Concentraciones de calcio y de marcadores de remodelamiento óseo en sangre de cordón umbilical y en orina del recién nacido en el parto
Concentrations of calcium and bone remodeling biomarkers in umbilical cord blood and urine of newborn infants during delivery
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Torrico Román, G. Trinidad Ramos, M.<span class="elsevierStyleSup">a</span>C. de Cáceres Morillo, S. Lozano Sánchez, J. López-Ríos Velasco" "autores" => array:5 [ 0 => array:2 [ "nombre" => "P." "apellidos" => "Torrico Román" ] 1 => array:2 [ "nombre" => "G." "apellidos" => "Trinidad Ramos" ] 2 => array:2 [ "nombre" => "M.<span class="elsevierStyleSup">a</span>C." "apellidos" => "de Cáceres Morillo" ] 3 => array:2 [ "nombre" => "S." "apellidos" => "Lozano Sánchez" ] 4 => array:2 [ "nombre" => "J." "apellidos" => "López-Ríos Velasco" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1695403301775273?idApp=UINPBA00005H" "url" => "/16954033/0000005400000003/v1_201307051543/S1695403301775273/v1_201307051543/es/main.assets" ] "es" => array:14 [ "idiomaDefecto" => true "titulo" => "Concentraciones de calcio y de marcadores de remodelamiento óseo en sangre de cordón umbilical y en orina del recién nacido en el parto" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "290" "paginaFinal" => "296" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "A. de Toro Salas, J.L. Dueñas Díez, E. de Jaime Revuelta" "autores" => array:3 [ 0 => array:4 [ "nombre" => "A." "apellidos" => "de Toro Salas" "email" => array:1 [ 0 => "med009753@nacom.es" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "J.L." "apellidos" => "Dueñas Díez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 2 => array:3 [ "nombre" => "E." "apellidos" => "de Jaime Revuelta" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Servicios de Ginecología. Hospital Universitario Virgen de la Macarena. Sevilla" "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Servicios de Pediatría. Hospital Universitario Virgen de la Macarena. Sevilla" "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "*" "correspondencia" => "Correspondencia: Ximénez de Enciso, 22, 1.° B. 41004 Sevilla" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Concentrations of calcium and bone remodeling biomarkers in umbilical cord blood and urine of newborn infants during delivery" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2000-05-31" "fechaAceptado" => "2000-09-30" "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec186595" "palabras" => array:5 [ 0 => "Osteocalcina" 1 => "Piridinolinas" 2 => "Gestación" 3 => "Parto" 4 => "Cordón umbilical" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec186596" "palabras" => array:5 [ 0 => "Osteocalcin" 1 => "Pyridinolines" 2 => "Pregnancy" 3 => "Delivery" 4 => "Umbilical cord" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Evaluar las concentraciones de calcio, fósforo, paratormona (PTH), osteocalcina y fosfatasa alcalina en sangre de cordón umbilical y de las piridinolinas urinarias junto con el cálculo del cociente piridinolinas/creatinina, con el fin de estimar, indirectamente, el proceso de remodelamiento óseo fetal, comparando los valores de estos marcadores con los obtenidos de la madre durante el parto y el tercer trimestre de gestación</p> <span class="elsevierStyleSectionTitle">Pacientes y métodos</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Se estudiaron los valores séricos de calcio, fósforo,PTH, osteocalcina, fosfatasa alcalina y de piridinolinas en orina, y se procedió al cálculo del cociente piridinolinas/creatinina en 38 gestantes normales durante los últimos 2 meses de gestación y durante el parto. Se obtuvieron