Scientific Letter
Usefulness of chest ultrasound in a neonatal infection due to SARS-CoV-2
Utilidad de la ecografía torácica en infección neonatal por SARS-CoV-2
Read
3645
Timeswas read the article
1499
Total PDF
2146
Total HTML
Share statistics
array:25 [ "pii" => "S234128792100048X" "issn" => "23412879" "doi" => "10.1016/j.anpede.2021.04.001" "estado" => "S300" "fechaPublicacion" => "2021-06-01" "aid" => "2891" "copyright" => "Asociación Española de Pediatría" "copyrightAnyo" => "2021" "documento" => "simple-article" "crossmark" => 1 "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/" "subdocumento" => "crp" "cita" => "An Pediatr (Barc). 2021;94:412-3" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "Traduccion" => array:1 [ "es" => array:20 [ "pii" => "S1695403320302174" "issn" => "16954033" "doi" => "10.1016/j.anpedi.2020.04.027" "estado" => "S300" "fechaPublicacion" => "2021-06-01" "aid" => "2891" "copyright" => "Asociación Española de Pediatría" "documento" => "simple-article" "crossmark" => 1 "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/" "subdocumento" => "crp" "cita" => "An Pediatr (Barc). 2021;94:412-3" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "es" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Carta científica</span>" "titulo" => "Utilidad de la ecografía torácica en infección neonatal por SARS-CoV-2" "tienePdf" => "es" "tieneTextoCompleto" => "es" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "412" "paginaFinal" => "413" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Usefulness of chest ultrasound in a neonatal infection due to SARS-CoV-2" ] ] "contieneTextoCompleto" => array:1 [ "es" => true ] "contienePdf" => array:1 [ "es" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figura 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1271 "Ancho" => 1508 "Tamanyo" => 150263 ] ] "descripcion" => array:1 [ "es" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Convergencia de líneas B (flecha) y engrosamiento pleural (flecha discontinua).</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Ana Pineda Caplliure, Manuel Porcar Almela, Andrea Navarro Albert, Elvira Muñoz Vicente, Beatriz Mansilla Roig" "autores" => array:5 [ 0 => array:2 [ "nombre" => "Ana" "apellidos" => "Pineda Caplliure" ] 1 => array:2 [ "nombre" => "Manuel" "apellidos" => "Porcar Almela" ] 2 => array:2 [ "nombre" => "Andrea" "apellidos" => "Navarro Albert" ] 3 => array:2 [ "nombre" => "Elvira" "apellidos" => "Muñoz Vicente" ] 4 => array:2 [ "nombre" => "Beatriz" "apellidos" => "Mansilla Roig" ] ] ] ] ] "idiomaDefecto" => "es" "Traduccion" => array:1 [ "en" => array:9 [ "pii" => "S234128792100048X" "doi" => "10.1016/j.anpede.2021.04.001" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S234128792100048X?idApp=UINPBA00005H" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1695403320302174?idApp=UINPBA00005H" "url" => "/16954033/0000009400000006/v1_202106020556/S1695403320302174/v1_202106020556/es/main.assets" ] ] "itemSiguiente" => array:20 [ "pii" => "S2341287921000533" "issn" => "23412879" "doi" => "10.1016/j.anpede.2020.05.009" "estado" => "S300" "fechaPublicacion" => "2021-06-01" "aid" => "2890" "copyright" => "Asociación Española de Pediatría" "documento" => "simple-article" "crossmark" => 1 "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/" "subdocumento" => "crp" "cita" => "An Pediatr (Barc). 2021;94:413-5" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "en" => array:10 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Scientific Letter</span>" "titulo" => "Description and assessment of medical student rotation in Primary Care Paediatrics" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "413" "paginaFinal" => "415" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Descripción y evaluación de la rotación de estudiantes de Medicina por Pediatría de Atención Primaria" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:5 [ 0 => array:2 [ "autoresLista" => "Maria Aparicio Rodrigo" "autores" => array:1 [ 0 => array:2 [ "nombre" => "Maria" "apellidos" => "Aparicio Rodrigo" ] ] ] 1 => array:2 [ "autoresLista" => "Carmen Martínez González" "autores" => array:1 [ 0 => array:2 [ "nombre" => "Carmen" "apellidos" => "Martínez González" ] ] ] 2 => array:2 [ "autoresLista" => "María Garcia-Onieva Artazcoz" "autores" => array:1 [ 0 => array:2 [ "nombre" => "María" "apellidos" => "Garcia-Onieva Artazcoz" ] ] ] 3 => array:2 [ "autoresLista" => "Ángeles Hernáez Cobeño" "autores" => array:1 [ 0 => array:2 [ "nombre" => "Ángeles" "apellidos" => "Hernáez