Crisis parciales en recién nacido con esclerosis tuberosa
Partial Seizures In A Newbornwith Tuberous Sclerosis
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"apellidos" => "Olivas Domínguez" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1695403300773103?idApp=UINPBA00005H" "url" => "/16954033/0000005200000002/v1_201307051448/S1695403300773103/v1_201307051448/es/main.assets" ] "es" => array:14 [ "idiomaDefecto" => true "titulo" => "Crisis parciales en recién nacido con esclerosis tuberosa" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "164" "paginaFinal" => "167" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "M.P. Falero Gallego, A. Verdú Pérez, Y. López Lozano, A. Ureta Huertos" "autores" => array:4 [ 0 => array:3 [ "nombre" => "M.P." "apellidos" => "Falero Gallego" "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "A." "apellidos" => "Verdú Pérez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 2 => array:3 [ "nombre" => "Y." "apellidos" => "López Lozano" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 3 => array:3 [ "nombre" => "A." "apellidos" => "Ureta Huertos" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Sección de Neonatología. Servicio de Pediatría. Hospital Virgen de la Salud. Toledo." "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Unidad de Neuropediatría. Servicio de Pediatría. Hospital Virgen de la Salud. Toledo." "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "*" "correspondencia" => "Correspondencia: Dra. M.<span class="elsevierStyleSup">a</span>Piedad Falero Gallego. C/ Cerrillo, 36. 45810 Villanueva del Alcardete. Toledo." ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Partial Seizures In A Newbornwith Tuberous Sclerosis" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "1999-04-30" "fechaAceptado" => "1999-08-31" "PalabrasClave" => array:1 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec186232" "palabras" => array:4 [ 0 => "Esclerosis tuberosa" 1 => "Recién nacido" 2 => "Rabdomioma cardíaco" 3 => "Imagen por resonancia magnética" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">La esclerosis tuberosa es un síndrome neurocutáneocaracterizado por el crecimiento de hamartomas en distintosórganos. Son hallazgos típicos: manchas cutáneashipocrómicas, angiofibromas faciales, nódulos subependimarios,tubérculos corticales, rabdomiomas cardíacos,hamartomas retinianos, etc. Son frecuentes la epilepsia yel retraso psicomotor. La herencia es autosómica dominante,aunque muchos de los casos son esporádicos. Raravez debutan en el período neonatal.Se describe un recién nacido a término, mujer, sin antecedentesde interés, que ingresa al tercer día de vida porpresentar crisis convulsivas clónicas de miembros izquierdos.A la exploración física presenta una arritmiacardíaca con extrasístoles, siendo el resto normal. Laecocardiografía demostró la presencia de rabdomiomas.La resonancia magnética cerebral evidenció túberes corticalesy nódulos subependimarios. En el examen de fondode ojo se encontró un hamartoma retiniano derecho.Al mes de vida eran ya evidentes máculas cutáneas acrómicas.En su evolución, la niña presentó espasmos infantilesy, posteriormente, crisis parciales complejas de difícilcontrol farmacológico asociadas a un grave retrasopsicomotor. El estudio de los padres fue normal.Queremos destacar la infrecuencia del diagnóstico deesclerosis tuberosa durante el período neonatal, así comoel carácter excepcional del debut en nuestra paciente comocrisis convulsivas en el período neonatal precoz, pocasveces referido en la literatura.