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Vol. 58. Núm. 2.
Páginas 156-161 (febrero 2003)
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Vol. 58. Núm. 2.
Páginas 156-161 (febrero 2003)
Acceso a texto completo
Retinopatía del prematuro: incidencia, gravedad y evolución
Retinopathy of prematurity: incidence,severity and outcome
Visitas
12665
N. Martín Beguéa,
Autor para correspondencia
nmartin@cs.vhebron.es

Correspondencia: Unidad de Oftalmología Pediátrica. Hospital Vall d’Hebron.P.º Vall d’Hebron, 119-129. 08035 Barcelona. España
, J. Perapoch Lópezb
a Unidad de Oftalmología Pediátrica
b Servicio de Neonatología. Hospital Vall dHebron. Barcelona. España
Este artículo ha recibido
Información del artículo
Objetivo

Determinar la incidencia, gravedad y evolución de la retinopatía del prematuro en recién nacidos con peso inferior a 1.501 g en nuestro medio.

Métodos

Se ha efectuado un estudio prospectivo de los recién nacidos de peso inferior a 1.501 g entre enero de 1999 y junio de 2000. Se han incluido en el estudio 178 pacientes con una edad gestacional media de 29,8 6 2,9 semanas y peso medio de 1.095 6 261,5 g.

Resultados

Desarrollaron retinopatía el 29,2% de los recién nacidos, de los cuales 5,6% presentaron una retinopatía en estadio umbral y precisaron tratamiento. Ningún paciente de más de 30 semanas o más de 1.250 g presentó una retinopatía grave.

Conclusiones

La incidencia es similar a la publicada en la literatura, y la inmadurez es el principal factor de riesgo de desarrollar la retinopatía. Los resultados del estudio nos ha hecho variar el programa de cribado para detectar todos los prematuros con retinopatía del prematuro en estadio umbral.

Palabras clave:
Retinopatía del prematuro
Pérdida de visión
Prematuridad
Objective

The aim of this study was to evaluate the incidence, severity and outcome of retinopathy of prematurity (ROP) in neonates with birth weights of less than 1,501 g in our environment

Methods

A prospective study of infants with birth weights of less than 1,501 g was performed from January 1999 to June 2000. One hundred seventy-eight infants were enrolled in the study. Mean gestational age was 29.8 6 2.9 weeks and mean birth weight was 1,095 6 261.5 g.

Results

Overall, 52 infants (29.2 %) developed ROP, of which 10 (5.6 %) presented threshold ROP requiring treatment. None of the infants with a gestational age of more than 30 weeks and a birth weight of more than 1,250 g presented severe retinopathy.

Conclusions

The incidence found in the present study is similar to that of other studies. Immaturity is the most significant risk factors for the development of ROP. The results of our study led us to change our screening program to detect all threshold ROP.