muestras de sangre de la vena umbilical durante el período del alumbramiento, y de orina de los mismos recién nacidos en las primeras 24 h puerperales para determinar estos parámetros</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">El valor del calcio en la sangre de cordón fue superior al obtenido en sangre materna durante el parto. Las concentraciones de PTH en sangre de cordón fueron muy inferiores a las obtenidas en sangre materna, las de fosfatasa alcalina fueron similares y las de osteocalcina, superiores.El valor medio de las piridinolinas en orina del recién nacido fue muy superior a los obtenidos en la madre durante el tercer trimestre del embarazo y en el parto</p> <span class="elsevierStyleSectionTitle">Conclusión</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">El recién nacido es hipercalcémico respecto a la madreen el momento del parto y presenta un estado de hipoparatiroidismo relativo. En general, los marcadores de remodelamiento óseo presentan unos valores más elevados en el recién nacido que en la madre, mostrando una alta tasa de remodelamiento óseo</p>" ] "en" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">To evaluate calcium, phosphorus, parathormone (PTH),osteocalcin, and alkaline phosphatase concentrations in cord blood, pyridinoline concentrations in urine, and the pyridinoline/creatinine ratio in order to indirectly assess late bone remodeling in the newborn by comparing concentrations of these substances with those in the mother during the third trimester and delivery</p> <span class="elsevierStyleSectionTitle">Patients and methods</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Calcium, phosphorus, PTH, osteocalcin, and alkaline phosphatase levels in cord blood, pyridinolines in urine and the pyridinoline/creatinine ratio were evaluated in 38 healthy pregnant women during the last two months of pregnancy and during delivery. To determine concentrations of these substances, samples from vein umbilical cord blood were obtained immediately after birth and urine samples were obtained from the neonates within 24 hours of delivery</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">The mean calcium concentration in cord blood was higher than maternal values during delivery. Concentrations of PTH in cord blood were much lower than those in maternal blood during pregnancy, alkaline phosphatase levels were similar, and osteocalcin levels were higher. Mean urine pyridinoline concentrations in the neonates were much higher than those in the mother during the third trimester and delivery</p> <span class="elsevierStyleSectionTitle">Conclusion</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">During delivery newborn infants are hypercalcemic compared with their mothers, presenting a state of relative hypoparathyroidism. 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| año/Mes | Html | Total | |
|---|---|---|---|
| 2024 Noviembre | 7 | 16 | 23 |
| 2024 Octubre | 29 | 57 | 86 |
| 2024 Septiembre | 32 | 54 | 86 |
| 2024 Agosto | 45 | 87 | 132 |
| 2024 Julio | 38 | 51 | 89 |
| 2024 Junio | 41 | 40 | 81 |
| 2024 Mayo | 31 | 38 | 69 |
| 2024 Abril | 25 | 37 | 62 |
| 2024 Marzo | 27 | 43 | 70 |
| 2024 Febrero | 33 | 48 | 81 |
| 2024 Enero | 25 | 44 | 69 |
| 2023 Diciembre | 27 | 27 | 54 |
| 2023 Noviembre | 19 | 30 | 49 |
| 2023 Octubre | 32 | 34 | 66 |
| 2023 Septiembre | 16 | 31 | 47 |
| 2023 Agosto | 24 | 22 | 46 |
| 2023 Julio | 28 | 35 | 63 |
| 2023 Junio | 21 | 31 | 52 |
| 2023 Mayo | 30 | 30 | 60 |
| 2023 Abril | 19 | 33 | 52 |
| 2023 Marzo | 24 | 38 | 62 |
| 2023 Febrero | 14 | 25 | 39 |
| 2023 Enero | 10 | 36 | 46 |
| 2022 Diciembre | 25 | 43 | 68 |
| 2022 Noviembre | 37 | 69 | 106 |