Cobeño" ] ] ] 4 => array:2 [ "autoresLista" => "Jesús López-Herce Cid" "autores" => array:1 [ 0 => array:2 [ "nombre" => "Jesús" "apellidos" => "López-Herce Cid" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S1695403320302162" "doi" => "10.1016/j.anpedi.2020.05.020" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1695403320302162?idApp=UINPBA00005H" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2341287921000533?idApp=UINPBA00005H" "url" => "/23412879/0000009400000006/v1_202106030800/S2341287921000533/v1_202106030800/en/main.assets" ] "itemAnterior" => array:20 [ "pii" => "S2341287920302544" "issn" => "23412879" "doi" => "10.1016/j.anpede.2020.12.002" "estado" => "S300" "fechaPublicacion" => "2021-06-01" "aid" => "2993" "copyright" => "Asociación Española de Pediatría" "documento" => "article" "crossmark" => 1 "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/" "subdocumento" => "fla" "cita" => "An Pediatr (Barc). 2021;94:403-11" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "en" => array:13 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Original Article</span>" "titulo" => "Tuberculosis in the paediatric age group: a reflection on transmission" "tienePdf" => "en" "tieneTextoCompleto" => "en" "tieneResumen" => array:2 [ 0 => "en" 1 => "es" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "403" "paginaFinal" => "411" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Tuberculosis en la edad pediátrica: una reflexión sobre la transmisión" ] ] "contieneResumen" => array:2 [ "en" => true "es" => true ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:8 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1070 "Ancho" => 2214 "Tamanyo" => 124356 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0005" "detalle" => "Fig. " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Number of new cases of TB reported in children aged 0 to 14 years: comparison of national data and sample data.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Joana Brandão Silva, Joana Caldeira Santos, Luciana Barbosa, Isabel Carvalho" "autores" => array:4 [ 0 => array:2 [ "nombre" => "Joana Brandão" "apellidos" => "Silva" ] 1 => array:2 [ "nombre" => "Joana Caldeira" "apellidos" => "Santos" ] 2 => array:2 [ "nombre" => "Luciana" "apellidos" => "Barbosa" ] 3 => array:2 [ "nombre" => "Isabel" "apellidos" => "Carvalho" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S1695403320304380" "doi" => "10.1016/j.anpedi.2020.04.035" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1695403320304380?idApp=UINPBA00005H" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2341287920302544?idApp=UINPBA00005H" "url" => "/23412879/0000009400000006/v1_202106030800/S2341287920302544/v1_202106030800/en/main.assets" ] "en" => array:15 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Scientific Letter</span>" "titulo" => "Usefulness of chest ultrasound in a neonatal infection due to SARS-CoV-2" "tieneTextoCompleto" => true "saludo" => "Dear Editor:" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "412" "paginaFinal" => "413" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Ana Pineda Caplliure, Manuel Porcar Almela, Andrea Navarro Albert, Elvira Muñoz Vicente, Beatriz Mansilla Roig" "autores" => array:5 [ 0 => array:3 [ "nombre" => "Ana" "apellidos" => "Pineda Caplliure" "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 1 => array:4 [ "nombre" => "Manuel" "apellidos" => "Porcar Almela" "email" => array:1 [ 0 => "dr.porcaralmela@gmail.com" ] "referencia" => array:3 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] 2 => array:2 [ "etiqueta" => "*" "identificador" => "cor0005" ] ] ] 2 => array:3 [ "nombre" => "Andrea" "apellidos" => "Navarro Albert" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 3 => array:3 [ "nombre" => "Elvira" "apellidos" => "Muñoz Vicente" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 4 => array:3 [ "nombre" => "Beatriz" "apellidos" => "Mansilla Roig" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Servicio de Pediatría, Hospital Universitario Doctor Peset, Valencia, Spain" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Departamento de Pediatría, Obstetricia y Ginecología, Universidad de Valencia, Valencia, Spain" "etiqueta" => "b" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Utilidad de la ecografía torácica en infección neonatal por SARS-CoV-2" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1271 "Ancho" => 1508 "Tamanyo" => 150263 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Converging B-lines (solid arrow) and pleural thickening (dotted arrow).