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Genética de las cardiopatías congénitas
Congenital heart malformations
M. Moreno García
Autor para correspondencia
mmoreno@tdi.es

Correspondencia: Servicio de Genética. Hospital 12 de Octubre.Edificio Materno-Infantil 2.a planta B. Carretera de Andalucía, km 5,4. 28041 Madrid.
, M.J. Gómez Rodríguez, E. Barreiro Miranda
Servicio de Genética. Hospital 12 de Octubre. Madrid
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        "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Las cardiopat&#237;as son las malformaciones cong&#233;nitas m&#225;s frecuentes&#44; afectan al 0&#44;5-1&#37; de los reci&#233;n nacidos vivos&#46; Una parte son de origen gen&#233;tico&#46; Se han visto patrones de herencia autos&#243;mica dominante&#44; autos&#243;mica recesiva&#44; herencia ligada al cromosoma X y herencia mitocondrial&#46; Pueden ser tambi&#233;n causadas por anomal&#237;as cromos&#243;micas&#46; Se han identificado varios genes responsables de cardiopat&#237;as cong&#233;nitas&#46; En este art&#237;culo revisamos el estado actual de conocimiento de las cardiopat&#237;as cong&#233;nitas de origen gen&#233;tico&#46;</p>"
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        "resumen" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Congenital heart malformations are the most common of all birth defects&#44; affecting 0&#46;5-1&#37; of all live births&#46; Some of these malformations are due to genetic anomalies&#46; Patterns of autosomal dominant&#44; autosomal recessive and X-linked inheritance have been described&#46; Mitochondrial inheritance and chromosomal anomalies can also be responsible for congenital heart malformations&#46; Several genes for congenital heart defects have been identified&#46; We review current knowledge on the genetic etiology of congenital heart disease&#46;</p>"
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ISSN: 16954033
Idioma original: Español
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