-30" "PalabrasClave" => array:1 [ "es" => array:2 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec186455" "palabras" => array:5 [ 0 => "Niños prepúberes" 1 => "Obesidad" 2 => "Alanina aminotransferasa" 3 => "Colinesterasa" 4 => "Grasa intraabdominal" ] ] 1 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec186456" "palabras" => array:5 [ 0 => "Pre-puberal children" 1 => "Obesity" 2 => "Alanine aminotransfera-se" 3 => "Cholinesterase" 4 => "Intraabdominal fat" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Objetivos</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Determinar si parámetros bioquímicos, utilizados en el adulto como indicadores del depósito de grasa intraabdominal (alanina aminotransferasa [ALT]), colinesterasa [ChE], gamma glutamiltransferasa [/GT], aspartato aminotransferasa [AST]), están o no elevados en obesos prepú-beres, así como valorar su posible correlación con valores basales de insulina e índices antropométricos.</p> <span class="elsevierStyleSectionTitle">Pacientes y método</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Estudio de casos y controles en niños de ambos sexos (46 obesos y 49 no obesos) de 6 a 9 años. A todos los niños se les determinó el índice de masa corporal (IMC), índice cintura/cadera e índice cintura/muslo. Se cuantificó: glucosa e insulina basal, índice insulina/glucosa, ALT, AST, gGT y ChE. La comparación de medias se realizó por la t de Student. La correlación entre variables se evaluó por el coeficiente de correlación de Pearson.</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Los grupos fueron homogéneos, no presentaron diferencias significativas en la edad ni en el sexo. La concentración de glucosa fue similar en ambos grupos, en tanto que la de insulina, ALT, ChE, gGT e índice ALT/AST fueron significativamente superiores en el grupo de obesos. La concentración de ALT y de ChE se correlacionaron positivamente con la insulina, el índice insulina/glucosa, así como con el IMC e índice cintura/cadera.</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Parámetros bioquímicos como la ALT y la ChE pueden ser de utilidad en el niño obeso como medida indirecta del depósito de grasa. El aumento de estos parámetros depende, a esta edad, tanto de la concentración de insulina como del grado de obesidad y distribución de la grasa.</p>" ] "en" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">To determine whether biochemical parameters, used in adult to indicate intraabdominal fat deposits [alanine aminotransferase (ALT), cholinesterase (ChE), gamma-glutamyltransferase (?-GT), and aspartate aminotransferase (AST)] are increased in obese pre-pubertal children and to evaluate their possible correlation with basal insulin levels and anthropometric measures.</p> <span class="elsevierStyleSectionTitle">Patients and method</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Study of obese pediatric patients and controls of both sexes (46 obese and 49 not obese) aged between 6 and 9 years. Body mass index (BMI), waist/hip and waist/thigh ratio were determined in all children. Glucose and basal insulin concentrations, the insulin/glucose index, ALT, AST, #yGT and ChE were quantified in all children. Student's t-test was used to perform the mean comparison and Pearson's correlation coefficient was used to evaluate the correlation between variables.</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">The groups were homogeneous, presenting no significant differences in age or sex. Glucose concentrations were similar in both groups, while those of insulin, ALT, ChE, #yGT and the ALT/AST index were significantly higher in the group of obese children. Concentrations of ALT and ChE were positively correlated with insulin and the insulin/glucose index, BMI, and waist/hip ratio.</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Biochemical parameters such as ALT and ChE may be useful as indirect measure of fat deposits in obese children. In this age group, an increase in these parameters depends on insulin concentration as well as on the degree of obesity and fat distribution.</p>" ] ] "NotaPie" => array:1 [ 0 => array:1 [ "nota" => "<p class="elsevierStyleNotepara">Este trabajo recoge datos preliminares del proyecto "Estudio metabólico en niños obesos. 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año/Mes | Html | Total | |
