array:23 [
  "pii" => "S1695403307703211"
  "issn" => "16954033"
  "doi" => "10.1157/13098930"
  "estado" => "S300"
  "fechaPublicacion" => "2007-02-01"
  "aid" => "70321"
  "copyright" => "Asociación Española de Pediatría"
  "copyrightAnyo" => "2007"
  "documento" => "article"
  "crossmark" => 0
  "subdocumento" => "fla"
  "cita" => "An Pediatr (Barc). 2007;66:135-9"
  "abierto" => array:3 [
    "ES" => false
    "ES2" => false
    "LATM" => false
  ]
  "gratuito" => false
  "lecturas" => array:2 [
    "total" => 7153
    "formatos" => array:3 [
      "EPUB" => 79
      "HTML" => 6449
      "PDF" => 625
    ]
  ]
  "itemSiguiente" => array:18 [
    "pii" => "S1695403307703223"
    "issn" => "16954033"
    "doi" => "10.1157/13098931"
    "estado" => "S300"
    "fechaPublicacion" => "2007-02-01"
    "aid" => "70322"
    "copyright" => "Asociación Española de Pediatría"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "fla"
    "cita" => "An Pediatr (Barc). 2007;66:140-5"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:2 [
      "total" => 6812
      "formatos" => array:3 [
        "EPUB" => 79
        "HTML" => 5736
        "PDF" => 997
      ]
    ]
    "es" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Originales</span>"
      "titulo" => "Utilidad del CRIB para predecir la muerte hospitalaria y la hemorragia intraventricular en los prematuros de muy bajo peso y extremado bajo peso al nacer"
      "tienePdf" => "es"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "es"
        1 => "en"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "140"
          "paginaFinal" => "145"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "en" => array:1 [
          "titulo" => "Utility of the clinical risk index for babies &#40;CRIB&#41; as a predictor of hospital death and intraventricular hemorrhage in very low birth weight and extremely low birth weight neonates"
        ]
      ]
      "contieneResumen" => array:2 [
        "es" => true
        "en" => true
      ]
      "contienePdf" => array:1 [
        "es" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "R&#46; Rivas Ruiz, J&#46;M&#46;&#170; Guzm&#225;n Caba&#241;as, M&#46;&#170;J&#46; P&#225;rraga Quiles, M&#46;&#170;D&#46; Ruiz Gonz&#225;lez, M&#46;&#170;D&#46; Huertas Mu&#241;oz, R&#46; &#193;lvarez Marcos, M&#46; Zapatero Mart&#237;nez"
          "autores" => array:7 [
            0 => array:2 [
              "nombre" => "R&#46;"
              "apellidos" => "Rivas Ruiz"
            ]
            1 => array:2 [
              "nombre" => "J&#46;M&#46;&#170;"
              "apellidos" => "Guzm&#225;n Caba&#241;as"
            ]
            2 => array:2 [
              "nombre" => "M&#46;&#170;J&#46;"
              "apellidos" => "P&#225;rraga Quiles"
            ]
            3 => array:2 [
              "nombre" => "M&#46;&#170;D&#46;"
              "apellidos" => "Ruiz Gonz&#225;lez"
            ]
            4 => array:2 [
              "nombre" => "M&#46;&#170;D&#46;"
              "apellidos" => "Huertas Mu&#241;oz"
            ]
            5 => array:2 [
              "nombre" => "R&#46;"
              "apellidos" => "&#193;lvarez Marcos"
            ]
            6 => array:2 [
              "nombre" => "M&#46;"
              "apellidos" => "Zapatero Mart&#237;nez"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "es"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1695403307703223?idApp=UINPBA00005H"
    "url" => "/16954033/0000006600000002/v2_201308271339/S1695403307703223/v2_201308271339/es/main.assets"
  ]
  "itemAnterior" => array:18 [
    "pii" => "S169540330770320X"
    "issn" => "16954033"
    "doi" => "10.1157/13098929"
    "estado" => "S300"
    "fechaPublicacion" => "2007-02-01"
    "aid" => "70320"
    "copyright" => "Asociaci&#243;n Espa&#241;ola de Pediatr&#237;a"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "fla"
    "cita" => "An Pediatr &#40;Barc&#41;. 2007;66:129-34"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:2 [
      "total" => 8765
      "formatos" => array:3 [
        "EPUB" => 92
        "HTML" => 7731
        "PDF" => 942
      ]
    ]
    "es" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Originales</span>"
      "titulo" => "Tics en ni&#241;os y adolescentes&#58; an&#225;lisis retrospectivo de 78 casos"
      "tienePdf" => "es"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "es"
        1 => "en"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "129"
          "paginaFinal" => "134"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "en" => array:1 [
          "titulo" => "Tics in children and adolescents&#58; a retrospective analysis of 78 cases"
        ]
      ]
      "contieneResumen" => array:2 [
        "es" => true
        "en" => true
      ]
      "contienePdf" => array:1 [
        "es" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "A&#46; Catarina Prior, S&#46; Tavares, S&#46; Figueiroa, T&#46; Temudo"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "A&#46;"
              "apellidos" => "Catarina Prior"
            ]
            1 => array:2 [
              "nombre" => "S&#46;"
              "apellidos" => "Tavares"
            ]
            2 => array:2 [
              "nombre" => "S&#46;"
              "apellidos" => "Figueiroa"
            ]
            3 => array:2 [
              "nombre" => "T&#46;"
              "apellidos" => "Temudo"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "es"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S169540330770320X?idApp=UINPBA00005H"
    "url" => "/16954033/0000006600000002/v2_201308271339/S169540330770320X/v2_201308271339/es/main.assets"
  ]
  "es" => array:15 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Originales</span>"
    "titulo" => "Seroprevalencia de la infecci&#243;n por citomegalovirus en pu&#233;rperas y su impacto neonatal"
    "tieneTextoCompleto" => 0
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "135"
        "paginaFinal" => "139"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "D&#46; Estripeaut, Y&#46; Moreno, S&#46; Ahumada Ruiz, A&#46; Mart&#237;nez, J&#46;D&#46; Racine, X&#46; S&#225;ez-Llorens"
        "autores" => array:6 [
          0 => array:4 [
            "nombre" => "D&#46;"
            "apellidos" => "Estripeaut"
            "email" => array:1 [
              0 => "destripeaut&#64;yahoo&#46;com"
            ]
            "referencia" => array:2 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff1"
              ]
              1 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">¿</span>"
                "identificador" => "cor1"
              ]
            ]
          ]
          1 => array:3 [
            "nombre" => "Y&#46;"
            "apellidos" => "Moreno"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">b</span>"
                "identificador" => "aff2"
              ]
            ]
          ]
          2 => array:3 [
            "nombre" => "S&#46;"
            "apellidos" => "Ahumada Ruiz"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">c</span>"
                "identificador" => "aff3"
              ]
            ]
          ]
          3 => array:3 [
            "nombre" => "A&#46;"
            "apellidos" => "Mart&#237;nez"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">c</span>"
                "identificador" => "aff3"
              ]
            ]
          ]
          4 => array:3 [