</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">In December 2019, an outbreak of a novel coronavirus (severe acute respiratory syndrome coronavirus 2 [SARS-CoV-2]) was reported, having originated in Wuhan, Hubei province, China.</p><p id="par0010" class="elsevierStylePara elsevierViewall">Most studies on the subject performed to date have focused on adult patients, and the current evidence on the pediatric population is scarce, especially when it comes to newborns.<a class="elsevierStyleCrossRefs" href="#bib0035"><span class="elsevierStyleSup">1,2</span></a> In Spain, one of the epicenters of the pandemic, as many as 146,690 cases have been reported.</p><p id="par0015" class="elsevierStylePara elsevierViewall">We present a case of horizontal transmission of infection by SARS-CoV-2 in a male neonate aged 10 days confirmed by a positive real-time reverse transcriptase polymerase chain reaction (RT-PCR) test for SARS-CoV-2, describing the clinical presentation, diagnosis, treatment and outcome of the patient.</p><p id="par0020" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleItalic">Clinical case:</span> male neonate aged 10 days brought to the primary care center with fever, with a rectal temperature of 38.5<span class="elsevierStyleHsp" style=""></span>°C and no other symptoms, with good tolerance of formula feeding. The neonate was referred to the emergency department and admitted to hospital to evaluate the fever without a source. The mother, aged 26 years, had received prenatal care, with normal antenatal ultrasounds and a spontaneous vaginal delivery at 39<span class="elsevierStyleSup">2+</span> weeks of gestation, in the absence of perinatal risk factors for infection (negative for β-haemolytic streptococcus and a total duration of ruptured of membranes of 4<span class="elsevierStyleHsp" style=""></span>h), a birth weight of 3220<span class="elsevierStyleHsp" style=""></span>g and Apgar scores of 10/10.</p><p id="par0025" class="elsevierStylePara elsevierViewall">The relevant history consisted of a household environment with the father, mother and paternal grandfather experiencing cold symptoms, cough and nasal discharge in the absence of fever.</p><p id="par0030" class="elsevierStylePara elsevierViewall">The evaluation included blood tests, blood culture, urinalysis, lumbar puncture, collection of nasopharyngeal aspirate to test for the presence of adenovirus, influenza A and B, respiratory syncytial virus and SARS-CoV-2 with the RT-PCR test. Empiric antibiotherapy was initiated while awaiting the results of culture and viral testing.</p><p id="par0035" class="elsevierStylePara elsevierViewall">The results of the tests performed at admission were as follows: complete blood count with normal red blood cell indices, a white blood cell count of 7.4<span class="elsevierStyleHsp" style=""></span>×<span class="elsevierStyleHsp" style=""></span>10<span class="elsevierStyleSup">9</span>/L with 40.5% lymphocytes and 21.6% monocytes; procalcitonin, 0.20<span class="elsevierStyleHsp" style=""></span>ng/mL; C-reactive protein <5<span class="elsevierStyleHsp" style=""></span>mg/L; normal findings of examination of cerebrospinal fluid and normal findings of urinalysis. The RT-PCR test was positive for SARS-CoV-2 and negative for all other viruses. Given this result, both parents underwent the RT-PCR test for SARS-CoV-2, which turned out positive.</p><p id="par0040" class="elsevierStylePara elsevierViewall">At admission, the infant presented with a temperature of 36.9<span class="elsevierStyleHsp" style=""></span>°C, a heart rate (HR) of 144<span class="elsevierStyleHsp" style=""></span>bpm, a respiratory rate (RR) of 42<span class="elsevierStyleHsp" style=""></span>bpm and an oxygen saturation of 100% in room air, well-appearing, with good peripheral perfusion and good bilateral inspiration without no abnormal breath sounds.