---|---|---|---|
2024 Noviembre | 9 | 16 | 25 |
2024 Octubre | 76 | 47 | 123 |
2024 Septiembre | 47 | 65 | 112 |
2024 Agosto | 72 | 95 | 167 |
2024 Julio | 45 | 50 | 95 |
2024 Junio | 45 | 34 | 79 |
2024 Mayo | 64 | 54 | 118 |
2024 Abril | 49 | 25 | 74 |
2024 Marzo | 39 | 49 | 88 |
2024 Febrero | 48 | 45 | 93 |
2024 Enero | 49 | 33 | 82 |
2023 Diciembre | 35 | 21 | 56 |
2023 Noviembre | 48 | 23 | 71 |
2023 Octubre | 50 | 33 | 83 |
2023 Septiembre | 45 | 35 | 80 |
2023 Agosto | 38 | 23 | 61 |
2023 Julio | 34 | 29 | 63 |
2023 Junio | 51 | 35 | 86 |
2023 Mayo | 68 | 33 | 101 |
2023 Abril | 46 | 20 | 66 |
2023 Marzo | 39 | 35 | 74 |
2023 Febrero | 45 | 22 | 67 |
2023 Enero | 48 | 29 | 77 |
2022 Diciembre | 80 | 30 | 110 |
2022 Noviembre | 67 | 43 | 110 |
2022 Octubre | 82 | 52 | 134 |
2022 Septiembre | 91 | 51 | 142 |
2022 Agosto | 52 | 62 | 114 |
2022 Julio | 52 | 51 | 103 |
2022 Junio | 48 | 47 | 95 |
2022 Mayo | 52 | 47 | 99 |
2022 Abril | 58 | 54 | 112 |
2022 Marzo | 55 | 57 | 112 |
2022 Febrero | 78 | 51 | 129 |
2022 Enero | 74 | 57 | 131 |
2021 Diciembre | 60 | 52 | 112 |
2021 Noviembre | 47 | 51 | 98 |
2021 Octubre | 60 | 74 | 134 |
2021 Septiembre | 45 | 46 | 91 |
2021 Agosto | 53 | 31 | 84 |
2021 Julio | 55 | 50 | 105 |
2021 Junio | 66 | 51 | 117 |
2021 Mayo | 85 | 32 | 117 |
2021 Abril | 201 | 74 | 275 |
2021 Marzo | 129 | 15 | 144 |
2021 Febrero | 108 | 17 | 125 |
2021 Enero | 108 | 24 | 132 |
2020 Diciembre | 77 | 24 | 101 |
2020 Noviembre | 83 | 12 | 95 |
2020 Octubre | 75 | 15 | 90 |
2020 Septiembre | 64 | 12 | 76 |
2020 Agosto | 69 | 17 | 86 |
2020 Julio | 89 | 21 | 110 |
2020 Junio | 69 | 19 | 88 |
2020 Mayo | 64 | 21 | 85 |
2020 Abril | 39 | 16 | 55 |
2020 Marzo | 50 | 11 | 61 |
2020 Febrero | 38 | 13 | 51 |
2020 Enero | 54 | 19 | 73 |
2019 Diciembre | 63 | 40 | 103 |
2019 Noviembre | 63 | 36 | 99 |
2019 Octubre | 51 | 13 | 64 |
2019 Septiembre | 60 | 33 | 93 |
2019 Agosto | 54 | 25 | 79 |
2019 Julio | 84 | 43 | 127 |
2019 Junio | 75 | 55 | 130 |
2019 Mayo | 152 | 50 | 202 |
2019 Abril | 178 | 47 | 225 |
2019 Marzo | 63 | 23 | 86 |
2019 Febrero | 65 | 23 | 88 |
2019 Enero | 65 | 16 | 81 |
2018 Diciembre | 55 | 16 | 71 |
2018 Noviembre | 52 | 31 | 83 |
2018 Octubre | 66 | 14 | 80 |
2018 Septiembre | 40 | 10 | 50 |
2018 Julio | 1 | 0 | 1 |
2018 Junio | 1 | 0 | 1 |
2018 Mayo | 6 | 0 | 6 |
2018 Abril | 15 | 0 | 15 |
2018 Marzo | 19 | 0 | 19 |
2018 Febrero | 11 | 0 | 11 |
2018 Enero | 8 | 0 | 8 |
2017 Diciembre | 14 | 0 | 14 |
2017 Noviembre | 26 | 0 | 26 |
2017 Octubre | 19 | 0 | 19 |
2017 Septiembre | 11 | 0 | 11 |
2017 Agosto | 5 | 0 | 5 |
2017 Julio | 24 | 2 | 26 |
2017 Junio | 25 | 39 | 64 |
2017 Mayo | 30 | 24 | 54 |
2017 Abril | 26 | 43 | 69 |
2017 Marzo | 26 | 32 | 58 |
2017 Febrero | 26 | 22 | 48 |
2017 Enero | 22 | 15 | 37 |
2016 Diciembre | 23 | 15 | 38 |
2016 Noviembre | 48 | 19 | 67 |
2016 Octubre | 40 | 26 | 66 |
2016 Septiembre | 40 | 28 | 68 |
2016 Agosto | 34 | 16 | 50 |
2016 Julio | 22 | 14 | 36 |
2016 Junio | 1 | 0 | 1 |
2016 Abril | 1 | 0 | 1 |
2016 Marzo | 5 | 0 | 5 |
2016 Febrero | 0 | 12 | 12 |
2015 Diciembre | 2 | 0 | 2 |
2015 Octubre | 0 | 18 | 18 |
2015 Agosto | 2 | 17 | 19 |
2015 Julio | 5 | 0 | 5 |
2015 Junio | 9 | 17 | 26 |
2015 Mayo | 12 | 0 | 12 |
2015 Abril | 14 | 16 | 30 |
2015 Marzo | 10 | 0 | 10 |
2015 Febrero | 16 | 8 | 24 |
2015 Enero | 26 | 3 | 29 |
2014 Diciembre | 13 | 2 | 15 |
2014 Noviembre | 13 | 1 | 14 |
2014 Octubre | 10 | 1 | 11 |
2014 Septiembre | 10 | 3 | 13 |
2014 Agosto | 15 | 3 | 18 |
2014 Julio | 17 | 3 | 20 |
2014 Junio | 25 | 3 | 28 |
2014 Mayo | 25 | 3 | 28 |
2014 Abril | 15 | 8 | 23 |
2014 Marzo | 20 | 9 | 29 |
2014 Febrero | 6 | 8 | 14 |
2014 Enero | 17 | 8 | 25 |
2013 Diciembre | 17 | 9 | 26 |
2013 Noviembre | 16 | 6 | 22 |
2013 Octubre | 24 | 8 | 32 |
2013 Septiembre | 20 | 12 | 32 |
2013 Agosto | 14 | 14 | 28 |
2013 Julio | 6 | 5 | 11 |
2013 Junio | 4 | 4 | 8 |
2013 Mayo | 4 | 2 | 6 |
2013 Abril | 5 | 6 | 11 |
2013 Marzo | 5 | 6 | 11 |
2013 Febrero | 15 | 3 | 18 |
2013 Enero | 31 | 1 | 32 |
2012 Diciembre | 25 | 1 | 26 |
2012 Noviembre | 26 | 5 | 31 |
2012 Octubre | 0 | 1 | 1 |
2012 Septiembre | 0 | 1 | 1 |
2012 Agosto | 1 | 0 | 1 |
2000 Septiembre | 5976 | 0 | 5976 |