            "nombre" => "J&#46;D&#46;"
            "apellidos" => "Racine"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">d</span>"
                "identificador" => "aff4"
              ]
            ]
          ]
          5 => array:3 [
            "nombre" => "X&#46;"
            "apellidos" => "S&#225;ez-Llorens"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff1"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:4 [
          0 => array:3 [
            "entidad" => "Servicio de Infectolog&#237;a&#46; Hospital del Ni&#241;o"
            "etiqueta" => "<span class="elsevierStyleSup">a</span>"
            "identificador" => "aff1"
          ]
          1 => array:3 [
            "entidad" => "Servicio de Pediatr&#237;a&#46; Hospital del Ni&#241;o"
            "etiqueta" => "<span class="elsevierStyleSup">b</span>"
            "identificador" => "aff2"
          ]
          2 => array:3 [
            "entidad" => "Instituto de Investigaciones Cient&#237;ficas Avanzadas y Servicios de Alta Tecnolog&#237;a"
            "etiqueta" => "<span class="elsevierStyleSup">c</span>"
            "identificador" => "aff3"
          ]
          3 => array:3 [
            "entidad" => "Laboratorio Cl&#237;nico&#46; Hospital del Ni&#241;o&#46; Panam&#225;"
            "etiqueta" => "<span class="elsevierStyleSup">d</span>"
            "identificador" => "aff4"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor1"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Correspondencia&#58; Dra&#46; D&#46; Estripeaut&#46; Servicio de Infectolog&#237;a&#46; Hospital del Ni&#241;o&#46; Av&#46; Balboa&#44; 34&#46; Panam&#225;&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "en" => array:1 [
        "titulo" => "Seroprevalence of cytomegalovirus infection in puerperal women and its impact on their newborns"
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2005-12-31"
    "fechaAceptado" => "2006-09-30"
    "PalabrasClave" => array:2 [
      "es" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec246174"
          "palabras" => array:3 [
            0 => "Citomegalovirus"
            1 => "Seroprevalencia"
            2 => "Infecci&#243;n cong&#233;nita"
          ]
        ]
      ]
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Key words"
          "identificador" => "xpalclavsec246173"
          "palabras" => array:3 [
            0 => "Cytomegalovirus"
            1 => "Seroprevalence"
            2 => "Congenital infection"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "es" => array:1 [
        "resumen" => "<span class="elsevierStyleSectionTitle">Introducci&#243;n</span><p class="elsevierStyleSimplePara elsevierViewall">El citomegalovirus &#40;CMV&#41; es el agente etiol&#243;gico m&#225;s com&#250;n asociado a infecci&#243;n perinatal&#46; La incidencia de esta afecci&#243;n neonatal es m&#225;s elevada en pa&#237;ses con nivel socioecon&#243;mico bajo&#46; La seroprevalencia del CMV en las embarazadas paname&#241;as y la incidencia de la infecci&#243;n cong&#233;nita son desconocidas&#44; son tambi&#233;n escasos los informes al respecto publicados en Latinoam&#233;rica&#46;</p> <span class="elsevierStyleSectionTitle">Objetivo</span><p class="elsevierStyleSimplePara elsevierViewall">El objetivo de este estudio es determinar la seroprevalencia de la infecci&#243;n por CMV en pu&#233;rperas y la potencial morbilidad en los hijos de madres seropositivas&#46;</p> <span class="elsevierStyleSectionTitle">Pacientes y m&#233;todos</span><p class="elsevierStyleSimplePara elsevierViewall">Se tomaron 316 muestras de sangre a mujeres pu&#233;rperas para determinaci&#243;n de inmunoglobulina G &#40;IgG&#41; para CMV y 317 muestras de orina a sus neonatos para prueba de reacci&#243;n en cadena de la polimerasa &#40;PCR&#41; para CMV&#46; Adem&#225;s se analizaron presuntos factores de riesgo tales como paridad&#44; nivel socioecon&#243;mico y nivel educativo&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">Se encontr&#243; una seroprevalencia de CMV 84 &#37; y una incidencia de 0&#44;8 &#37; de CMV cong&#233;nito en mujeres seropositivas&#46; Se diagnosticaron 2 casos de infecci&#243;n cong&#233;nita por CMV&#44; uno de los cuales present&#243; signos cl&#237;nicos al nacimiento&#44; pero ninguno de ellos present&#243; secuelas auditivas o en el neurodesarrollo en sus primeros 11 meses de vida&#46; No se document&#243; asociaci&#243;n de serolog&#237;a positiva con la paridad&#44; nivel socioecon&#243;mico ni educaci&#243;n de la madre&#46;</p> <span class="elsevierStyleSectionTitle">Conclusi&#243;n</span><p class="elsevierStyleSimplePara elsevierViewall">Aunque ninguno de los ni&#241;os diagnosticados con infecci&#243;n cong&#233;nita por CMV en nuestro estudio present&#243; secuelas de la misma al momento de este informe&#44; consideramos que la incidencia de infecci&#243;n cong&#233;nita encontrada de 0&#44;8 &#37; debe ser tomada en cuenta para evaluar la posibilidad de incluir las pruebas diagn&#243;sticas para CMV dentro del tamizaje neonatal e implementar medidas educativas para evitar la exposici&#243;n a posibles fuentes de este virus en madres seronegativas&#46;</p>"
      ]
      "en" => array:1 [
        "resumen" => "<span class="elsevierStyleSectionTitle">Introduction</span><p class="elsevierStyleSimplePara elsevierViewall">Cytomegalovirus &#40;CMV&#41; is the most frequent etiologic agent associated with perinatal infections&#46; The incidence of this infection is higher in developing countries&#46; The seroprevalence of CMV infection among pregnant women and its impact on newborns have not been studied in Panama and there are a few publications on this health problem in Latin America&#46;</p> <span class="elsevierStyleSectionTitle">Objective</span><p class="elsevierStyleSimplePara elsevierViewall">The purpose of this study was to determine the seroprevalence of CMV infection in puerperal women and CMV-related morbidity in the neonates of seropositive mothers&#46;</p> <span class="elsevierStyleSectionTitle">Patients and methods</span><p class="elsevierStyleSimplePara elsevierViewall">A total of 316 blood samples from puerperal women and 317 urine samples from their newborns were obtained to determine CMV IgG and the polymerase chain reaction CMV test respectively&#46; Risk factors such as parity&#44; socioeconomic status and educational level were analyzed&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">The seroprevalence of CMV was 84 &#37; and the incidence of congenital CMV infection in the newborns of seropositive women was 0&#46;8&#37;&#46; Two cases of congenital CMV infection were diagnosed&#44; one of which showed clinical signs at birth&#44; but neither of the newborns showed neurological or audiological sequels in the first 11 months of life&#46; There were no correlations between positive serology and parity&#44; socioeconomic status or educational level in the mothers studied&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">Although neither of the newborns diagnosed with congenital CMV infection showed clinical signs at the time of this report&#44; we believe that the incidence of 0&#46;8&#37; found in this study should be kept in mind with a view to evaluating the possibility of including CMV diagnostic tests in neonatal screening and introducing measures to prevent seronegative mothers from becoming infected&#46;</p>"
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "Bibliograf&#237;a"
