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Images in Paediatrics
Lymphoproliferative disorder under the appearance of mask-related folliculitis
Trastorno linfoproliferativo bajo apariencia de foliculitis por mascarilla
Álvaro Vázquez-Péreza,
Corresponding author
, David López-Delgadob, Francisco Fernández-Segoviac, Jesús Tercedor-Sánchezb, Juan Luis Santos-Péreza
a Servicio de Pediatría, Hospital Universitario Materno Infantil Virgen de las Nieves, Granada, Spain
b Servicio de Dermatología, Hospital Universitario Virgen de las Nieves, Granada, Spain
c Servicio de Anatomía Patológica, Hospital Universitario Clínico San Cecilio, Granada, Spain
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    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">A patient aged 8 years sought care for a lesion in the right cheek with onset 4 months prior and no history of insect bite&#46; The followup by the paediatrician was carried out by telephone on account of the restrictions to in-person care placed during the COVID-19 pandemic&#46; Initially&#44; the suspected diagnosis was folliculitis associated with mask use&#44; for which the neologism <span class="elsevierStyleItalic">maskne</span> has been coined&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">Successive treatment with topical antibiotics &#40;clindamycin and mupirocin&#41; and an oral antibiotic &#40;cefadroxil&#41; achieved no improvement&#44; and the lesion continued to grow&#46; The patient presented with a plaque measuring about 3&#8239;&#215;&#8239;3&#8239;cm in the malar region&#44; elastic and eroded on the surface &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>&#41;&#46; A polymerase chain reaction test for detection of <span class="elsevierStyleItalic">Leishmania</span> on skin scrapings was negative&#46; Examination of a biopsy specimen led to histological diagnosis of cutaneous CD4&#43; small&#47;medium T-cell lymphoproliferative disorder &#40;CSMLPD&#41; &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>&#41;&#46; The patient received topical treatment with clobetasol propionate&#44; with improvement of the lesion at 1 month of treatment &#40;<a class="elsevierStyleCrossRef" href="#fig0015">Fig&#46; 3</a>&#41;&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><elsevierMultimedia ident="fig0015"></elsevierMultimedia><p id="par0015" class="elsevierStylePara elsevierViewall">Cutaneous CD4&#43; small&#47;medium T-cell lymphoproliferative disorder is a primary cutaneous lymphoma provisionally classified as a proliferative disorder to emphasize its benign course and discourage aggressive systemic treatment&#46;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> The differential diagnosis includes other cutaneous T and B cell lymphomas&#44; reactive lymphoproliferative disorders&#44; pseudolymphoma and lupus erythematosus tumidus&#46;<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> Treatment options include surgery&#44; topical or intralesional steroids and phototherapy&#46;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a></p><p id="par0020" class="elsevierStylePara elsevierViewall">The prolonged use of masks during the COVID-19 pandemic has been associated with the development and worsening of facial dermatoses&#46;<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a> Their increased prevalence and the widespread use of the term <span class="elsevierStyleItalic">maskne</span> may obscure and result in underdiagnosis of other&#44; more complex<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a> or infrequent disorders&#46; An appropriate differential diagnosis must be carried out&#44; as not everything is <span class="elsevierStyleItalic">maskne</span>&#46;</p></span>"
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