</p>" ] "en" => array:1 [ "resumen" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Tuberous sclerosis is characterized by the potential forhamartomatous growth in multiple organs. Common manifestationsare hypomelanotic spots, facial angiofibromas,subependymal hamartomas, cortical tubers, cardiacrhabdomyomas, retinal hamartomas, and so on. Seizuresand mental retardation are frequent. It is an autosomaldominant disease but there is a high percentage of spontaneousmutations. Neonatal diagnosis is exceptional.We report a case of a female term newborn who presentedpartial motor seizures at the third day of life. Physicalexamination revealed only a disturbance of cardiacrhythm. Echocardiography showed ventricular intramuralrhabdomyomas. Magnetic resonance imaging disclosedperiventricular subependymal nodules and corticaltubers. A retinal hamartoma was found in the right eye.At the age of 1 month, hypomelanotic spots were evidenton the back skin. The patient had infantile spasms, followedby poorly controlled partial complex seizures togetherwith severe psychomotor retardation. Examinationof both parents was normal.We discuss the uncommon diagnosis of tuberous sclerosisduring the neonatal period, as well as the exceptionalmode of presentation of our patient, with seizures inthe early neonatal period, a phenomenon rarely reportedin the literature.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografía" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:20 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Prenatal MRI diagnosis of fetal cerebral tuberous sclerosis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "P. Sonigo" 1 => "A. Elmaleh" 2 => "L. Fermont" 3 => "A.L. Delezoíde" 4 => "V. Mirlesse" 5 => "F. 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| año/Mes | Html | Total | |
|---|---|---|---|
| 2024 Noviembre | 6 | 13 | 19 |
| 2024 Octubre | 26 | 52 | 78 |
| 2024 Septiembre | 42 | 36 | 78 |
| 2024 Agosto | 58 | 95 | 153 |
| 2024 Julio | 37 | 50 | 87 |
| 2024 Junio | 47 | 41 | 88 |
| 2024 Mayo | 39 | 39 | 78 |
| 2024 Abril | 44 | 44 | 88 |
| 2024 Marzo | 44 | 42 | 86 |
| 2024 Febrero | 36 | 42 | 78 |
| 2024 Enero | 24 | 30 | 54 |
| 2023 Diciembre | 31 | 33 | 64 |
| 2023 Noviembre | 23 | 33 | 56 |
| 2023 Octubre | 35 | 23 | 58 |
| 2023 Septiembre | 25 | 28 | 53 |
| 2023 Agosto | 23 | 27 | 50 |
| 2023 Julio | 32 | 42 | 74 |
| 2023 Junio | 26 | 33 | 59 |
| 2023 Mayo | 36 | 26 | 62 |
| 2023 Abril | 24 | 35 | 59 |
| 2023 Marzo | 22 | 33 | 55 |
| 2023 Febrero | 22 | 25 | 47 |
| 2023 Enero | 15 | 27 | 42 |
| 2022 Diciembre | 27 | 37 | 64 |
| 2022 Noviembre | 53 | 60 | 113 |
| 2022 Octubre | 46 | 50 | 96 |
| 2022 Septiembre | 74 | 41 | 115 |
| 2022 Agosto | 77 | 65 | 142 |
| 2022 Julio | 50 | 58 | 108 |
| 2022 Junio | 32 | 43 | 75 |
| 2022 Mayo | 30 | 39 | 69 |
| 2022 Abril | 18 | 54 | 72 |
| 2022 Marzo | 31 | 59 | 90 |
| 2022 Febrero | 34 | 35 | 69 |
| 2022 Enero | 26 | 42 | 68 |
| 2021 Diciembre | 30 | 66 | 96 |
| 2021 Noviembre | 41 | 69 | 110 |
| 2021 Octubre | 48 | 66 | 114 |