      "seccion" => array:1 [
        0 => array:1 [
          "bibliografiaReferencia" => array:15 [
            0 => array:3 [
              "identificador" => "bib1"
              "etiqueta" => "1&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Citomegalovirus"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "P&#46; S&#225;nchez"
                            1 => "J&#46; Siegel"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "LibroEditado" => array:6 [
                        "editores" => "F&#46;OskiC&#46;De AngelisR&#46;FeiginJ&#46;Warshaw"
                        "paginaInicial" => "521"
                        "paginaFinal" => "524"
                        "serieVolumen" => "Tomo I"
                        "serieTitulo" => "Oski&#58; Pediatr&#237;a&#44; principios y pr&#225;ctica"
                        "serieFecha" => "1993"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib2"
              "etiqueta" => "2&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Congenital cytomegalovirus infection in preterm and full-term newborn infants from a population with a high seroprevalence rate"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "A&#46; Yamamoto"
                            1 => "M&#46; Mussi-Pinhata"
                            2 => "P&#46; G&#243;mez"
                            3 => "L&#46; Moraes"
                            4 => "S&#46; Jorge"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Pediatr Infect Dis J&#46;"
                        "fecha" => "2001"
                        "volumen" => "20"
                        "paginaInicial" => "188"
                        "paginaFinal" => "192"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11224840"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib3"
              "etiqueta" => "3&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Maternal age and congenital cytomegalovirus infection&#58; Screening of two diverse newborn populations&#44; 1980-1990"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "K&#46; Fowler"
                            1 => "S&#46; Stagno"
                            2 => "R&#46; Pass"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Infect Dis&#46;"
                        "fecha" => "1993"
                        "volumen" => "168"
                        "paginaInicial" => "552"
                        "paginaFinal" => "556"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8394857"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib4"
              "etiqueta" => "4&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Cytomegalovirus infection"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "R&#46;F&#46; Pass"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Pediatr Rev&#46;"
                        "fecha" => "2002"
                        "volumen" => "23"
                        "paginaInicial" => "163"
                        "paginaFinal" => "170"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11986492"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib5"
              "etiqueta" => "5&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Polymerase chain reaction to detect cytomegalovirus DNA in the cerebrospinal fluid of neonates with congenital infection"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "J&#46; Troendle Atkins"
                            1 => "G&#46;J&#46; Demmler"
                            2 => "W&#46;D&#46; Williamson"
                            3 => "J&#46;M&#46; McDonald"
                            4 => "A&#46;S&#46; Istas"
                            5 => "G&#46;J&#46; Buffone"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Infect Dis&#46;"
                        "fecha" => "1994"
                        "volumen" => "169"
                        "paginaInicial" => "1334"
                        "paginaFinal" => "1337"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8195613"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib6"
              "etiqueta" => "6&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Symptomatic congenital cytomegalovirus infection in infants born to mothers with preexisting immunity to cytomegalovirus"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "S&#46; Boppana"
                            1 => "D&#46; Fowler"
                            2 => "W&#46; Britt"
                            3 => "S&#46; Stagno"
                            4 => "R&#46; Pass"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Pediatrics"
                        "fecha" => "1999"
                        "volumen" => "104"
                        "paginaInicial" => "55"
                        "paginaFinal" => "60"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10390260"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib7"
              "etiqueta" => "7&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Infectolog&#237;a pr&#225;ctica para el pediatra"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "X&#46; S&#225;ez-Llorens"
                            1 => "E&#46; Casta&#241;o"
                            2 => "M&#46; Castrej&#243;n"
                            3 => "J&#46; Nieto"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:4 [
                        "edicion" => "1&#46;&#170; ed"
                        "fecha" => "2001"
                        "editorial" => "Editora Sibauste"
                        "editorialLocalizacion" => "Panam&#225;"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib8"
              "etiqueta" => "8&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Effect of ganciclovir therapy on hearing in symptomatic congenital cytomegalovirus disease involving the central nervous system&#58; A randomized&#44; controlled trial"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "D&#46;W&#46; Kimberlin"
                            1 => "C&#46;Y&#46; Lin"
                            2 => "P&#46;J&#46; S&#225;nchez"
                            3 => "G&#46;J&#46; Demmler"
                            4 => "W&#46; Dankner"
                            5 => "M&#46; Shelton"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Pediatr&#46;"
                        "fecha" => "2003"
                        "volumen" => "143"
                        "paginaInicial" => "16"
                        "paginaFinal" => "25"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12915819"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib9"
              "etiqueta" => "9&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Screening and diagnosis of congenital citomegalovirus infection&#58; A 5 study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "G&#46; Halwachs-Baumann"
                            1 => "B&#46; Genser"
                            2 => "M&#46; Danda"
                            3 => "E&#46; Heidi"
                            4 => "H&#46; Rosegger"
                            5 => "B&#46; Folsch"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Scand J Infect Dis&#46;"
                        "fecha" => "2000"
                        "volumen" => "32"
                        "paginaInicial" => "137"
                        "paginaFinal" => "142"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10826897"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib10"
