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class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "José Miguel" "apellidos" => "Lera Imbuluzqueta" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 2 => array:3 [ "nombre" => "Miriam" "apellidos" => "Alkorta Gurrutxaga" "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Servicio de Microbiología, Hospital Universitario de Donostia, Donostia, Guipúzcoa, Spain" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Servicio de Dermatología, Hospital Universitario de Donostia, Donostia, Guipúzcoa, Spain" "etiqueta" => "b" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "<span class="elsevierStyleItalic">Arthroderma benhamiae</span> en pacientes con cobayas" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1200 "Ancho" => 800 "Tamanyo" => 151456 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Kerion celsi.</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleItalic">Arthroderma benhamiae</span> is the teleomorph of a zoonotic dermatophytic fungus that belongs to the <span class="elsevierStyleItalic">Trichophyton mentagrophytes</span> species complex.<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">1</span></a> Small rodents are its main reservoir, especially guinea pigs, in which it can cause an inflammatory cutaneous infection. It has also been isolated from larger animals, such as dogs and cats. In recent years, the incidence of infection by this fungus has increased due to the increase in the number of guinea pigs and other small rodents that are household pets.<a class="elsevierStyleCrossRefs" href="#bib0030"><span class="elsevierStyleSup">2,3</span></a> This dermatophyte can cause tinea corporis, tinea faciei and in some cases kerion celsi. Onychomycosis has been reported in very rare cases.<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">2</span></a> It is characterised by highly inflammatory lesions, especially in children, who frequently develop kerion celsi. Besides children, it is frequently isolated from adolescents and immunosuppressed individuals. In the early stage of infection, the skin lesions may be confused with impetigo, which delays diagnosis. We now proceed to present 2 cases diagnosed in our microbiology laboratory in the span of 3 months.</p><p id="par0010" class="elsevierStylePara elsevierViewall">Girl aged 3 years that presented with an inflammatory and suppurative lesion with onset 2 months prior that was diagnosed as kerion celsi. At onset, the patient developed lesions in the mouth and nose that were treated with topical antibiotics due to suspected impetigo. Subsequently, the patient developed additional erythematous plaques with a honey-coloured crust in the parieto-occipital region, which were treated with topical mupirocin and oral amoxicillin-clavulanic acid.</p><p id="par0015" class="elsevierStylePara elsevierViewall">Due to the unfavourable response to treatment, she was referred to the dermatology department, where she received a diagnosis of tinea capitis and started topical treatment with a terbinafine cream and a sertaconazole nitrate gel. The relevant findings of the history were a past episode of tinea corporis in the father and the presence of a pet guinea pig in the household that also had skin lesions. Two weeks later, the lesions had progressed into abscesses (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>). The abscesses were actively drained every 48<span class="elsevierStyleHsp" style=""></span>h, with collection of a sample of the exudate and dystrophic hairs for submission to the microbiology laboratory. The patient received a prescription for a new course of treatment with oral itraconazole (62.5<span class="elsevierStyleHsp" style=""></span>mg/day) and a miconazole/hydrocortisone cream for 3 weeks.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0020" class="elsevierStylePara elsevierViewall">Girl aged 8 years referred to the dermatology department for assessment of a bald plaque in the scalp more than 1 month after onset of symptoms (lesions initially developed in the left breast and spread to the scalp over time). During the history taking, she reported that her pet guinea pigs had developed bald patches before she contracted the disease. A sample was collected for culture and the patient received treatment with terbinafine at a dose of 125<span class="elsevierStyleHsp" style=""></span>mg/day for 1 month combined with topical administration of a terbinafine cream in the morning and a mometasone furoate and acetylsalicylic acid cream at night.