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Vol. 52. Issue 5.
Pages 443-446 (1 May 2000)
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Vol. 52. Issue 5.
Pages 443-446 (1 May 2000)
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Perfil lipídico en niños de Rivas-Vaciamadrid. Seguimiento de 2 años
Lipid profile in rivas-vaciamadrid children. Two years follow-up
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M.J. Peláez Gómez de Salazara, M. Sánchez Bayleb,*, A. González-Requejob, C. Ruiz-Jarabo Quemadab, J. Asensio Antónb, J. Otero de Becerreab
a Centro de Salud de Rivas-Vaciamadrid.
b Grupo de Trabajo sobre Factores de Riesgo Cardiovascular. Hospital del Niño Jesús. Madrid.
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Objetivos

Evaluar el perfil lipídico en niños después de 2 años de seguimiento.

Métodos

Se trata de un estudio de cohorte longitudinal. Seguimiento a los 2 años de un grupo de niños estudiados inicialmente a los 6 años de edad. A todos se les determinó en analítica sanguínea el colesterol total, triglicéridos, cLDL, cHDL, apoproteínas A y B, y los índices CT/cHDL, cLDL/cHDL, Apo B/A e índice aterogénico.

Resultados

Se ha encontrado una buena correlación entre los valores iniciales y finales estudiados del perfil lipídico (r greater than 0,5; p less than 0,001) para todos los parámetros estudiados salvo los triglicéridos, Apo A y cociente Apo B/A. El riesgo relativo de tener colesterol total > 200 mg/dl, cLDL > 135 mg/dl y Apo B > 100 mg/dl en el seguimiento fue de 9,51, 5,18 y 8 para quienes tenían en el estudio inicial estos mismos valores. Los valores del perfil lipídico y de los índices estudiados fueron mejores en el control a los 2 años, pero sólo tuvieron significación estadística en los varones.

Conclusiones

En los niños que tenían en el estudio inicial 6 años de edad, a los 2 años de seguimiento existe una buena relación entre los valores del perfil lipídico y los índices evaluados.

Palabras clave:
Colesterol
Perfil lipídico
Seguimiento
Niños
Objective

Evaluate the lipid profiles in children after two years of follow-up.

Methods

Longitudinal cohort study. A two years follow-up of a group of children since they were 6 years old. Blood analysis were carried in every children measuring total cholesterol, triglycerides, cLDL, cHDL, apoproteins Aand B.It also included TD/cHDL, cLDL/cHDL, Apo B/A ratios and atherogenic index.

Results

A significant correlation has been found between initial and final values of all the parameters studied of lipid profile (r 0.5; p 0.001) except for triglycerides, Apo A and Apo B/A ratio. The relative risk of having total cholesterol > 200 mg/dl, cLDL > 135 mg/dl and Apo B > 100 mg/dl in the follow-up was of 9.51, 5.18 and 8 for those children who had in the initial study these same values. The values of lipid profile and of the index studied improved in the two years of follow-up. This improvement has an statistical signification only in men.

Conclusions

There is a significant correlation between the values of the lipid profile and the index measured in those children who were six years old in the beginning of the two years follow-up.

Cholesterol:
Lipid profile
Follow-up
Children
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Copyright © 2000. Asociación Española de Pediatría
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