              "etiqueta" => "10&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Detection of cytomegalovirus in urine from newborns by using polimerase chain reaction DNA amplification"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "G&#46;J&#46; Demmler"
                            1 => "G&#46;J&#46; Buffone"
                            2 => "C&#46;M&#46; Schimbor"
                            3 => "R&#46;A&#46; May"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Infect Dis&#46;"
                        "fecha" => "1988"
                        "volumen" => "158"
                        "paginaInicial" => "1177"
                        "paginaFinal" => "1184"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2848897"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib11"
              "etiqueta" => "11&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Comparison of rapid methods of detection of cytomegalovirus in saliva with virus isolation in tissue culture"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "W&#46;P&#46; Warren"
                            1 => "K&#46; Balcarek"
                            2 => "R&#46; Smith"
                            3 => "R&#46;F&#46; Pass"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Clin Microbiol&#46;"
                        "fecha" => "1992"
                        "volumen" => "30"
                        "paginaInicial" => "786"
                        "paginaFinal" => "789"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1315334"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib12"
              "etiqueta" => "12&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Congenital cytomegalovirus infection&#58; Outcome and diagnosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "S&#46;A&#46; Ross"
                            1 => "S&#46;B&#46; Boppana"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1053/j.spid.2004.09.011"
                      "Revista" => array:6 [
                        "tituloSerie" => "Semin Pediatr Infect Dis&#46;"
                        "fecha" => "2005"
                        "volumen" => "16"
                        "paginaInicial" => "44"
                        "paginaFinal" => "49"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15685149"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib13"
              "etiqueta" => "13&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Progressive and fluctuating sensorineural hearing loss in children with asymptomatic congenital cytomegalovirus infection"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "K&#46;B&#46; Fowler"
                            1 => "F&#46;P&#46; McCollister"
                            2 => "A&#46;J&#46; Dahle"
                            3 => "S&#46; Boppana"
                            4 => "W&#46;J&#46; Britt"
                            5 => "R&#46;F&#46; Pass"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Pediatr&#46;"
                        "fecha" => "1997"
                        "volumen" => "130"
                        "paginaInicial" => "624"
                        "paginaFinal" => "630"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9108862"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib14"
              "etiqueta" => "14&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Detection of cytomegalovirus &#40;CMV&#41; DNA by polymerase chain reaction is associated with hearing loss in newborns with symptomatic congenital CMV infection involving the central nervous system"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "R&#46; Bradford"
                            1 => "G&#46; Cloud"
                            2 => "A&#46; Lakeman"
                            3 => "S&#46; Boppana"
                            4 => "D&#46; Kimberlin"
                            5 => "R&#46; Jacobs"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1086/426456"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Infect Dis&#46;"
                        "fecha" => "2005"
                        "volumen" => "191"
                        "paginaInicial" => "227"
                        "paginaFinal" => "233"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15609232"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib15"
              "etiqueta" => "15&#46;"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "Estad&#237;sticas vitales&#44; nacimientos vivos y defunciones fetales&#46; Contralor&#237;a General de la Rep&#250;blica&#46; Vol&#46; II&#46; Panam&#225; 2003&#46; Disponible en&#58; <a class="elsevierStyleInterRef" href="http://www.contraloria.gob.pa/">http&#58;&#47;&#47;www&#46;contraloria&#46;gob&#46;pa</a>"
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "es"
  "url" => "/16954033/0000006600000002/v2_201308271339/S1695403307703211/v2_201308271339/es/main.assets"
  "Apartado" => array:4 [
    "identificador" => "14282"
    "tipo" => "SECCION"
    "es" => array:2 [
      "titulo" => "Originales"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "es"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/16954033/0000006600000002/v2_201308271339/S1695403307703211/v2_201308271339/es/main.pdf?idApp=UINPBA00005H&text.app=https://analesdepediatria.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1695403307703211?idApp=UINPBA00005H"
]
Compartir
Información de la revista

Estadísticas

Siga este enlace para acceder al texto completo del artículo

Originales
Seroprevalencia de la infección por citomegalovirus en puérperas y su impacto neonatal
Seroprevalence of cytomegalovirus infection in puerperal women and its impact on their newborns
D. Estripeauta,
Autor para correspondencia
destripeaut@yahoo.com

Correspondencia: Dra. D. Estripeaut. Servicio de Infectología. Hospital del Niño. Av. Balboa, 34. Panamá.
, Y. Morenob, S. Ahumada Ruizc, A. Martínezc, J.D. Racined, X. Sáez-Llorensa
a Servicio de Infectología. Hospital del Niño
b Servicio de Pediatría. Hospital del Niño
c Instituto de Investigaciones Científicas Avanzadas y Servicios de Alta Tecnología
d Laboratorio Clínico. Hospital del Niño. Panamá
Leído
12914
Veces
se ha leído el artículo
3940
Total PDF
8974
Total HTML
Compartir estadísticas
 array:23 [
  "pii" => "S1695403307703211"
  "issn" => "16954033"
  "doi" => "10.1157/13098930"
  "estado" => "S300"
  "fechaPublicacion" => "2007-02-01"
  "aid" => "70321"
  "copyright" => "Asociaci&#243;n Espa&#241;ola de Pediatr&#237;a"
  "copyrightAnyo" => "2007"
  "documento" => "article"
  "crossmark" => 0
  "subdocumento" => "fla"
  "cita" => "An Pediatr &#40;Barc&#41;. 2007;66:135-9"
  "abierto" => array:3 [
    "ES" => false
    "ES2" => false
    "LATM" => false
  ]
  "gratuito" => false
  "lecturas" => array:2 [
    "total" => 7153
    "formatos" => array:3 [
      "EPUB" => 79
      "HTML" => 6449
      "PDF" => 625
    ]
  ]
  "itemSiguiente" => array:18 [
    "pii" => "S1695403307703223"
    "issn" => "16954033"
    "doi" => "10.1157/13098931"
    "estado" => "S300"
    "fechaPublicacion" => "2007-02-01"
    "aid" => "70322"
    "copyright" => "Asociaci&#243;n Espa&#241;ola de Pediatr&#237;a"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "fla"
    "cita" => "An Pediatr &#40;Barc&#41;. 2007;66:140-5"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:2 [
      "total" => 6812
      "formatos" => array:3 [
        "EPUB" => 79
        "HTML" => 5736
        "PDF" => 997
      ]
    ]
