Resultados de una estrategia terapéutica frente a la enuresis nocturna monosintomática

Rodríguez do Forno, A.; Ariceta Iraola, G.

doi:10.1016/S1695-4033(01)78647-X

Anales de Pediatría (English Edition)

ISSN: 2341-2879

The Spanish Pediatric Association (Asociación Española de Pediatría, AEP) has as one of its main objectives the dissemination of rigorous and up-to-date scientific information on the various areas of pediatrics. Annals of Pediatrics is an open access journal that serves as the Association's Scientific Expression Organ and constitutes the vehicle through which members communicate. Annals of Pediatrics publishes, in English and Spanish, original research papers on pediatrics, as well as review articles prepared by experts in each specialty, and guidelines or positioning documents prepared by the different Societies/Specialized Sections integrated into the Spanish Pediatric Association. The journal, a reference for Spanish-speaking pediatrics, is indexed in the most important international databases: Index Medicus/Medline IBECS, IME, SCOPUS, Science Citation Index Expanded, Journal Citations Report, Embase/Excerpta Medica, Directory of Open Access Journals (DOAJ).

Indexed in:

Index Medicus/Medline IBECS, IME, SCOPUS, Science Citation Index Expanded, Journal Citations Report, Embase/Excerpta Medica, Directory of Open Access Journals (DOAJ)

Se estudiaron 84 pacientes enuréticos de 6 a 14 años de edad. Los niños de 6 a 7 años recibieron tratamiento con desmopresina, asociando en los no respondedores oxibutinina y posteriormente si continuaban mojando alarma. Los mayores de 7 años recibieron aleatoriamente tratamiento con alarma o con alarma más desmopresina; a los no respondedores se les trató con desmopresina.

Resultados

En los niños de 6-7 años el porcentaje acumulado de respuesta fue del 72 %. Los menos mojadores fueron los que respondieron a desmopresina. En los niños con edad superior a 7 años, la respuesta con alarma fue del 73,3% y del 58,6% en los tratados con alarma y desmopresina; la respuesta acumulada, tras la aplicación de desmopresina a los no respondedores, pasó a ser del 80 y 62 %, respectivamente.

Conclusión

En el grupo de 6-7 años la desmopresina está indicada como terapia inicial. La asociación con oxibutinina aumentó la eficacia del tratamiento, sobre todo en los niños más mojadores. En los mayores de 7 años es la alarma la terapia más efectiva y con menor número de recaídas, sin observarse una mejor respuesta al asociar desmopresina y alarma según nuestro protocolo.

Palabras clave:

nuresis nocturna monosintomática

Desmopresina

Oxibutinina

Alarma

Background

There are many therapeutic options against enuresis.

Objective

To evaluate several therapies introduced progressively to treat monosymptomatic nocturnal enuresis.

Methods

Eighty-four patients, aged 6 to 14 years old, were studied. The 6-7 year olds were treated with desmopressin and oxybutynin was added in non-responders. If enuresis persisted, Alarm was given. Children over 7 years of age were randomly divided and treated with Alarm or Alarm plus desmopressin. Non-responders were treated with desmopressin alone.

Results

In children aged 6-7 years the cumulative response was 72 %. Those who wetted themselves less responded to desmopressin. In children over 7 years of age, response to Alarm was 73.3% and response to Alarm plus desmopressin was 58.6 %. In non-responders the cumulative response after desmopressin treatment increased to 80 % and 62 % respectively.

Key words:

onosymptomatic nocturnal enuresis

Desmopressin

Oxybutynin

Alarm

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