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        "resumen" => "<span class="elsevierStyleSectionTitle">Antecedentes</span><p class="elsevierStyleSimplePara elsevierViewall">En los &#250;ltimos a&#241;os&#44; se ha descrito que&#44; con frecuencia&#44; los ni&#241;os con enuresis nocturna presentan hipercalciuria&#46; As&#237; mismo&#44; se acaba de comunicar que los ni&#241;os con enuresis nocturna resistente a desmopresina tienen una capacidad de concentraci&#243;n renal superior a la de aquellos pacientes con enuresis sensible a ese f&#225;rmaco&#46;</p> <span class="elsevierStyleSectionTitle">Objetivos</span><p class="elsevierStyleSimplePara elsevierViewall">Estudiar la funci&#243;n renal y la eliminaci&#243;n urinaria de calcio y registrar los antecedentes familiares de enuresis y de litiasis en un grupo de ni&#241;os enur&#233;ticos respondedores y resistentes a desmopresina controlados en nuestro hospital&#46;</p> <span class="elsevierStyleSectionTitle">Material y m&#233;todos</span><p class="elsevierStyleSimplePara elsevierViewall">Cohorte de 60 pacientes&#44; 42 varones y 18 mujeres&#44; que fueron remitidos al hospital por padecer enuresis nocturna&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">Se detect&#243; hipercalciuria en 26 ni&#241;os &#40;43&#44;3 &#37;&#41; e hipocitraturia en ocho &#40;13&#44;3 &#37;&#41;&#46; La frecuencia de hipercalciuria fue superior en los pacientes resistentes con respecto a los sensibles a desmopresina&#44; sin diferencias estad&#237;sticamente significativas&#46; En 11 ni&#241;os se detectaron anomalies morfol&#243;gicas ecogr&#225;ficas renales&#46; No se comprobaron diferencias en el manejo renal del agua al distribuir a los pacientes seg&#250;n el grado de sensibilidad a la desmopresina&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">En nuestra serie se demuestra la elevada frecuencia de hipercalciuria en ni&#241;os con enuresis nocturna&#46; No observamos diferencias en la osmolalidad urinaria maxima entre los ni&#241;os sensibles y los resistentes a la desmopresina&#46;</p>"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Background</span><p class="elsevierStyleSimplePara elsevierViewall">In the last few years&#44; there have been reports that children with nocturnal enuresis frequently have hypercalciuria&#46;Likewise&#44; children with desmopressin-resistant enuresis have recently been reported to have a higher renal concentration capacity than patients with desmopressinsensitive enuresis&#46;</p> <span class="elsevierStyleSectionTitle">Objectives</span><p class="elsevierStyleSimplePara elsevierViewall">To study renal function and urinary calcium excretion and to register familial history of enuresis and urolithiasis in a group of children with enuresis&#44; whether responders or nonresponders to desmopressin&#44; followed-up in our hospital&#46;</p> <span class="elsevierStyleSectionTitle">Material and methods</span><p class="elsevierStyleSimplePara elsevierViewall">A cohort of 60 patients &#40;42 boys and 18 girls&#41; who were referred to the hospital because of nocturnal enuresis&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">Hypercalciuria was detected in 26 children &#40;43&#46;3 &#37;&#41; and hypocitraturia in eight &#40;13&#46;3 &#37;&#41;&#46; The frequency of hyper-calciuria was higher in desmopressin-resistant patients than in desmopressin-sensitive patients&#44; but this difference was not statistically significant&#46; Sonographic renal morphological anomalies were detected in 11 children &#40;18&#46;3 &#37;&#41;&#46; No differences in renal handling of water were detected when the patients were distributed according to the grade of sensitivity to desmopressin&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">In our cohort we found a high frequency of hypercalciuria in children with nocturnal enuresis&#46; No differences were observed in maximal urinary osmolality among desmopressin-resistant and desmopressin-sensitive children&#46;</p>"
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Originales
Estudio de la morfología y la función renal en niños diagnosticados de enuresis nocturna. Su relación con la sensibilidad o la resistencia a la desmopresina
Study of renal morphology and function in children with nocturnal enuresis. Relationship with sensitivity or resistance to desmopressin
C.L. Marrero Pérez, V. García Nieto
Autor para correspondencia
vgarcia@comtf.es

Correspondencia: Dr. V. García Nieto. Unidad de Nefrología Pediátrica. Hospital Universitario Nuestra Señora de Candelaria. Ctra. del Rosario, s/n. 38010 Santa Cruz de Tenerife. España.