    "es" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Originales</span>"
      "titulo" => "Utilidad del CRIB para predecir la muerte hospitalaria y la hemorragia intraventricular en los prematuros de muy bajo peso y extremado bajo peso al nacer"
      "tienePdf" => "es"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "es"
        1 => "en"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "140"
          "paginaFinal" => "145"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "en" => array:1 [
          "titulo" => "Utility of the clinical risk index for babies &#40;CRIB&#41; as a predictor of hospital death and intraventricular hemorrhage in very low birth weight and extremely low birth weight neonates"
        ]
      ]
      "contieneResumen" => array:2 [
        "es" => true
        "en" => true
      ]
      "contienePdf" => array:1 [
        "es" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "R&#46; Rivas Ruiz, J&#46;M&#46;&#170; Guzm&#225;n Caba&#241;as, M&#46;&#170;J&#46; P&#225;rraga Quiles, M&#46;&#170;D&#46; Ruiz Gonz&#225;lez, M&#46;&#170;D&#46; Huertas Mu&#241;oz, R&#46; &#193;lvarez Marcos, M&#46; Zapatero Mart&#237;nez"
          "autores" => array:7 [
            0 => array:2 [
              "nombre" => "R&#46;"
              "apellidos" => "Rivas Ruiz"
            ]
            1 => array:2 [
              "nombre" => "J&#46;M&#46;&#170;"
              "apellidos" => "Guzm&#225;n Caba&#241;as"
            ]
            2 => array:2 [
              "nombre" => "M&#46;&#170;J&#46;"
              "apellidos" => "P&#225;rraga Quiles"
            ]
            3 => array:2 [
              "nombre" => "M&#46;&#170;D&#46;"
              "apellidos" => "Ruiz Gonz&#225;lez"
            ]
            4 => array:2 [
              "nombre" => "M&#46;&#170;D&#46;"
              "apellidos" => "Huertas Mu&#241;oz"
            ]
            5 => array:2 [
              "nombre" => "R&#46;"
              "apellidos" => "&#193;lvarez Marcos"
            ]
            6 => array:2 [
              "nombre" => "M&#46;"
              "apellidos" => "Zapatero Mart&#237;nez"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "es"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1695403307703223?idApp=UINPBA00005H"
    "url" => "/16954033/0000006600000002/v2_201308271339/S1695403307703223/v2_201308271339/es/main.assets"
  ]
  "itemAnterior" => array:18 [
    "pii" => "S169540330770320X"
    "issn" => "16954033"
    "doi" => "10.1157/13098929"
    "estado" => "S300"
    "fechaPublicacion" => "2007-02-01"
    "aid" => "70320"
    "copyright" => "Asociaci&#243;n Espa&#241;ola de Pediatr&#237;a"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "fla"
    "cita" => "An Pediatr &#40;Barc&#41;. 2007;66:129-34"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:2 [
      "total" => 8765
      "formatos" => array:3 [
        "EPUB" => 92
        "HTML" => 7731
        "PDF" => 942
      ]
    ]
    "es" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Originales</span>"
      "titulo" => "Tics en ni&#241;os y adolescentes&#58; an&#225;lisis retrospectivo de 78 casos"
      "tienePdf" => "es"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "es"
        1 => "en"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "129"
          "paginaFinal" => "134"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "en" => array:1 [
          "titulo" => "Tics in children and adolescents&#58; a retrospective analysis of 78 cases"
        ]
      ]
      "contieneResumen" => array:2 [
        "es" => true
        "en" => true
      ]
      "contienePdf" => array:1 [
        "es" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "A&#46; Catarina Prior, S&#46; Tavares, S&#46; Figueiroa, T&#46; Temudo"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "A&#46;"
              "apellidos" => "Catarina Prior"
            ]
            1 => array:2 [
              "nombre" => "S&#46;"
              "apellidos" => "Tavares"
            ]
            2 => array:2 [
              "nombre" => "S&#46;"
              "apellidos" => "Figueiroa"
            ]
            3 => array:2 [
              "nombre" => "T&#46;"
              "apellidos" => "Temudo"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "es"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S169540330770320X?idApp=UINPBA00005H"
    "url" => "/16954033/0000006600000002/v2_201308271339/S169540330770320X/v2_201308271339/es/main.assets"
  ]
  "es" => array:15 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Originales</span>"
    "titulo" => "Seroprevalencia de la infecci&#243;n por citomegalovirus en pu&#233;rperas y su impacto neonatal"
    "tieneTextoCompleto" => 0
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "135"
        "paginaFinal" => "139"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "D&#46; Estripeaut, Y&#46; Moreno, S&#46; Ahumada Ruiz, A&#46; Mart&#237;nez, J&#46;D&#46; Racine, X&#46; S&#225;ez-Llorens"
        "autores" => array:6 [
          0 => array:4 [
            "nombre" => "D&#46;"
            "apellidos" => "Estripeaut"
            "email" => array:1 [
              0 => "destripeaut&#64;yahoo&#46;com"
            ]
            "referencia" => array:2 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff1"
              ]
              1 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">¿</span>"
                "identificador" => "cor1"
              ]
            ]
          ]
          1 => array:3 [
            "nombre" => "Y&#46;"
            "apellidos" => "Moreno"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">b</span>"
                "identificador" => "aff2"
              ]
            ]
          ]
          2 => array:3 [
            "nombre" => "S&#46;"
            "apellidos" => "Ahumada Ruiz"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">c</span>"
                "identificador" => "aff3"
              ]
            ]
          ]
          3 => array:3 [
            "nombre" => "A&#46;"
            "apellidos" => "Mart&#237;nez"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">c</span>"
                "identificador" => "aff3"
              ]
            ]
          ]
          4 => array:3 [
            "nombre" => "J&#46;D&#46;"
            "apellidos" => "Racine"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">d</span>"
                "identificador" => "aff4"
              ]
            ]
          ]
          5 => array:3 [
            "nombre" => "X&#46;"
            "apellidos" => "S&#225;ez-Llorens"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff1"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:4 [
          0 => array:3 [
            "entidad" => "Servicio de Infectolog&#237;a&#46; Hospital del Ni&#241;o"
            "etiqueta" => "<span class="elsevierStyleSup">a</span>"
            "identificador" => "aff1"
          ]
          1 => array:3 [
            "entidad" => "Servicio de Pediatr&#237;a&#46; Hospital del Ni&#241;o"
            "etiqueta" => "<span class="elsevierStyleSup">b</span>"
            "identificador" => "aff2"
          ]
          2 => array:3 [
            "entidad" => "Instituto de Investigaciones Cient&#237;ficas Avanzadas y Servicios de Alta Tecnolog&#237;a"
            "etiqueta" => "<span class="elsevierStyleSup">c</span>"
            "identificador" => "aff3"
          ]
          3 => array:3 [