Key words:
Retinopathy of prematurity
Loss of vision
Prematurity
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Bibliografía
[1.]
G. Holmstrom, U. Broberger, P. Thomassen.
Neonatal risk factors for retinopathy of prematurity a population based study.
Acta Ophthalmol Scand, 76 (1998), pp. 204-207
[2.]
J.L. Olea, F.J. Corretger, M. Salvat, E. Frau, C. Galiana, M. Fiol.
Factores de riesgo en la retinopatía del prematuro.
An Esp Pediatr, 47 (1997), pp. 172-176
[3.]
Cryotherapy for Retinopathy of Prematurity Cooperative Group. Multicenter trial of criotherapy for retinopathy of prematurity: Preliminary results.
Arch Ophthalmol, 106 (1988), pp. 471-479
[4.]
Cryotherapy for Retinopathy of Prematurity Cooperative Group. Multicenter trial of criotherapy for retinopathy of prematurity: Three-month outcome.
Arch Ophthalmol, 108 (1990), pp. 195-204
[5.]
I.A. Pearce, F.C. Pennie, L.M. Gannon, A.M. Weindling, D.I. Clark.
Three year visual outcome for treated stage 3 retinopathy of prematurity: Cryotherapy versus laser.
Br J Ophthalmol, 82 (1998), pp. 1254-1259
[6.]
B.W. Fleck.
Therapy for retinopathy of prematurity.
[7.]
M.H. DeJonge, P.J. Ferrone, M.T. Trese.
Diodo laser ablation for threshold retinopathy of prematurity.
Arch Ophthalmol, 118 (2000), pp. 365-367
[8.]
Committe for the Classification of Retinopathy of Prematurity: The International Classification of Retinopathy of Prematurity.
Arch Ophthalmol, 102 (1984), pp. 1130-1134
[9.]
The International Committee for the Classification of the Late Stages of Retinopathy of Prematurity. An International Classification of Retinopathy of Prematurity: The classification of retinal detachment.
Arch Ophthalmol, 105 (1987), pp. 906-912
[10.]
J. Lim, D.S. Fong, Y. Dang.
Decreased prevalence of retinopathy of prematurity in an inner-city hospital.
Ophthalmic Surg Lasers, 30 (1999), pp. 12-16
[11.]
J. Termote, N.E. Schalij-Delfos, H.A.A. Brouwers, A.R.T. Donders, B.P. Cats.
New developments in neonatology: Less severe retinopathy of prematurity.
J Pediatr Ophthalmol Strabismus, 37 (2000), pp. 142-148
[12.]
E. Bossi, F. Koerner.
Retinopathy of prematurity.
Intensive Care Med, 21 (1995), pp. 241-246
[13.]
C.R. Pallás, P. Tejada, M.C. Medina, M.J. Martín, C. Orbea, M.C. Barrios.
Retinopatía del prematuro: nuestra experiencia.
An Esp Pediatr, 42 (1995), pp. 52-56
[14.]
G. Holmstrom, M. El Azazi, L. Jacobson, G. Lennerstrand.
A population based, prospective study of the development of ROP in prematurely born children in the Stockholm area of Sweden.
Br J Ophthalmol, 77 (1993), pp. 417-423
[15.]
E.A. Palmer, J.T. Flynn, R.J. Hardy, D.L. Phelps, C.L. Phillips, D.B. Schaffer.
Incidence and early course of retinopathy of prematurity. The Cryotherapy for Retinopathy of Prematurity Cooperative Group.
Ophthalmology, 98 (1991), pp. 1628-1640
[16.]
M.J. Párraga, R. Sánchez, J.C. Barreiro, R. Canete, F. Fernández, M. Zapatero.
Retinopatía del prematuro. Resultados tras un año de seguimiento.
An Esp Pediatr, 44 (1996), pp. 482-484
[17.]
Y.K. Ng, D.W. Shaw, A.R. Fielder, M.I. Levene.
Epidemiology of retinopathy of prematurity.
Lancet, 26 (1988), pp. 1235-1238
[18.]
M.X. Repka, E.A. Palmer, B. Tung.
Involution of retinopathy of prematurity.
Arch Ophthalmol, 118 (2000), pp. 645-649
[19.]
F.J. De la Cruz Bértolo, C.R. Pallás Alonso, P. Tejada Palacios.
Cribado para la retinopatía de la prematuridad: ni son todos los que están, ni están todos los que son.
An Esp Pediatr, 50 (1999), pp. 156-160
[20.]
S.K. Lee, C. Normand, D. McMillan, A. Ohlsson, M. Vincer, C. Lyons.
. Evidence for changing guidelines for routine screening for retinopathy of prematurity.
Arch Pediatr Adolesc Med, 155 (2001), pp. 387-395
[21.]
Royal College of Ophthalmologists British Association of Perinatal Medicine, (1995),
[22.]
American Academy of Pediatrics, the American Association for Pediatric Ophthalmology and Strabismus, and the American Academy of Ophthalmology. Screening examination of premature infants for retinopathy of prematurity.
Ophthalmology, 104 (1997), pp. 888-889
[23.]
I. Nissenkorn, I. Kremer, E. Gilad.
Rush type retinopathy of prematurity, report of three cases.
Br J Ophthalmol, 71 (1987), pp. 559-562
[24.]
O.D. Saugstad.
Oxygen radical disease in neonatology.
Semin Neonatol, 3 (1998), pp. 229-238
[25.]
V.E. Kinsey, J.T. Jacobs, F.M. Hemphill.
Retrolental fibroplasia: Cooperative study of retrolental fibroplasia and the use of oxygen.
Arch Ophthalmol, 56 (1956), pp. 481-547
[26.]
The STOP-ROP Multicenter Study Group. Supplemental therapeutic oxygen for prethreshold retinopathy of prematurity (STOP-ROP), a randomized, controlled trial. I: Primary outcomes.
Pediatrics, 105 (2000), pp. 295-310
[27.]
X. Gu, S. Samuel, M. El-Shabrawey, R.B. Caldwell, M. Bartoli, D.M. Marcus.
Effects of sustained hyperoxia on revascularization in experimental retinopathy of prematurity.
Invest Ophthalmol Vis Sci, 43 (2002), pp. 496-502
[28.]
G. Holmstrom, M. El Azazi, U. Kugelberg.
Ophthalmological long term follow up of preterm infants: A population based, prospective study of the refraction and its development.
Br J Ophthalmol, 82 (1998), pp. 1265-1271
[29.]
B. Ricci.
Refractive errors and ocular motility disorders in preterm babies with and without retinopathy of prematurity.
Ophthalmologica, 213 (1999), pp. 295-299
Copyright © 2003. Asociación Española de Pediatría
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