| 2022 Octubre | 22 | 42 | 64 |
| 2022 Septiembre | 26 | 33 | 59 |
| 2022 Agosto | 29 | 50 | 79 |
| 2022 Julio | 26 | 49 | 75 |
| 2022 Junio | 24 | 41 | 65 |
| 2022 Mayo | 29 | 48 | 77 |
| 2022 Abril | 36 | 56 | 92 |
| 2022 Marzo | 22 | 50 | 72 |
| 2022 Febrero | 14 | 32 | 46 |
| 2022 Enero | 28 | 40 | 68 |
| 2021 Diciembre | 19 | 49 | 68 |
| 2021 Noviembre | 21 | 39 | 60 |
| 2021 Octubre | 28 | 45 | 73 |
| 2021 Septiembre | 23 | 38 | 61 |
| 2021 Agosto | 17 | 29 | 46 |
| 2021 Julio | 14 | 42 | 56 |
| 2021 Junio | 17 | 29 | 46 |
| 2021 Mayo | 21 | 26 | 47 |
| 2021 Abril | 23 | 43 | 66 |
| 2021 Marzo | 33 | 23 | 56 |
| 2021 Febrero | 38 | 14 | 52 |
| 2021 Enero | 27 | 17 | 44 |
| 2020 Diciembre | 35 | 12 | 47 |
| 2020 Noviembre | 27 | 11 | 38 |
| 2020 Octubre | 16 | 7 | 23 |
| 2020 Septiembre | 14 | 10 | 24 |
| 2020 Agosto | 9 | 11 | 20 |
| 2020 Julio | 29 | 9 | 38 |
| 2020 Junio | 18 | 11 | 29 |
| 2020 Mayo | 28 | 15 | 43 |
| 2020 Abril | 18 | 9 | 27 |
| 2020 Marzo | 37 | 12 | 49 |
| 2020 Febrero | 27 | 17 | 44 |
| 2020 Enero | 33 | 25 | 58 |
| 2019 Diciembre | 40 | 29 | 69 |
| 2019 Noviembre | 28 | 12 | 40 |
| 2019 Octubre | 20 | 13 | 33 |
| 2019 Septiembre | 26 | 22 | 48 |
| 2019 Agosto | 16 | 17 | 33 |
| 2019 Julio | 25 | 37 | 62 |
| 2019 Junio | 31 | 40 | 71 |
| 2019 Mayo | 31 | 52 | 83 |
| 2019 Abril | 44 | 42 | 86 |
| 2019 Marzo | 18 | 18 | 36 |
| 2019 Febrero | 22 | 13 | 35 |
| 2019 Enero | 23 | 16 | 39 |
| 2018 Diciembre | 13 | 11 | 24 |
| 2018 Noviembre | 39 | 11 | 50 |
| 2018 Octubre | 60 | 17 | 77 |
| 2018 Septiembre | 14 | 6 | 20 |
| 2018 Agosto | 1 | 0 | 1 |
| 2018 Julio | 2 | 0 | 2 |
| 2018 Abril | 12 | 0 | 12 |
| 2018 Marzo | 11 | 0 | 11 |
| 2018 Febrero | 2 | 0 | 2 |
| 2018 Enero | 6 | 0 | 6 |
| 2017 Diciembre | 8 | 0 | 8 |
| 2017 Noviembre | 6 | 0 | 6 |
| 2017 Octubre | 9 | 0 | 9 |
| 2017 Septiembre | 12 | 0 | 12 |
| 2017 Agosto | 12 | 0 | 12 |
| 2017 Julio | 13 | 1 | 14 |
| 2017 Junio | 17 | 7 | 24 |
| 2017 Mayo | 14 | 4 | 18 |
| 2017 Abril | 12 | 12 | 24 |
| 2017 Marzo | 9 | 4 | 13 |
| 2017 Febrero | 10 | 5 | 15 |
| 2017 Enero | 6 | 4 | 10 |
| 2016 Diciembre | 27 | 11 | 38 |
| 2016 Noviembre | 33 | 6 | 39 |
| 2016 Octubre | 36 | 15 | 51 |
| 2016 Septiembre | 25 | 9 | 34 |
| 2016 Agosto | 25 | 6 | 31 |
| 2016 Julio | 17 | 12 | 29 |
| 2016 Mayo | 0 | 7 | 7 |
| 2016 Marzo | 5 | 0 | 5 |
| 2016 Febrero | 3 | 0 | 3 |
| 2016 Enero | 1 | 0 | 1 |
| 2015 Diciembre | 2 | 0 | 2 |
| 2015 Octubre | 2 | 0 | 2 |
| 2015 Septiembre | 3 | 0 | 3 |
| 2015 Agosto | 4 | 0 | 4 |
| 2015 Julio | 8 | 7 | 15 |
| 2015 Junio | 8 | 0 | 8 |
| 2015 Mayo | 13 | 4 | 17 |
| 2015 Abril | 15 | 3 | 18 |
| 2015 Marzo | 10 | 0 | 10 |
| 2015 Febrero | 10 | 9 | 19 |
| 2015 Enero | 11 | 1 | 12 |
| 2014 Diciembre | 15 | 2 | 17 |
| 2014 Noviembre | 17 | 1 | 18 |
| 2014 Octubre | 17 | 1 | 18 |
| 2014 Septiembre | 16 | 2 | 18 |
| 2014 Agosto | 31 | 2 | 33 |
| 2014 Julio | 37 | 1 | 38 |
| 2014 Junio | 56 | 4 | 60 |
| 2014 Mayo | 39 | 7 | 46 |
| 2014 Abril | 43 | 2 | 45 |
| 2014 Marzo | 50 | 8 | 58 |
| 2014 Febrero | 43 | 6 | 49 |
| 2014 Enero | 38 | 8 | 46 |
| 2013 Diciembre | 48 | 7 | 55 |
| 2013 Noviembre | 38 | 12 | 50 |
| 2013 Octubre | 32 | 16 | 48 |
| 2013 Septiembre | 24 | 7 | 31 |
| 2013 Agosto | 45 | 10 | 55 |
| 2013 Julio | 32 | 7 | 39 |
| 2013 Junio | 3 | 6 | 9 |
| 2013 Mayo | 3 | 3 | 6 |
| 2013 Abril | 5 | 0 | 5 |
| 2013 Marzo | 5 | 2 | 7 |
| 2013 Febrero | 14 | 3 | 17 |
| 2013 Enero | 11 | 1 | 12 |
| 2012 Diciembre | 3 | 1 | 4 |
| 2012 Noviembre | 2 | 3 | 5 |
| 2012 Octubre | 2 | 1 | 3 |
| 2012 Septiembre | 1 | 0 | 1 |
| 2012 Agosto | 1 | 1 | 2 |
| 2001 Marzo | 1422 | 0 | 1422 |
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