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"paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "102" "paginaFinal" => "104" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Nerea Bilbao, Paula Santiago, Beatriz Azkunaga, Santiago Mintegi" "autores" => array:5 [ 0 => array:2 [ "nombre" => "Nerea" "apellidos" => "Bilbao" ] 1 => array:2 [ "nombre" => "Paula" "apellidos" => "Santiago" ] 2 => array:2 [ "nombre" => "Beatriz" "apellidos" => "Azkunaga" ] 3 => array:4 [ "nombre" => "Santiago" "apellidos" => "Mintegi" "email" => array:1 [ 0 => "santiago.mintegi@osakidetza.eus" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 4 => array:1 [ "colaborador" => "el Grupo de Trabajo de Intoxicaciones de la Sociedad Española de Urgencias de Pediatría" ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Servicio de Urgencias de Pediatría, Hospital Universitario Cruces, Universidad del País Vasco, Bilbao, Vizcaya, Spain" "identificador" => "aff0005" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Intoxicaciones agudas no intencionadas asociadas a recipientes no originales" ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Inappropriate habits in the storage of potentially toxic substances, such as the use of non-original containers, may facilitate unintentional acute poisonings in the paediatric age group<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">1</span></a> and have been associated with a potentially greater severity,<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">2</span></a> although few studies provide evidence on this subject.</p><p id="par0010" class="elsevierStylePara elsevierViewall">The main aim of our study was to analyse whether unintentional acute paediatric poisonings by substances stored in non-original containers are more severe than the rest of poisonings. Our secondary objective was to learn the characteristics of these poisonings.</p><p id="par0015" class="elsevierStylePara elsevierViewall">We conducted a descriptive study based on a prospective register of the cases of poisoning documented in the 59 paediatric emergency departments (PEDs) that participate in the Observatorio Toxicológico (Toxicology Surveillance System) of the Sociedad Española de Urgencias de Pediatría (Spanish Society of Paediatric Emergency Medicine) between October 2008 and September 2014. We determined severity based on diagnostic tests, the treatment received, admission to hospital or the paediatric intensive care unit, sequelae and fatalities.</p><p id="par0020" class="elsevierStylePara elsevierViewall">The study was approved by the Committee of Ethics and Clinical Research of the Basque Country.</p><p id="par0025" class="elsevierStylePara elsevierViewall">The participating hospitals are listed in <a class="elsevierStyleCrossRef" href="#sec0005">Appendix 1</a>.</p><p id="par0030" class="elsevierStylePara elsevierViewall">During the period under study, the 59 PEDs received 339<span class="elsevierStyleHsp" style=""></span>086 visits, of which 902 corresponded to poisonings. Out of all poisoning cases, 639 were unintended, and the type of container in which the substance was stored was documented in 611 (95.6%). In 100 of these cases (16.3%), the toxic substance had not been stored in its original container, a circumstance that was more common in cases of poisoning with household products (57/200 [28.5%]; 95% CI, 22.2%–34.7%) than in cases of poisoning with medications (31/341 [9.0%]; 95% CI, 5.9%–12.0%). <a class="elsevierStyleCrossRef" href="#tbl0005">Table 1</a> compares the characteristics of the 200 unintentional acute poisonings with household products based on the type of container used for storage.</p><elsevierMultimedia ident="tbl0005"></elsevierMultimedia><p id="par0035" class="elsevierStylePara elsevierViewall">When it came to poisoning with medications, those that involved substances stored in non-original containers corresponded more frequently to combined drug intoxications (6/31 [19.3%] compared to 13/310 [4.2%] of unintentional poisonings with medications stored in their original containers; <span class="elsevierStyleItalic">P</span><span class="elsevierStyleHsp" style=""></span><<span class="elsevierStyleHsp" style=""></span>.005), and involved psychotropic drugs more frequently (12/31 [38.7%] compared to 56/310 [18.0%]; <span class="elsevierStyleItalic">P</span><span class="elsevierStyleHsp" style=""></span><<span class="elsevierStyleHsp" style=""></span>.05), with no differences between age groups or in severity. When we analysed the data for cases in which the setting of the poisoning was documented, we found that these poisonings occurred most frequently in the parents’ bedroom (8/31 [25.8%] vs 33/297 [11.1%]; <span class="elsevierStyleItalic">P</span><span class="elsevierStyleHsp" style=""></span><<span class="elsevierStyleHsp" style=""></span>.05).