            "entidad" => "Laboratorio Cl&#237;nico&#46; Hospital del Ni&#241;o&#46; Panam&#225;"
            "etiqueta" => "<span class="elsevierStyleSup">d</span>"
            "identificador" => "aff4"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor1"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Correspondencia&#58; Dra&#46; D&#46; Estripeaut&#46; Servicio de Infectolog&#237;a&#46; Hospital del Ni&#241;o&#46; Av&#46; Balboa&#44; 34&#46; Panam&#225;&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "en" => array:1 [
        "titulo" => "Seroprevalence of cytomegalovirus infection in puerperal women and its impact on their newborns"
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2005-12-31"
    "fechaAceptado" => "2006-09-30"
    "PalabrasClave" => array:2 [
      "es" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec246174"
          "palabras" => array:3 [
            0 => "Citomegalovirus"
            1 => "Seroprevalencia"
            2 => "Infecci&#243;n cong&#233;nita"
          ]
        ]
      ]
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Key words"
          "identificador" => "xpalclavsec246173"
          "palabras" => array:3 [
            0 => "Cytomegalovirus"
            1 => "Seroprevalence"
            2 => "Congenital infection"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "es" => array:1 [
        "resumen" => "<span class="elsevierStyleSectionTitle">Introducci&#243;n</span><p class="elsevierStyleSimplePara elsevierViewall">El citomegalovirus &#40;CMV&#41; es el agente etiol&#243;gico m&#225;s com&#250;n asociado a infecci&#243;n perinatal&#46; La incidencia de esta afecci&#243;n neonatal es m&#225;s elevada en pa&#237;ses con nivel socioecon&#243;mico bajo&#46; La seroprevalencia del CMV en las embarazadas paname&#241;as y la incidencia de la infecci&#243;n cong&#233;nita son desconocidas&#44; son tambi&#233;n escasos los informes al respecto publicados en Latinoam&#233;rica&#46;</p> <span class="elsevierStyleSectionTitle">Objetivo</span><p class="elsevierStyleSimplePara elsevierViewall">El objetivo de este estudio es determinar la seroprevalencia de la infecci&#243;n por CMV en pu&#233;rperas y la potencial morbilidad en los hijos de madres seropositivas&#46;</p> <span class="elsevierStyleSectionTitle">Pacientes y m&#233;todos</span><p class="elsevierStyleSimplePara elsevierViewall">Se tomaron 316 muestras de sangre a mujeres pu&#233;rperas para determinaci&#243;n de inmunoglobulina G &#40;IgG&#41; para CMV y 317 muestras de orina a sus neonatos para prueba de reacci&#243;n en cadena de la polimerasa &#40;PCR&#41; para CMV&#46; Adem&#225;s se analizaron presuntos factores de riesgo tales como paridad&#44; nivel socioecon&#243;mico y nivel educativo&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">Se encontr&#243; una seroprevalencia de CMV 84 &#37; y una incidencia de 0&#44;8 &#37; de CMV cong&#233;nito en mujeres seropositivas&#46; Se diagnosticaron 2 casos de infecci&#243;n cong&#233;nita por CMV&#44; uno de los cuales present&#243; signos cl&#237;nicos al nacimiento&#44; pero ninguno de ellos present&#243; secuelas auditivas o en el neurodesarrollo en sus primeros 11 meses de vida&#46; No se document&#243; asociaci&#243;n de serolog&#237;a positiva con la paridad&#44; nivel socioecon&#243;mico ni educaci&#243;n de la madre&#46;</p> <span class="elsevierStyleSectionTitle">Conclusi&#243;n</span><p class="elsevierStyleSimplePara elsevierViewall">Aunque ninguno de los ni&#241;os diagnosticados con infecci&#243;n cong&#233;nita por CMV en nuestro estudio present&#243; secuelas de la misma al momento de este informe&#44; consideramos que la incidencia de infecci&#243;n cong&#233;nita encontrada de 0&#44;8 &#37; debe ser tomada en cuenta para evaluar la posibilidad de incluir las pruebas diagn&#243;sticas para CMV dentro del tamizaje neonatal e implementar medidas educativas para evitar la exposici&#243;n a posibles fuentes de este virus en madres seronegativas&#46;</p>"
      ]
      "en" => array:1 [
        "resumen" => "<span class="elsevierStyleSectionTitle">Introduction</span><p class="elsevierStyleSimplePara elsevierViewall">Cytomegalovirus &#40;CMV&#41; is the most frequent etiologic agent associated with perinatal infections&#46; The incidence of this infection is higher in developing countries&#46; The seroprevalence of CMV infection among pregnant women and its impact on newborns have not been studied in Panama and there are a few publications on this health problem in Latin America&#46;</p> <span class="elsevierStyleSectionTitle">Objective</span><p class="elsevierStyleSimplePara elsevierViewall">The purpose of this study was to determine the seroprevalence of CMV infection in puerperal women and CMV-related morbidity in the neonates of seropositive mothers&#46;</p> <span class="elsevierStyleSectionTitle">Patients and methods</span><p class="elsevierStyleSimplePara elsevierViewall">A total of 316 blood samples from puerperal women and 317 urine samples from their newborns were obtained to determine CMV IgG and the polymerase chain reaction CMV test respectively&#46; Risk factors such as parity&#44; socioeconomic status and educational level were analyzed&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">The seroprevalence of CMV was 84 &#37; and the incidence of congenital CMV infection in the newborns of seropositive women was 0&#46;8&#37;&#46; Two cases of congenital CMV infection were diagnosed&#44; one of which showed clinical signs at birth&#44; but neither of the newborns showed neurological or audiological sequels in the first 11 months of life&#46; There were no correlations between positive serology and parity&#44; socioeconomic status or educational level in the mothers studied&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">Although neither of the newborns diagnosed with congenital CMV infection showed clinical signs at the time of this report&#44; we believe that the incidence of 0&#46;8&#37; found in this study should be kept in mind with a view to evaluating the possibility of including CMV diagnostic tests in neonatal screening and introducing measures to prevent seronegative mothers from becoming infected&#46;</p>"
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "Bibliograf&#237;a"
      "seccion" => array:1 [
        0 => array:1 [
          "bibliografiaReferencia" => array:15 [
            0 => array:3 [
              "identificador" => "bib1"
              "etiqueta" => "1&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Citomegalovirus"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "P&#46; S&#225;nchez"
                            1 => "J&#46; Siegel"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "LibroEditado" => array:6 [
                        "editores" => "F&#46;OskiC&#46;De AngelisR&#46;FeiginJ&#46;Warshaw"
                        "paginaInicial" => "521"
                        "paginaFinal" => "524"
                        "serieVolumen" => "Tomo I"
                        "serieTitulo" => "Oski&#58; Pediatr&#237;a&#44; principios y pr&#225;ctica"
                        "serieFecha" => "1993"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib2"
              "etiqueta" => "2&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Congenital cytomegalovirus infection in preterm and full-term newborn infants from a population with a high seroprevalence rate"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "A&#46; Yamamoto"