, M.I. Luis Yanes
Unidad de Nefrología Pediátrica. Hospital Universitario Nuestra Señora de Candelaria. Santa Cruz de Tenerife. España
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        "resumen" => "<span class="elsevierStyleSectionTitle">Antecedentes</span><p class="elsevierStyleSimplePara elsevierViewall">En los &#250;ltimos a&#241;os&#44; se ha descrito que&#44; con frecuencia&#44; los ni&#241;os con enuresis nocturna presentan hipercalciuria&#46; As&#237; mismo&#44; se acaba de comunicar que los ni&#241;os con enuresis nocturna resistente a desmopresina tienen una capacidad de concentraci&#243;n renal superior a la de aquellos pacientes con enuresis sensible a ese f&#225;rmaco&#46;</p> <span class="elsevierStyleSectionTitle">Objetivos</span><p class="elsevierStyleSimplePara elsevierViewall">Estudiar la funci&#243;n renal y la eliminaci&#243;n urinaria de calcio y registrar los antecedentes familiares de enuresis y de litiasis en un grupo de ni&#241;os enur&#233;ticos respondedores y resistentes a desmopresina controlados en nuestro hospital&#46;</p> <span class="elsevierStyleSectionTitle">Material y m&#233;todos</span><p class="elsevierStyleSimplePara elsevierViewall">Cohorte de 60 pacientes&#44; 42 varones y 18 mujeres&#44; que fueron remitidos al hospital por padecer enuresis nocturna&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">Se detect&#243; hipercalciuria en 26 ni&#241;os &#40;43&#44;3 &#37;&#41; e hipocitraturia en ocho &#40;13&#44;3 &#37;&#41;&#46; La frecuencia de hipercalciuria fue superior en los pacientes resistentes con respecto a los sensibles a desmopresina&#44; sin diferencias estad&#237;sticamente significativas&#46; En 11 ni&#241;os se detectaron anomalies morfol&#243;gicas ecogr&#225;ficas renales&#46; No se comprobaron diferencias en el manejo renal del agua al distribuir a los pacientes seg&#250;n el grado de sensibilidad a la desmopresina&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">En nuestra serie se demuestra la elevada frecuencia de hipercalciuria en ni&#241;os con enuresis nocturna&#46; No observamos diferencias en la osmolalidad urinaria maxima entre los ni&#241;os sensibles y los resistentes a la desmopresina&#46;</p>"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Background</span><p class="elsevierStyleSimplePara elsevierViewall">In the last few years&#44; there have been reports that children with nocturnal enuresis frequently have hypercalciuria&#46;Likewise&#44; children with desmopressin-resistant enuresis have recently been reported to have a higher renal concentration capacity than patients with desmopressinsensitive enuresis&#46;</p> <span class="elsevierStyleSectionTitle">Objectives</span><p class="elsevierStyleSimplePara elsevierViewall">To study renal function and urinary calcium excretion and to register familial history of enuresis and urolithiasis in a group of children with enuresis&#44; whether responders or nonresponders to desmopressin&#44; followed-up in our hospital&#46;</p> <span class="elsevierStyleSectionTitle">Material and methods</span><p class="elsevierStyleSimplePara elsevierViewall">A cohort of 60 patients &#40;42 boys and 18 girls&#41; who were referred to the hospital because of nocturnal enuresis&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">Hypercalciuria was detected in 26 children &#40;43&#46;3 &#37;&#41; and hypocitraturia in eight &#40;13&#46;3 &#37;&#41;&#46; The frequency of hyper-calciuria was higher in desmopressin-resistant patients than in desmopressin-sensitive patients&#44; but this difference was not statistically significant&#46; Sonographic renal morphological anomalies were detected in 11 children &#40;18&#46;3 &#37;&#41;&#46; No differences in renal handling of water were detected when the patients were distributed according to the grade of sensitivity to desmopressin&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">In our cohort we found a high frequency of hypercalciuria in children with nocturnal enuresis&#46; No differences were observed in maximal urinary osmolality among desmopressin-resistant and desmopressin-sensitive children&#46;</p>"
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ISSN: 16954033
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