</p><p id="par0040" class="elsevierStylePara elsevierViewall">The percentage of the total of unintentional acute paediatric poisonings associated with inappropriate storage was not insignificant, especially for poisonings involving household products.</p><p id="par0045" class="elsevierStylePara elsevierViewall">In spite of preventive campaigns, up to 15% of unintentional acute poisonings result from the ingestion of products stored in non-original containers. Our study raises a red flag on the frequency of this type of poisonings, even though it is rare for them to be studied specifically.<a class="elsevierStyleCrossRefs" href="#bib0040"><span class="elsevierStyleSup">3,4</span></a> While there is no evidence on the impact of health education on the prognosis of acute paediatric poisonings,<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">5</span></a> we believe that it is important to inform the population and paediatricians on this type of unintentional poisonings. These poisonings are particularly common in patients aged more than 4 years, in whom more than 90% of poisonings with household products are associated with inappropriate storage, especially of caustic substances. This fact may be related to the inappropriate habit of adults of storing such toxic substances in containers as common as plastic bottles, which children associate with harmless contents.</p><p id="par0050" class="elsevierStylePara elsevierViewall">One salient finding of our study was the characteristics of medication poisonings related to inappropriate storage. The percentage of combined drug intoxications was significantly higher in these patients. The fact that such poisonings occur in the parents’ bedroom and frequently involve benzodiazepines emphasises the need to improve health education efforts in our population.</p><p id="par0055" class="elsevierStylePara elsevierViewall">There are various limitations to our study. The prospective register did not document the type of container used by families to store the substances involved in the poisonings. This information would be helpful to design more specific preventive interventions, although its absence did not compromise the aims of the study.</p><p id="par0060" class="elsevierStylePara elsevierViewall">While this type of storage is not associated with a potentially greater severity in poisoning cases, preventive strategies should contemplate providing health education on the storage and conservation of household products.</p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Bilbao N, Santiago P, Azkunaga B, Mintegi S. Intoxicaciones agudas no intencionadas asociadas a recipientes no originales. An Pediatr (Barc). 2016;85:102–104.</p>" ] ] "apendice" => array:1 [ 0 => array:1 [ "seccion" => array:1 [ 0 => array:4 [ "apendice" => "<p id="par0065" class="elsevierStylePara elsevierViewall">H. Alto Deba: Agustín Rodríguez; H. del Tajo, Aranjuez: Carlos García-Vao; H.U. Arnau de Vilanova, Lleida: Neus Pociello; H.U. Basurto: Javier Humayor; H. Cabueñes: Ramón Fernández; H.U. Carlos Haya: Silvia Oliva Rodríguez-Pastor; Complejo Hospitalario de Jaén: Tomás del Campo; C. Asistencial Universitario de León: Ana Gloria Andrés; Corporación Sanitaria Parc Taulí, Sabadell: Mireia Pérez; H.U. Cruces: Paula Santiago, Nerea Bilbao; H.U. Doce de Octubre: Sofía Mesa; H.U. Donostia: José Angel Muñoz Bernal; H.U. Dr. Peset. Valencia: J. Rafael Bretón Martínez; H.U. Fuenlabrada: Rocío Rodríguez; H. Francesc de Borja de Gandía: Carlos Miguel Angelats; Fundació Sant Hospital de la Seu d’Urgell: Pablo Javier Ercoli; H. Universitario Fundación Alcorcón: Alberto Barasoain; H. General Universitario de Alicante: Olga Gómez Pérez; H.U. Gregorio Marañón: Paula Vázquez; H. Infanta Cristina, Parla, Madrid: Begoña de