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        "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p class="elsevierStyleSimplePara elsevierViewall">Estimar la incidencia de rinitis al&#233;rgica en poblaci&#243;n escolar de Castell&#243;n al comparar las fases I y III del International Study of Asthma and Allergies in Childhood &#40;ISAAC&#41;&#44; efectuadas en 1994 y 2002&#44; respectivamente&#46;</p> <span class="elsevierStyleSectionTitle">Material y m&#233;todos</span><p class="elsevierStyleSimplePara elsevierViewall">Se estudi&#243; una cohorte de 3&#46;607 escolares que participaron en la fase I &#40;grupo de 6 y 7 a&#241;os&#41;&#46; De ellos&#44; 8 a&#241;os m&#225;s tarde&#44; participaron en la fase III 1&#46;805 &#40;grupo de 14 y 15 a&#241;os&#41;&#44; con 1&#46;627 escolares sin rinitis al&#233;rgica en la fase I&#46; Se estim&#243; la incidencia acumulada de rinitis al&#233;rgica&#46; Se utilizaron dos definiciones como caso nuevo de rinitis al&#233;rgica&#44; la primera por diagn&#243;stico o tratamiento m&#233;dico de la rinitis al&#233;rgica y la segunda incluyendo&#44; adem&#225;s&#44; s&#237;ntomas en los &#250;ltimos 12 meses&#46; Se calcul&#243; el riesgo relativo mediante modelos de regresi&#243;n de Poisson&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">La participaci&#243;n alcanz&#243; el 50 &#37; y se detectaron 151 casos nuevos de rinitis al&#233;rgica seg&#250;n la primera definici&#243;n &#40;incidencia acumulada 9&#44;3 y 1&#44;2 &#37; anual&#41;&#44; y 339 casos nuevos con la segunda definici&#243;n &#40;incidencia acumulada 20&#44;8 y 2&#44;6 &#37; anual&#41;&#46; No se observaron diferencias por sexo para la primera definici&#243;n &#40;riesgo relativo RR&#93;&#58; 1&#44;00&#59; intervalo de confianza del 95 &#37; &#91;IC 95&#37;&#93;&#58; 0&#44;73-1&#44;38&#41;&#44; pero con la segunda definici&#243;n las mujeres tuvieron mayor incidencia &#40;RR&#58; 1&#44;46&#59; IC 95 &#37;&#58; 1&#44;18-1&#44;82&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">La incidencia acumulada de rinitis al&#233;rgica seg&#250;n la primera definici&#243;n fue comparable a las estimadas en estudios de cohorte de poblaciones adolescentes&#46;</p>"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p class="elsevierStyleSimplePara elsevierViewall">To estimate the incidence of allergic rhinitis in schoolchildren in Castell&#243;n by comparing phases I and III of the International Study of Asthma and Allergies in Childhood &#40;ISAAC&#41;&#44; carried out in 1994 and 2002&#44; respectively&#46;</p> <span class="elsevierStyleSectionTitle">Material and methods</span><p class="elsevierStyleSimplePara elsevierViewall">A cohort study was performed with 3607 schoolchildren aged 6-7 years old who participated in phase I of the ISAAC study&#46; Of these&#44; 1805 participated in phase III &#40;8 years later&#41; at the age of 14-15 years&#44; with 1627 schoolchildren without allergic rhinitis in phase I&#46; The cumulative incidence of allergic rhinitis was estimated&#46; Two definitions of new cases of allergic rhinitis were used&#58; the first was based on medical diagnosis or treatment of the disease&#44; and the second also included symptoms of allergic rhinitis in the previous 12 months&#46; Relative risks were calculated using Poisson regression&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">Participation was 50&#46;0&#37;&#44; and 151 new cases of allergic rhinitis according to the first definition &#40;cumulative incidence of 9&#46;3&#37; and 1&#46;2&#37; per year&#41; and 339 new cases according to the second definition &#40;cumulative incidence of 20&#46;8 &#37; and 2&#46;6&#37; per year&#41; were found&#46; No differences in incidence by gender were observed with the first definition &#40;RR &#61; 1&#46;00 95 &#37; CI 0&#46;73-1&#46;38&#41; but with the second definition&#44; the incidence was greater in girls &#40;RR &#61; 1&#46;46 95&#37; CI 1&#46;18-1&#46;82&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">The cumulative incidence of allergic rhinitis according to the first definition was in the range of incidence from cohort studies of adolescents&#46;</p>"
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Originales
Incidencia de rinitis alérgica en escolares entre 1994 y 2002 en Castellón según el estudio ISAAC
Incidence of allergic rhinitis in a cohort of schoolchildren between 1994 and 2002 in Castellón (Spain), following the isaac study
E. Tornador-Gayaa, R. Tosca-Seguraa, A. Arnedo-Penab,
Autor para correspondencia
arnedo_alb@gva.es

Correspondencia: Dr. A. Arnedo-Pena. Sección de Epidemiología. Centro Salud Pública. L’Olivera, 5, 2-C. 12005 Castellón. España.