</p><p id="par0045" class="elsevierStylePara elsevierViewall">At 24<span class="elsevierStyleHsp" style=""></span>h from admission, the RR increased to 60<span class="elsevierStyleHsp" style=""></span>bpm and the HR in the 160–180<span class="elsevierStyleHsp" style=""></span>bpm range, which prompted performance of a chest X-ray and echocardiography, both with normal findings, and a chest ultrasound that revealed pleural thickening, converging B-lines in the posterior chest and subpleural consolidation at the lung base level of the right hemithorax (<a class="elsevierStyleCrossRefs" href="#fig0005">Figs. 1 and 2</a>). Subsequently, the patient developed apnoea, and capillary blood gas analysis detected mild carbon dioxide retention (pH, 7.38; pCO<span class="elsevierStyleInf">2</span>, 48.4, bicarbonate, 26.4; lactate, 1.2), leading to initiation of treatment with caffeine and administration of supplemental oxygen in the incubator with a peak FiO<span class="elsevierStyleInf">2</span> of 0.3. On day 3 from admission, antibiotherapy was discontinued on account of the negative culture results, and the patient showed clinical improvement with a gradual decrease in oxygen requirements and resolution of apnoea, and he was discharged at 9 days from admission. Serological tests conducted at admission were IgM<span class="elsevierStyleSup">−</span> and IgG<span class="elsevierStyleSup">−</span>, with evidence of seroconversion at day 16 from onset (IgM<span class="elsevierStyleSup">−</span>, IgG<span class="elsevierStyleSup">+</span>).</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0050" class="elsevierStylePara elsevierViewall">The case presented here was a case of horizontal transmission, as the patient lived with other 8 individuals in the household, of who 3 reported cold symptoms, which led to testing of household members despite the absence of fever.</p><p id="par0055" class="elsevierStylePara elsevierViewall">We ought to highlight the importance of the chest ultrasound, an aspect that has not been described in previously published pediatric cases, as it detects abnormalities at an earlier stage compared to the X-ray. In our patient, it revealed abnormalities before the development of apnoeic episodes and need for supplemental oxygen, abnormalities that were undetectable in the plain radiograph, and it is the method currently used in the triage of adult patients with suspected coronavirus disease 2019 (COVID-19).<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">3</span></a> We did not find evidence of the gastrointestinal symptoms described in other cases.<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">4</span></a></p><p id="par0060" class="elsevierStylePara elsevierViewall">Further research is required to establish the lung ultrasound features found in patients with COVID-19 and the course of the disease in the neonatal population, and any household members with mild cold symptoms should be tested to prevent transmission in this age group. In the context of the current pandemic, it is important to include the RT-PCR test for detection of SARS-CoV-2 infection in the assessment of the febrile neonate, as indicated by current protocols,<a class="elsevierStyleCrossRef" href="#bib0055"><span class="elsevierStyleSup">5</span></a> taking into account the role of the viral load in this age group as it is done in adults.<a class="elsevierStyleCrossRef" href="#bib0060"><span class="elsevierStyleSup">6</span></a></p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "⋆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Pineda Caplliure A, Porcar Almela M, Navarro Albert A, Muñoz Vicente E, Mansilla Roig B. Utilidad de la ecografía torácica en infección neonatal por SARS-CoV-2. An Pediatr (Barc). 2021;94:412–413.</p>" ] ] "multimedia" => array:2 [ 0 => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1271 "Ancho" => 1508 "Tamanyo" => 150263 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Converging B-lines (solid arrow) and pleural thickening (dotted arrow).</p>" ] ] 1 => array:7 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 993 "Ancho" => 1508 "Tamanyo" => 105678 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Subpleural consolidation at the level of the posterior basal region of the right lung (arrow).</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0015" "bibliografiaReferencia" => array:6 [ 0 => array:3 [ "identificador" => "bib0035" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Clinical characteristics of novel coronavirus disease 2019 (COVID-19) in newborns, infants and children" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "H. Hong" 1 => "Y. Wang" 2 => "H.T. Chung" 3 => "C.J. Chen" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.pedneo.2020.03.001" "Revista" => array:6 [ "tituloSerie" => "Pediatr Neonatol" "fecha" => "2020" "volumen" => "61" "paginaInicial" => "131" "paginaFinal" => "132" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/32199864" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0040" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Primer caso de infección neonatal por SARS-CoV-2 en España" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "C. Alonso" 