                            1 => "M&#46; Mussi-Pinhata"
                            2 => "P&#46; G&#243;mez"
                            3 => "L&#46; Moraes"
                            4 => "S&#46; Jorge"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Pediatr Infect Dis J&#46;"
                        "fecha" => "2001"
                        "volumen" => "20"
                        "paginaInicial" => "188"
                        "paginaFinal" => "192"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11224840"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib3"
              "etiqueta" => "3&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Maternal age and congenital cytomegalovirus infection&#58; Screening of two diverse newborn populations&#44; 1980-1990"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "K&#46; Fowler"
                            1 => "S&#46; Stagno"
                            2 => "R&#46; Pass"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Infect Dis&#46;"
                        "fecha" => "1993"
                        "volumen" => "168"
                        "paginaInicial" => "552"
                        "paginaFinal" => "556"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8394857"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib4"
              "etiqueta" => "4&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Cytomegalovirus infection"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "R&#46;F&#46; Pass"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Pediatr Rev&#46;"
                        "fecha" => "2002"
                        "volumen" => "23"
                        "paginaInicial" => "163"
                        "paginaFinal" => "170"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11986492"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib5"
              "etiqueta" => "5&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Polymerase chain reaction to detect cytomegalovirus DNA in the cerebrospinal fluid of neonates with congenital infection"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "J&#46; Troendle Atkins"
                            1 => "G&#46;J&#46; Demmler"
                            2 => "W&#46;D&#46; Williamson"
                            3 => "J&#46;M&#46; McDonald"
                            4 => "A&#46;S&#46; Istas"
                            5 => "G&#46;J&#46; Buffone"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Infect Dis&#46;"
                        "fecha" => "1994"
                        "volumen" => "169"
                        "paginaInicial" => "1334"
                        "paginaFinal" => "1337"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8195613"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib6"
              "etiqueta" => "6&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Symptomatic congenital cytomegalovirus infection in infants born to mothers with preexisting immunity to cytomegalovirus"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "S&#46; Boppana"
                            1 => "D&#46; Fowler"
                            2 => "W&#46; Britt"
                            3 => "S&#46; Stagno"
                            4 => "R&#46; Pass"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Pediatrics"
                        "fecha" => "1999"
                        "volumen" => "104"
                        "paginaInicial" => "55"
                        "paginaFinal" => "60"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10390260"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib7"
              "etiqueta" => "7&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Infectolog&#237;a pr&#225;ctica para el pediatra"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "X&#46; S&#225;ez-Llorens"
                            1 => "E&#46; Casta&#241;o"
                            2 => "M&#46; Castrej&#243;n"
                            3 => "J&#46; Nieto"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:4 [
                        "edicion" => "1&#46;&#170; ed"
                        "fecha" => "2001"
                        "editorial" => "Editora Sibauste"
                        "editorialLocalizacion" => "Panam&#225;"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib8"
              "etiqueta" => "8&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Effect of ganciclovir therapy on hearing in symptomatic congenital cytomegalovirus disease involving the central nervous system&#58; A randomized&#44; controlled trial"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "D&#46;W&#46; Kimberlin"
                            1 => "C&#46;Y&#46; Lin"
                            2 => "P&#46;J&#46; S&#225;nchez"
                            3 => "G&#46;J&#46; Demmler"
                            4 => "W&#46; Dankner"
                            5 => "M&#46; Shelton"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Pediatr&#46;"
                        "fecha" => "2003"
                        "volumen" => "143"
                        "paginaInicial" => "16"
                        "paginaFinal" => "25"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12915819"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib9"
              "etiqueta" => "9&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Screening and diagnosis of congenital citomegalovirus infection&#58; A 5 study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "G&#46; Halwachs-Baumann"
                            1 => "B&#46; Genser"
                            2 => "M&#46; Danda"
                            3 => "E&#46; Heidi"
                            4 => "H&#46; Rosegger"
                            5 => "B&#46; Folsch"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Scand J Infect Dis&#46;"
                        "fecha" => "2000"
                        "volumen" => "32"
                        "paginaInicial" => "137"
                        "paginaFinal" => "142"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10826897"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib10"
              "etiqueta" => "10&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Detection of cytomegalovirus in urine from newborns by using polimerase chain reaction DNA amplification"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "G&#46;J&#46; Demmler"
                            1 => "G&#46;J&#46; Buffone"
                            2 => "C&#46;M&#46; Schimbor"
                            3 => "R&#46;A&#46; May"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Infect Dis&#46;"
                        "fecha" => "1988"
                        "volumen" => "158"
                        "paginaInicial" => "1177"
                        "paginaFinal" => "1184"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2848897"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib11"
              "etiqueta" => "11&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Comparison of rapid methods of detection of cytomegalovirus in saliva with virus isolation in tissue culture"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "W&#46;P&#46; Warren"
                            1 => "K&#46; Balcarek"
                            2 => "R&#46; Smith"
                            3 => "R&#46;F&#46; Pass"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Clin Microbiol&#46;"