| 2021 Septiembre | 30 | 77 | 107 |
| 2021 Agosto | 29 | 68 | 97 |
| 2021 Julio | 25 | 46 | 71 |
| 2021 Junio | 31 | 62 | 93 |
| 2021 Mayo | 47 | 35 | 82 |
| 2021 Abril | 54 | 105 | 159 |
| 2021 Marzo | 67 | 53 | 120 |
| 2021 Febrero | 67 | 29 | 96 |
| 2021 Enero | 48 | 17 | 65 |
| 2020 Diciembre | 45 | 16 | 61 |
| 2020 Noviembre | 31 | 25 | 56 |
| 2020 Octubre | 28 | 17 | 45 |
| 2020 Septiembre | 38 | 6 | 44 |
| 2020 Agosto | 28 | 8 | 36 |
| 2020 Julio | 20 | 20 | 40 |
| 2020 Junio | 29 | 11 | 40 |
| 2020 Mayo | 33 | 19 | 52 |
| 2020 Abril | 24 | 21 | 45 |
| 2020 Marzo | 36 | 13 | 49 |
| 2020 Febrero | 35 | 25 | 60 |
| 2020 Enero | 37 | 18 | 55 |
| 2019 Diciembre | 50 | 33 | 83 |
| 2019 Noviembre | 19 | 17 | 36 |
| 2019 Octubre | 13 | 18 | 31 |
| 2019 Septiembre | 39 | 24 | 63 |
| 2019 Agosto | 28 | 25 | 53 |
| 2019 Julio | 26 | 40 | 66 |
| 2019 Junio | 42 | 23 | 65 |
| 2019 Mayo | 63 | 34 | 97 |
| 2019 Abril | 41 | 28 | 69 |
| 2019 Marzo | 23 | 17 | 40 |
| 2019 Febrero | 25 | 11 | 36 |
| 2019 Enero | 28 | 17 | 45 |
| 2018 Diciembre | 20 | 16 | 36 |
| 2018 Noviembre | 19 | 18 | 37 |
| 2018 Octubre | 37 | 19 | 56 |
| 2018 Septiembre | 13 | 4 | 17 |
| 2018 Agosto | 1 | 0 | 1 |
| 2018 Julio | 1 | 0 | 1 |
| 2018 Mayo | 2 | 0 | 2 |
| 2018 Abril | 7 | 1 | 8 |
| 2018 Marzo | 6 | 0 | 6 |
| 2018 Febrero | 5 | 0 | 5 |
| 2018 Enero | 5 | 0 | 5 |
| 2017 Diciembre | 7 | 0 | 7 |
| 2017 Noviembre | 7 | 0 | 7 |
| 2017 Octubre | 9 | 0 | 9 |
| 2017 Septiembre | 9 | 0 | 9 |
| 2017 Agosto | 5 | 0 | 5 |
| 2017 Julio | 10 | 0 | 10 |
| 2017 Junio | 20 | 14 | 34 |
| 2017 Mayo | 15 | 6 | 21 |
| 2017 Abril | 13 | 9 | 22 |
| 2017 Marzo | 12 | 37 | 49 |
| 2017 Febrero | 6 | 0 | 6 |
| 2017 Enero | 12 | 5 | 17 |
| 2016 Diciembre | 30 | 8 | 38 |
| 2016 Noviembre | 46 | 8 | 54 |
| 2016 Octubre | 67 | 11 | 78 |
| 2016 Septiembre | 57 | 24 | 81 |
| 2016 Agosto | 51 | 27 | 78 |
| 2016 Julio | 33 | 25 | 58 |
| 2016 Junio | 1 | 0 | 1 |
| 2016 Mayo | 2 | 0 | 2 |
| 2016 Abril | 2 | 0 | 2 |
| 2016 Marzo | 5 | 0 | 5 |
| 2016 Febrero | 3 | 0 | 3 |
| 2015 Diciembre | 3 | 0 | 3 |
| 2015 Noviembre | 1 | 0 | 1 |
| 2015 Octubre | 2 | 0 | 2 |
| 2015 Agosto | 1 | 0 | 1 |
| 2015 Julio | 14 | 0 | 14 |
| 2015 Junio | 5 | 0 | 5 |
| 2015 Mayo | 19 | 0 | 19 |
| 2015 Abril | 10 | 0 | 10 |
| 2015 Marzo | 5 | 0 | 5 |
| 2015 Febrero | 10 | 0 | 10 |
| 2015 Enero | 11 | 0 | 11 |
| 2014 Diciembre | 15 | 0 | 15 |
| 2014 Noviembre | 10 | 0 | 10 |
| 2014 Octubre | 10 | 0 | 10 |
| 2014 Septiembre | 7 | 0 | 7 |
| 2014 Agosto | 8 | 0 | 8 |
| 2014 Julio | 6 | 0 | 6 |
| 2014 Junio | 19 | 0 | 19 |
| 2014 Mayo | 21 | 0 | 21 |
| 2014 Abril | 16 | 0 | 16 |
| 2014 Marzo | 11 | 0 | 11 |
| 2014 Febrero | 11 | 0 | 11 |
| 2014 Enero | 15 | 0 | 15 |
| 2013 Diciembre | 14 | 0 | 14 |
| 2013 Noviembre | 12 | 0 | 12 |
| 2013 Octubre | 24 | 0 | 24 |
| 2013 Septiembre | 15 | 0 | 15 |
| 2013 Agosto | 11 | 0 | 11 |
| 2013 Julio | 3 | 0 | 3 |
| 2013 Junio | 2 | 0 | 2 |
| 2013 Mayo | 3 | 0 | 3 |
| 2013 Abril | 1 | 0 | 1 |
| 2013 Marzo | 2 | 0 | 2 |
| 2013 Febrero | 11 | 0 | 11 |
| 2013 Enero | 4 | 0 | 4 |
| 2012 Diciembre | 2 | 0 | 2 |
| 2012 Noviembre | 2 | 0 | 2 |
| 2012 Octubre | 1 | 0 | 1 |
| 2012 Septiembre | 3 | 0 | 3 |
| 2012 Julio | 1 | 0 | 1 |
| 2000 Febrero | 2769 | 0 | 2769 |
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