Miguel; H. de Terrassa: Judit Barrena; H. Laredo: Ana Jorda; H.U. Lucus Augusti: Sandra Yáñez; H. Mendaro: Laura Herrero; H.U. Mutua Terrassa: Elena May Llanas; H.U. Niño Jesús: Juan Carlos Molina; H. Materno-infantil de Las Palmas de Gran Canaria: Lily Mangione; H. Materno-infantil de Badajoz: Paz Hurtado; H. Ntra. Sra. de Sonsoles, Ávila: Helvia Benito; H. Montepríncipe, H. Sanchinarro, H. Torrelodones, Madrid: Silvina Natalini; H. Príncipe de Asturias, Alcalá de Henares: M. Angeles García Herrero; H.U. Puerta de Hierro Majadahonda: Consuelo Benito Caldés; H. Rey Juan Carlos: Pablo Bello Gutiérrez; H.U. San Agustín: Juan Cózar Olmo; H.U. Río Hortega, Valladolid: Roberto Velasco; H. Sant Joan de Déu, Xarxa Hospitalaria i Universitaria de Manresa. Fundació Althaia: Eva Botifoll García; H.U. Sant Joan de Déu: Lidia Martínez Sánchez; H. Sant Joan de Reus: María Rimblas; H. San Pedro: Laura Martínez; H. Miguel Servet: Carmen Campos Calleja; H.U. Son Espases, Palma de Mallorca: Victoria López Corominas; H. Son Llàtzer: Carmen Vidal Palacios; H.U. Central de Asturias, Oviedo: Julián Rodríguez; H. Universitario de Salamanca: Javier López Ávila; H.U. Virgen de la Arrixaca: Carlos Pérez; H. Virgen de la Salud, Toledo: Esther Crespo Rupérez; Complejo Hospitalario de Navarra: Miriam Palacios; H. Zumarraga: Amalia Pérez; Fundación H. de Nens, Barcelona: Amalia Arce Casas; H. Quirón, Bizkaia: Itziar Iturralde; H. Clínico U. Lozano Blesa: Gonzalo González García; H.U. Puerta del Mar, Cadiz: Arturo Hernández; H. Clínico U. de Valladolid: Elena Urbaneja Rodríguez; Complejo Asistencial de Segovia: H. General: Rebeca Garrote; H.U. y Politécnico La Fe de Valencia: Rafael Señer; Hospital de Mataró: Joaquim Martorell Aymerich; H.U. Marqués de Valdecilla: José Lorenzo Guerra; H. Sierrallana: José Lorenzo Guerra; H. Gernika-Lumo: Alicia Gutiérrez.</p>" "etiqueta" => "Appendix 1" "titulo" => "Centres participating in and responsible for the Toxicology Surveillance System" "identificador" => "sec0005" ] ] ] ] "multimedia" => array:1 [ 0 => array:8 [ "identificador" => "tbl0005" "etiqueta" => "Table 1" "tipo" => "MULTIMEDIATABLA" "mostrarFloat" => true "mostrarDisplay" => false "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at1" "detalle" => "Table " "rol" => "short" ] ] "tabla" => array:1 [ "tablatextoimagen" => array:1 [ 0 => array:2 [ "tabla" => array:1 [ 0 => """ <table border="0" frame="\n \t\t\t\t\tvoid\n \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head " align="" valign="top" scope="col" style="border-bottom: 2px solid black"> \t\t\t\t\t\t\n \t\t\t\t</th><th class="td" title="table-head " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Original container (143) \t\t\t\t\t\t\n \t\t\t\t</th><th class="td" title="table-head " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Non-original container (57) \t\t\t\t\t\t\n \t\t\t\t</th><th class="td" title="table-head " align="left" valign="top" scope="col" style="border-bottom: 2px solid black"><span class="elsevierStyleItalic">P</span> \t\t\t\t\t\t\n \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td" title="table-entry " colspan="4" align="left" valign="top"><span class="elsevierStyleItalic">Age</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; 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entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Caustic ingestion</span> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">26; 18.1% \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">25; 43.8% \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top"><.001 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Diagnostic testing</span> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">45; 31.5% \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">22; 38.6% \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">n.s. \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Treatments</span> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">54; 37.8% \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">22; 38.6% \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">n.s. \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Admission to hospital</span> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">13; 9.1% \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">8; 