                        "fecha" => "1992"
                        "volumen" => "30"
                        "paginaInicial" => "786"
                        "paginaFinal" => "789"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1315334"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib12"
              "etiqueta" => "12&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Congenital cytomegalovirus infection&#58; Outcome and diagnosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "S&#46;A&#46; Ross"
                            1 => "S&#46;B&#46; Boppana"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1053/j.spid.2004.09.011"
                      "Revista" => array:6 [
                        "tituloSerie" => "Semin Pediatr Infect Dis&#46;"
                        "fecha" => "2005"
                        "volumen" => "16"
                        "paginaInicial" => "44"
                        "paginaFinal" => "49"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15685149"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib13"
              "etiqueta" => "13&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Progressive and fluctuating sensorineural hearing loss in children with asymptomatic congenital cytomegalovirus infection"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "K&#46;B&#46; Fowler"
                            1 => "F&#46;P&#46; McCollister"
                            2 => "A&#46;J&#46; Dahle"
                            3 => "S&#46; Boppana"
                            4 => "W&#46;J&#46; Britt"
                            5 => "R&#46;F&#46; Pass"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Pediatr&#46;"
                        "fecha" => "1997"
                        "volumen" => "130"
                        "paginaInicial" => "624"
                        "paginaFinal" => "630"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9108862"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib14"
              "etiqueta" => "14&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Detection of cytomegalovirus &#40;CMV&#41; DNA by polymerase chain reaction is associated with hearing loss in newborns with symptomatic congenital CMV infection involving the central nervous system"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "R&#46; Bradford"
                            1 => "G&#46; Cloud"
                            2 => "A&#46; Lakeman"
                            3 => "S&#46; Boppana"
                            4 => "D&#46; Kimberlin"
                            5 => "R&#46; Jacobs"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1086/426456"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Infect Dis&#46;"
                        "fecha" => "2005"
                        "volumen" => "191"
                        "paginaInicial" => "227"
                        "paginaFinal" => "233"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15609232"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib15"
              "etiqueta" => "15&#46;"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "Estad&#237;sticas vitales&#44; nacimientos vivos y defunciones fetales&#46; Contralor&#237;a General de la Rep&#250;blica&#46; Vol&#46; II&#46; Panam&#225; 2003&#46; Disponible en&#58; <a class="elsevierStyleInterRef" href="http://www.contraloria.gob.pa/">http&#58;&#47;&#47;www&#46;contraloria&#46;gob&#46;pa</a>"
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "es"
  "url" => "/16954033/0000006600000002/v2_201308271339/S1695403307703211/v2_201308271339/es/main.assets"
  "Apartado" => array:4 [
    "identificador" => "14282"
    "tipo" => "SECCION"
    "es" => array:2 [
      "titulo" => "Originales"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "es"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/16954033/0000006600000002/v2_201308271339/S1695403307703211/v2_201308271339/es/main.pdf?idApp=UINPBA00005H&text.app=https://analesdepediatria.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1695403307703211?idApp=UINPBA00005H"
]
Información del artículo
ISSN: 16954033
Idioma original: Español
Datos actualizados diariamente
año/Mes Html Pdf Total
2024 Noviembre 6 12 18
2024 Octubre 65 65 130
2024 Septiembre 46 66 112
2024 Agosto 63 126 189
2024 Julio 46 85 131
2024 Junio 73 74 147
2024 Mayo 39 45 84
2024 Abril 57 72 129
2024 Marzo 38 54 92
2024 Febrero 44 68 112
2024 Enero 35 64 99
2023 Diciembre 40 60 100
2023 Noviembre 54 85 139
2023 Octubre 45 73 118
2023 Septiembre 39 37 76
2023 Agosto 39 43 82
2023 Julio 31 48 79
2023 Junio 39 37 76
2023 Mayo 36 31 67
2023 Abril 20 35 55
2023 Marzo 31 41 72
2023 Febrero 27 28 55
2023 Enero 25 52 77
2022 Diciembre 48 51 99
2022 Noviembre 49 64 113
2022 Octubre 48 70 118
2022 Septiembre 56 51 107
2022 Agosto 84 76 160
2022 Julio 96 63 159
2022 Junio 80 44 124
2022 Mayo 63 61 124
2022 Abril 43 72 115
2022 Marzo 35 70 105
2022 Febrero 29 87 116
2022 Enero 42 98 140
2021 Diciembre 32 94 126
2021 Noviembre 34 103 137
2021 Octubre 48 94 142
2021 Septiembre 28 88 116
2021 Agosto 23 81 104
2021 Julio 34 67 101
2021 Junio 43 70 113
2021 Mayo 28 54 82
2021 Abril 67 126 193
2021 Marzo 83 62 145
2021 Febrero 78 34 112
2021 Enero 51 39 90
2020 Diciembre 45 28 73
2020 Noviembre 33 27 60
2020 Octubre 54 22 76
2020 Septiembre 33 26 59
2020 Agosto 20 38 58
2020 Julio 37 38 75
2020 Junio 23 41 64
2020 Mayo 51 24 75
2020 Abril 30 31 61
2020 Marzo 23 16 39
2020 Febrero 31 8 39
2020 Enero 26 15 41
2019 Diciembre 56 24 80
2019 Noviembre 29 10 39
2019 Octubre 27 16 43
2019 Septiembre 32 18 50
2019 Agosto 46 18 64
2019 Julio 31 33 64
2019 Junio 48 30 78
2019 Mayo 119 45 164
2019 Abril 145 34 179
2019 Marzo 31 8 39
2019 Febrero 28 13 41
2019 Enero 19 24 43
2018 Diciembre 24 29 53
2018 Noviembre 32 27 59
2018 Octubre 56 28 84
2018 Septiembre 22 7 29
2018 Julio 2 1 3
2018 Junio 1 0 1
2018 Mayo 6 0 6
2018 Abril 10 0 10
2018 Marzo 9 0 9
2018 Febrero 12 0 12
2018 Enero 10 0 10
2017 Diciembre 7 0 7
2017 Noviembre 15 0 15
2017 Octubre 17 0 17
2017 Septiembre 14 1 15
2017 Agosto 10 0 10
2017 Julio 18 0 18
2017 Junio 21 15 36
2017 Mayo 21 13 34
2017 Abril 12 15 27
2017 Marzo 10 6 16
2017 Febrero 9 1 10
2017 Enero 6 4 10
2016 Diciembre 26 2 28
2016 Noviembre 37 6 43
2016 Octubre 53 16 69
2016 Septiembre 40 2 42
2016 Agosto 29 8 37
2016 Julio 17 8 25
2016 Mayo 3 0 3
2016 Abril 1 0 1
2016 Febrero 1 0 1
2015 Diciembre 2 0 2
2015 Octubre 1 13 14
2015 Septiembre 3 5 8
2015 Agosto 4 10 14
2015 Julio 18 0 18
2015 Junio 19 0 19
2015 Mayo 13 0 13
2015 Abril 19 0 19
2015 Marzo 16 0 16
2015 Febrero 17 0 17
2015 Enero 18 0 18
2014 Diciembre 20 1 21
2014 Noviembre 16 0 16
2014 Octubre 26 1 27
2014 Septiembre 16 3 19
2014 Agosto 27 2 29
2014 Julio 41 4 45
2014 Junio 47 2 49
2014 Mayo 46 3 49
2014 Abril 51 2 53
2014 Marzo 49 8 57
2014 Febrero 31 12 43
2014 Enero 37 7 44
2013 Diciembre 38 4 42
2013 Noviembre 45 14 59
2013 Octubre 47 7 54
2013 Septiembre 49 11 60
2013 Agosto 47 15 62
2013 Julio 36 6 42
2013 Junio 4 2 6
2013 Mayo 7 2 9
2013 Abril 7 1 8
2013 Marzo 9 3 12
2013 Febrero 31 3 34
2013 Enero 27 0 27
2012 Diciembre 16 0 16
2012 Noviembre 15 0 15
2012 Octubre 16 2 18
2012 Septiembre 5 1 6
2012 Agosto 1 0 1
2007 Febrero 4309 0 4309
Mostrar todo

Siga este enlace para acceder al texto completo del artículo

Idiomas
Anales de Pediatría
es en

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?