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                        "paginaFinal" => "719"
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                          0 => array:2 [
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                        "paginaInicial" => "644"
                        "paginaFinal" => "650"
                        "link" => array:1 [
                          0 => array:2 [
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                            3 => "D&#46;K&#46; Wesson"
                            4 => "R&#46;M&#46; Filler"
                            5 => "B&#46; Shandling"
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                      ]
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                      "Revista" => array:6 [
                        "tituloSerie" => "J Pediatr Surg"
                        "fecha" => "1992"
                        "volumen" => "27"
                        "paginaInicial" => "1315"
                        "paginaFinal" => "1317"
                        "link" => array:1 [
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                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1328584"
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                        "paginaFinal" => "310"
                        "link" => array:1 [
                          0 => array:2 [
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                        "paginaFinal" => "609"
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                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/4366135"
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                            0 => "S&#46;S&#46; Fajans"
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                        "tituloSerie" => "Endocrinol Metab Clin North Am"
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                        "paginaFinal" => "74"
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Dificultad diagnóstica del insulinoma en una paciente con epilepsia mioclónica juvenil
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F. Vílchez López
Autor para correspondencia
fjvil@hotmail.com

Correspondencia: Francisco Vílchez López. Servicio de Pediatría. Hospital Ramón y Cajal. Crta. de Colmenar Viejo, km 9,101. 28034 Madrid.
, R. Barrio Castellanos, A. Belanguer Quintana, J. Pérez de Oteiza, M. Martínez Pardo
Servicio de Pediatría. Hospital Ramón y Cajal. Madrid. España
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Bibliografía
[1.]
F.J. Service, M.M. McMahon, P.C. O’Brien, D.J. Ballard.
Functioning insulinoma-incidence, recurrence and long term survival of patients: A 60 year study.
Mayo Clin Proc, 66 (1991), pp. 711-719
[2.]
V. Glaser, H. Hirch, H. Landau.
Persistent hyperinsulinemic hypoglycaemia of infancy: Long term octeotride treatment without pancreatectomy.
J Pediatr, 123 (1993), pp. 644-650
[3.]
I.M. Modlin, L.H. Tang.
Approaches to the diagnosis of gut neuroendocrine tumors: The last word (today).
Gastroenterology, 112 (1997), pp. 583-590
[4.]
B.T. Jaksic, M. Yaman, P. Thorner, D.K. Wesson, R.M. Filler, B. Shandling.
A 20-year review of pediatric pancreatic tumors.
J Pediatr Surg, 27 (1992), pp. 1315-1317
[5.]
A.M. Dizon, S. Kowalyk, B.J. Hoogwerf.
Neuroglycopenic and other symptoms in patients with insulinomas.
Am J Med, 106 (1999), pp. 307-310
[6.]
P. Stefanini, M. Carboni, N. Patrasi, Basoli.
Beta islet cell tumors of the pancreas: Results of a study on 1,067 cases.
Surgery, 75 (1974), pp. 597-609
[7.]
S.S. Fajans, A.I. Vinik.
Insulin producer islet cell tumors.
Endocrinol Metab Clin North Am, 18 (1980), pp. 45-74
[8.]
E.A. Mittendorf, Y.C. Liu, C.R. McHenry.
Giant insulinoma: Case report and review of the literature.
J Clin Endocrinol Metabolism, 90 (2005), pp. 575-580
[9.]
J.P. Dolan, J.A. Norton.
Occult insulinoma.
[10.]
M.C.C. Machado, J.E. Monteiro da Cunha, J. Jukemura, T. Bacchella, S. Penteado, E.E. Abdo, et al.
Insulinoma: Diagnostic strategies and surgical treatment. A 22 year experience.
Hepatogastroenterology, 48 (2001), pp. 854-858
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