1 => "M. López" 2 => "M.T. Moral" 3 => "B. Flores" 4 => "C. Pallás" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.anpedi.2020.03.002" "Revista" => array:2 [ "tituloSerie" => "An Pediatr (Barc)" "fecha" => "2020" ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0045" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Point-of-Care Lung Ultrasound findings in novel coronavirus disease-19 pnemoniae: a case report and potential applications during COVID-19 outbreak" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "D. Buonsenso" 1 => "A. Piano" 2 => "F. Raffaelli" 3 => "N. Bonadia" 4 => "K. de Gaetano Donati" 5 => "F. Franceschi" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.26355/eurrev_202003_20549" "Revista" => array:6 [ "tituloSerie" => "Eur Rev Med Pharmacol Sci" "fecha" => "2020" "volumen" => "24" "paginaInicial" => "2776" "paginaFinal" => "2780" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/32196627" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0050" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "SARS-CoV-2 infection with gastrointestinal symptoms as the first manifestation in a neonate [Article in Chinese]" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "J. Wang" 1 => "D. Wang" 2 => "G.C. Chen" 3 => "X.W. Tao" 4 => "L.K. Zeng" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Zhongguo Dang Dai Er Ke Za Zhi" "fecha" => "2020" "volumen" => "22" "paginaInicial" => "211" "paginaFinal" => "214" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/32204755" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0055" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:1 [ "referenciaCompleta" => "Recomendaciones para el manejo del recién nacido en relación con la infección por SARS-CoV-2. Sociedad española de neonatología. Available from: <a target="_blank" href="https://www.seneo.es/images/site/noticias/home/Recomendaciones_SENeo_SARS-CoV-2Version_50.pdf">https://www.seneo.es/images/site/noticias/home/Recomendaciones_SENeo_SARS-CoV-2Version_50.pdf</a> [cited 6 April 2020]." ] ] ] 5 => array:3 [ "identificador" => "bib0060" "etiqueta" => "6" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Coronavirus disease (COVID-19) and neonate: what neonatologist need to know" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "Q. Lu" 1 => "Y. Shi" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1002/jmv.25740" "Revista" => array:6 [ "tituloSerie" => "J Med Virol" "fecha" => "2020" "volumen" => "92" "paginaInicial" => "564" "paginaFinal" => "567" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/32115733" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/23412879/0000009400000006/v1_202106030800/S234128792100048X/v1_202106030800/en/main.assets" "Apartado" => array:4 [ "identificador" => "38181" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Scientific letters" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/23412879/0000009400000006/v1_202106030800/S234128792100048X/v1_202106030800/en/main.pdf?idApp=UINPBA00005H&text.app=https://analesdepediatria.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S234128792100048X?idApp=UINPBA00005H" ]
| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 4 | 6 | 10 |
| 2024 October | 47 | 33 | 80 |
| 2024 September | 65 | 37 | 102 |
| 2024 August | 88 | 57 | 145 |
| 2024 July | 57 | 28 | 85 |
| 2024 June | 59 | 32 | 91 |
| 2024 May | 71 | 38 | 109 |
| 2024 April | 45 | 32 | 77 |
| 2024 March | 46 | 20 | 66 |
| 2024 February | 48 | 29 | 77 |
| 2024 January | 42 | 28 | 70 |
| 2023 December | 43 | 21 | 64 |
| 2023 November | 52 | 41 | 93 |
| 2023 October | 44 | 24 | 68 |
| 2023 September | 45 | 25 | 70 |
| 2023 August | 34 | 16 | 50 |
| 2023 July | 54 | 28 | 82 |
| 2023 June | 49 | 28 | 77 |
| 2023 May | 58 | 26 | 84 |
| 2023 April | 34 | 17 | 51 |
| 2023 March | 56 | 26 | 82 |
| 2023 February | 34 | 17 | 51 |
| 2023 January | 35 | 21 | 56 |
| 2022 December | 57 | 22 | 79 |
| 2022 November | 64 | 33 | 97 |
| 2022 October | 64 | 42 | 106 |
| 2022 September | 41 | 34 | 75 |
| 2022 August | 55 | 46 | 101 |
| 2022 July | 51 | 49 | 100 |
| 2022 June | 43 | 33 | 76 |
| 2022 May | 58 | 33 | 91 |
| 2022 April | 51 | 45 | 96 |
| 2022 March | 53 | 41 | 94 |
| 2022 February | 52 | 42 | 94 |
| 2022 January | 61 | 33 | 94 |
| 2021 December | 48 | 54 | 102 |
| 2021 November | 50 | 37 | 87 |
| 2021 October | 57 | 82 | 139 |
| 2021 September | 30 | 39 | 69 |
| 2021 August | 21 | 38 | 59 |
| 2021 July | 34 | 36 | 70 |
| 2021 June | 77 | 62 | 139 |
| 2021 May | 60 | 59 | 119 |
| 2021 April | 9 | 9 | 18 |
Show all