</p><p id="par0025" class="elsevierStylePara elsevierViewall">The microbiology laboratory processed the samples of both patients (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>). In both cases, 15 days after submission the laboratory report indicated the presence of a fungus initially identified as a <span class="elsevierStyleItalic">Trichophyton</span> species. The definitive identification as <span class="elsevierStyleItalic">Arthroderma benhamiae</span> was achieved by the analysis of the sequence of the internal transcribed spacer (ITS) region of ribosomal RNA.</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0030" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleItalic">Arthroderma benhamiae</span> usually causes mild infections that respond to topical treatment with ciclopirox, imidazole or terbinafine. However, cases with more extensive involvement and tinea capitis require treatment with oral antifungals. In patients with kerion celsi, early diagnosis and prompt initiation of treatment are of the essence due to the risk of scarring hair loss. There are few studies on the use of different antifungals to treat infections by this fungus. Most authors report use of terbinafine, griseofulvin, itraconazole or fluconazole for a minimum of 4–6 weeks,<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">4</span></a> with favourable outcomes. Epidemiological data, such as the presence of pets, especially guinea pigs, are important clues for suspecting and correctly diagnosing this fungal skin infection.</p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Martín-Peñaranda T, Lera Imbuluzqueta JM, Alkorta Gurrutxaga M. <span class="elsevierStyleItalic">Arthroderma benhamiae</span> en pacientes con cobayas. An Pediatr (Barc). 2019;90:51–52.</p>" ] ] "multimedia" => array:2 [ 0 => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1200 "Ancho" => 800 "Tamanyo" => 151456 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Kerion celsi.</p>" ] ] 1 => array:7 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 718 "Ancho" => 800 "Tamanyo" => 57965 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Appearance of <span class="elsevierStyleItalic">Arthroderma benhamiae</span> growth in Sabouraud agar plate.</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0015" "bibliografiaReferencia" => array:4 [ 0 => array:3 [ "identificador" => "bib0025" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:3 [ "comentario" => "Available in: <a class="elsevierStyleInterRef" target="_blank" id="intr0010" href="https://doi.org/10.4067/S0716-10182015000400009">https://doi.org/10.4067/S0716-10182015000400009</a>" "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Complejo <span class="elsevierStyleItalic">Trichophyton mentagrophytes</span>" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "L. 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2024 July | 75 | 41 | 116 |
2024 June | 62 | 21 | 83 |
2024 May | 76 | 41 | 117 |
2024 April | 65 | 35 | 100 |
2024 March | 59 | 29 | 88 |
2024 February | 39 | 36 | 75 |
2024 January | 66 | 21 | 87 |
2023 December | 87 | 27 | 114 |
2023 November | 65 | 30 | 95 |
2023 October | 73 | 27 | 100 |
2023 September | 80 | 32 | 112 |
2023 August | 70 | 20 | 90 |
2023 July | 60 | 35 | 95 |
2023 June | 70 | 19 | 89 |
2023 May | 86 | 26 | 112 |
2023 April | 47 | 13 | 60 |
2023 March | 76 | 27 | 103 |
2023 February | 66 | 16 | 82 |
2023 January | 57 | 14 | 71 |
2022 December | 61 | 37 | 98 |
2022 November | 72 | 33 | 105 |
2022 October | 104 | 39 | 143 |
2022 September | 79 | 22 | 101 |
2022 August | 68 | 46 | 114 |
2022 July | 70 | 29 | 99 |
2022 June | 70 | 28 | 98 |
2022 May | 77 | 32 | 109 |
2022 April | 77 | 25 | 102 |
2022 March | 105 | 62 | 167 |
2022 February | 117 | 36 | 153 |
2022 January | 110 | 35 | 145 |
2021 December | 89 | 44 | 133 |
2021 November | 87 | 46 | 133 |
2021 October | 148 | 78 | 226 |
2021 September | 266 | 69 | 335 |
2021 August | 81 | 47 | 128 |
2021 July | 76 | 37 | 113 |
2021 June | 71 | 46 | 117 |
2021 May | 78 | 53 | 131 |
2021 April | 153 | 103 | 256 |
2021 March | 124 | 42 | 166 |
2021 February | 80 | 25 | 105 |
2021 January | 88 | 24 | 112 |
2020 December | 78 | 22 | 100 |
2020 November | 61 | 23 | 84 |
2020 October | 75 | 17 | 92 |
2020 September | 70 | 14 | 84 |
2020 August | 68 | 17 | 85 |
2020 July | 83 | 23 | 106 |
2020 June | 69 | 8 | 77 |
2020 May | 57 | 17 | 74 |
2020 April | 56 | 21 | 77 |
2020 March | 49 | 8 | 57 |
2020 February | 46 | 12 | 58 |
2020 January | 49 | 15 | 64 |
2019 December | 70 | 19 | 89 |
2019 November | 46 | 10 | 56 |
2019 October | 59 | 11 | 70 |
2019 September | 101 | 10 | 111 |
2019 August | 53 | 22 | 75 |
2019 July | 68 | 16 | 84 |
2019 June | 93 | 33 | 126 |
2019 May | 115 | 50 | 165 |
2019 April | 108 | 31 | 139 |
2019 March | 49 | 21 | 70 |
2019 February | 109 | 21 | 130 |
2019 January | 156 | 13 | 169 |
2018 December | 11 | 11 | 22 |
2018 November | 8 | 5 | 13 |