, J. Puig-Barberác, J.B. Bellido-Blascob, M.ªR. Pac-Sad, A. Artero-Civerae, J.B. Campos-Cruañesf, L. Museros-Recatalab
a Servicio de Pediatría. Hospital General. Castellón
b Sección de Epidemiología. Centro Salud Pública. Castellón
c Unidad de Programas. Centro Salud Pública. Castellón
d Sección de Ordenación Sanitaria. Dirección Territorial de Sanidad. Castellón
e Centro de Salud. Burriana
f SAMU de L’Alcora. Conselleria de Sanitat. Castellón. España
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        "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p class="elsevierStyleSimplePara elsevierViewall">Estimar la incidencia de rinitis al&#233;rgica en poblaci&#243;n escolar de Castell&#243;n al comparar las fases I y III del International Study of Asthma and Allergies in Childhood &#40;ISAAC&#41;&#44; efectuadas en 1994 y 2002&#44; respectivamente&#46;</p> <span class="elsevierStyleSectionTitle">Material y m&#233;todos</span><p class="elsevierStyleSimplePara elsevierViewall">Se estudi&#243; una cohorte de 3&#46;607 escolares que participaron en la fase I &#40;grupo de 6 y 7 a&#241;os&#41;&#46; De ellos&#44; 8 a&#241;os m&#225;s tarde&#44; participaron en la fase III 1&#46;805 &#40;grupo de 14 y 15 a&#241;os&#41;&#44; con 1&#46;627 escolares sin rinitis al&#233;rgica en la fase I&#46; Se estim&#243; la incidencia acumulada de rinitis al&#233;rgica&#46; Se utilizaron dos definiciones como caso nuevo de rinitis al&#233;rgica&#44; la primera por diagn&#243;stico o tratamiento m&#233;dico de la rinitis al&#233;rgica y la segunda incluyendo&#44; adem&#225;s&#44; s&#237;ntomas en los &#250;ltimos 12 meses&#46; Se calcul&#243; el riesgo relativo mediante modelos de regresi&#243;n de Poisson&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">La participaci&#243;n alcanz&#243; el 50 &#37; y se detectaron 151 casos nuevos de rinitis al&#233;rgica seg&#250;n la primera definici&#243;n &#40;incidencia acumulada 9&#44;3 y 1&#44;2 &#37; anual&#41;&#44; y 339 casos nuevos con la segunda definici&#243;n &#40;incidencia acumulada 20&#44;8 y 2&#44;6 &#37; anual&#41;&#46; No se observaron diferencias por sexo para la primera definici&#243;n &#40;riesgo relativo RR&#93;&#58; 1&#44;00&#59; intervalo de confianza del 95 &#37; &#91;IC 95&#37;&#93;&#58; 0&#44;73-1&#44;38&#41;&#44; pero con la segunda definici&#243;n las mujeres tuvieron mayor incidencia &#40;RR&#58; 1&#44;46&#59; IC 95 &#37;&#58; 1&#44;18-1&#44;82&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">La incidencia acumulada de rinitis al&#233;rgica seg&#250;n la primera definici&#243;n fue comparable a las estimadas en estudios de cohorte de poblaciones adolescentes&#46;</p>"
      ]
      "en" => array:1 [
        "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p class="elsevierStyleSimplePara elsevierViewall">To estimate the incidence of allergic rhinitis in schoolchildren in Castell&#243;n by comparing phases I and III of the International Study of Asthma and Allergies in Childhood &#40;ISAAC&#41;&#44; carried out in 1994 and 2002&#44; respectively&#46;</p> <span class="elsevierStyleSectionTitle">Material and methods</span><p class="elsevierStyleSimplePara elsevierViewall">A cohort study was performed with 3607 schoolchildren aged 6-7 years old who participated in phase I of the ISAAC study&#46; Of these&#44; 1805 participated in phase III &#40;8 years later&#41; at the age of 14-15 years&#44; with 1627 schoolchildren without allergic rhinitis in phase I&#46; The cumulative incidence of allergic rhinitis was estimated&#46; Two definitions of new cases of allergic rhinitis were used&#58; the first was based on medical diagnosis or treatment of the disease&#44; and the second also included symptoms of allergic rhinitis in the previous 12 months&#46; Relative risks were calculated using Poisson regression&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">Participation was 50&#46;0&#37;&#44; and 151 new cases of allergic rhinitis according to the first definition &#40;cumulative incidence of 9&#46;3&#37; and 1&#46;2&#37; per year&#41; and 339 new cases according to the second definition &#40;cumulative incidence of 20&#46;8 &#37; and 2&#46;6&#37; per year&#41; were found&#46; No differences in incidence by gender were observed with the first definition &#40;RR &#61; 1&#46;00 95 &#37; CI 0&#46;73-1&#46;38&#41; but with the second definition&#44; the incidence was greater in girls &#40;RR &#61; 1&#46;46 95&#37; CI 1&#46;18-1&#46;82&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">The cumulative incidence of allergic rhinitis according to the first definition was in the range of incidence from cohort studies of adolescents&#46;</p>"
      ]
    ]
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                        ]
                      ]
                    ]
                  ]
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                    0 => array:1 [
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                        "fecha" => "1999"
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                0 => array:2 [
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                        0 => array:2 [
                          "etal" => true
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                          "etal" => true
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                            0 => "T&#46; McKeever"
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                  ]
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                        ]
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                    ]
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                ]
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            ]
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            ]
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                        0 => array:2 [
                          "etal" => false
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                            1 => "C&#46; Holberg"
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                          ]
                        ]
                      ]
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                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
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                          ]
                        ]
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                ]
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            ]
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                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "P&#46; Nafstad"
                            1 => "B&#46; Brunekreef"
                            2 => "A&#46; Skrondal"
                            3 => "W&#46; Nystad"
                          ]
                        ]
                      ]
                    ]
                  ]
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ISSN: 16954033
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