14.0% \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">n.s. \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Admission to PICU</span> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">0 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">1; 1.8% \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">n.s. \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Sequelae</span> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">0 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">1; 1.8% \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">n.s. \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Death</span> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">0 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">0 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">n.s. \t\t\t\t\t\t\n \t\t\t\t</td></tr></tbody></table> """ ] "imagenFichero" => array:1 [ 0 => "xTab1144657.png" ] ] ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Characteristics of unintentional acute poisonings with household products by type of storage.</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:5 [ 0 => array:3 [ "identificador" => "bib0030" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Grupo de Trabajo de Intoxicaciones de la Sociedad Española de Urgencias de Pediatría. 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Year/Month | Html | Total | |
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2024 November | 4 | 7 | 11 |
2024 October | 31 | 39 | 70 |
2024 September | 37 | 26 | 63 |
2024 August | 60 | 56 | 116 |
2024 July | 29 | 24 | 53 |
2024 June | 44 | 26 | 70 |
2024 May | 32 | 37 | 69 |
2024 April | 36 | 36 | 72 |
2024 March | 31 | 17 | 48 |
2024 February | 27 | 35 | 62 |
2024 January | 36 | 22 | 58 |
2023 December | 21 | 16 | 37 |
2023 November | 24 | 30 | 54 |
2023 October | 32 | 25 | 57 |
2023 September | 28 | 21 | 49 |
2023 August | 19 | 15 | 34 |
2023 July | 35 | 31 | 66 |
2023 June | 29 | 29 | 58 |
2023 May | 33 | 23 | 56 |
2023 April | 17 | 1915 | 1932 |
2023 March | 23 | 18 | 41 |
2023 February | 21 | 15 | 36 |
2023 January | 18 | 29 | 47 |
2022 December | 39 | 23 | 62 |
2022 November | 42 | 23 | 65 |
2022 October | 33 | 44 | 77 |
2022 September | 22 | 33 | 55 |
2022 August | 27 | 38 | 65 |
2022 July | 19 | 40 | 59 |
2022 June | 23 | 29 | 52 |
2022 May | 24 | 33 | 57 |
2022 April | 24 | 38 | 62 |
2022 March | 36 | 35 | 71 |
2022 February | 25 | 24 | 49 |
2022 January | 19 | 31 | 50 |
2021 December | 25 | 38 | 63 |
2021 November | 30 | 53 | 83 |
2021 October | 39 | 66 | 105 |
2021 September | 30 | 29 | 59 |
2021 August | 25 | 39 | 64 |
2021 July | 15 | 16 | 31 |
2021 June | 28 | 28 | 56 |
2021 May | 29 | 46 | 75 |
2021 April | 45 | 79 | 124 |
2021 March | 35 | 36 | 71 |
2021 February | 31 | 15 | 46 |
2021 January | 25 | 29 | 54 |
2020 December | 21 | 23 | 44 |
2020 November | 22 | 18 | 40 |
2020 October | 17 | 14 | 31 |
2020 September | 24 | 23 | 47 |
2020 August | 19 | 18 | 37 |
2020 July | 16 | 22 | 38 |
2020 June | 12 | 11 | 23 |
2020 May | 23 | 19 | 42 |
2020 April | 14 | 17 | 31 |
2020 March | 24 | 10 | 34 |
2020 February | 32 | 14 | 46 |
2020 January | 21 | 24 | 45 |
2019 December | 31 | 21 | 52 |
2019 November | 8 | 8 | 16 |
2019 October | 15 | 7 | 22 |
2019 September | 19 | 9 | 28 |
2019 August | 17 | 13 | 30 |
2019 July | 21 | 31 | 52 |
2019 June | 23 | 22 | 45 |
2019 May | 37 | 14 | 51 |
2019 April | 33 | 16 | 49 |
2019 March | 23 | 23 | 46 |
2019 February | 32 | 11 | 43 |
2019 January | 35 | 15 | 50 |
2018 December | 26 | 32 | 58 |
2018 November | 105 | 26 | 131 |
2018 October | 56 | 20 | 76 |
2018 September | 30 | 15 | 45 |
2018 July | 2 | 0 | 2 |
2018 June | 3 | 0 | 3 |
2018 May | 11 | 0 | 11 |
2018 April | 18 | 0 | 18 |
2018 March | 12 | 0 | 12 |
2018 February | 13 | 0 | 13 |
2018 January | 22 | 0 | 22 |
2017 December | 11 | 0 | 11 |
2017 November | 8 | 0 | 8 |
2017 October | 14 | 0 | 14 |
2017 September | 12 | 0 | 12 |
2017 August | 15 | 0 | 15 |
2017 July | 27 | 2 | 29 |
2017 June | 17 | 7 | 24 |
2017 May | 18 | 9 | 27 |
2017 April | 12 | 7 | 19 |
2017 March | 11 | 2 | 13 |
2017 February | 13 | 13 | 26 |
2017 January | 10 | 0 | 10 |
2016 December | 26 | 18 | 44 |
2016 November | 30 | 16 | 46 |
2016 October | 20 | 22 | 42 |
2016 September | 48 | 12 | 60 |
2016 August | 71 | 14 | 85 |
2016 July | 25 | 7 | 32 |