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        "resumen" => "<span class="elsevierStyleSectionTitle">Fundamento</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">El papel que desempe&#241;a la leche materna&#44; en especial los &#225;cidos grasos poliinsaturados de cadena larga n-3&#44; en el desarrollo intelectual del ni&#241;o sano a t&#233;rmino sigue suscitando pol&#233;mica en la actualidad</p> <span class="elsevierStyleSectionTitle">Pacientes y m&#233;todos</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Se realiz&#243; un estudio prospectivo y ciego con 39 ni&#241;os sanos a t&#233;rmino pertenecientes a familias de nivel sociocultural homog&#233;neo&#46; Se dividieron de forma no aleatorizada en dos grupos alimentados con leche materna o leche infantil convencional&#46; A los 7 y 60 d&#237;as se midieron las concentraciones de &#225;cidos grasos poliinsaturados de cadena larga en fosfol&#237;pidos de membrana de los hemat&#237;es en 12 ni&#241;os con lactancia natural y 6 ni&#241;os con lactancia artificial&#46; Al final del segundo a&#241;o se evalu&#243; el desarrollo intelectual del total de ni&#241;os mediante el test de Bayley</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">La concentraci&#243;n de &#225;cido docosahexaenoico en los fosfol&#237;pidos fosfatidilcolina y fosfatidiletanolamina de la membrana del hemat&#237;e fue significativamente inferior en el grupo de ni&#241;os con lactancia artificial&#46; No se encontraron diferencias significativas en el desarrollo intelectual entre los grupos&#46; Se hall&#243; una asociaci&#243;n significativa entre el &#237;ndice de desarrollo mental y las variables per&#237;metro cef&#225;lico del ni&#241;o y grado de educaci&#243;n materno</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">El tipo de lactancia recibida y&#44; como consecuencia&#44; las diferencias en el perfil de &#225;cidos grasos poliinsaturados de cadena larga en la membrana del hemat&#237;e&#44; no se han relacionado con el desarrollo intelectual alcanzado al segundo a&#241;o de vida&#46; Sin embargo&#44; el per&#237;metro cef&#225;lico del ni&#241;o y la educaci&#243;n y trabajo materno s&#237; han resultado relevantes</p>"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Background</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">The role of breast milk with regard to W3 long-chain polyunsaturated fatty acids and infant intellectual development remains controversial</p> <span class="elsevierStyleSectionTitle">Patients and methods</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Thirty-nine children born at term and from homogeneous sociocultural status were enrolled in a blind-prospective trial&#46; Children were divided in two non-randomized groups&#58; a breast-fed group and a standard formula-fed group&#46; Red blood cell phospholipid fatty acids were analyzed at 7 and 60 days of life&#46; Cognitive development was evaluated at the end of the second year of life through Bailey&#39;s test</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Concentrations of phosphatidylethanolamine and phosphatidylcholine docosahexaenoic acid were significantly lower in the formula-fed group&#46; No statistically significant differences between groups were found in cognitive function&#46; Brain development index was significantly correlated with infant head circumference and educational status of the mother</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Maternal nutrition provides higher red blood cell do-cosahexaenoic acid&#44; but is not related to a higher developmental quotient at the age of 2 years&#46; However&#44; infant head circumference and maternal educational status were correlated with developmental cognition</p>"
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Desarrollo intelectual en el segundo año de vida en niños sanos lactados de forma natural frente a los lactados artificialmente
Intellectual development in the second year of life in healthy breast-fed children vs. formula-fed children
M. Santiago Burruchagaa, J.I. Ruiz Sanzb, J.I. Pijoan Zubizarretac, J. Benito Fernándezb, P. Sanjurjo Crespob,*
a Equipo de Atención Primaria Miraballes-Ugao. Hospital de Cruces. Baracaldo. Vizcaya
b Unidad de Metabolismo Infantil. Departamento de Pediatría Hospital de Cruces. Baracaldo. Vizcaya
c Unidad de Epidemiología Clínica. Hospital de Cruces. Baracaldo. Vizcaya
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      "en" => array:1 [
        "titulo" => "Intellectual development in the second year of life in healthy breast-fed children vs&#46; formula-fed children"
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          "palabras" => array:4 [
            0 => "Lactancia materna"
            1 => "&#193;cido docosahexaenoico"
            2 => "Lactancia artificial"
            3 => "Desarrollo intelectual temprano"
          ]
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      ]
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            0 => "Breast-fed infants"
            1 => "Docosahexaenoic acid"
            2 => "Formula-fed infants"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Fundamento</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">El papel que desempe&#241;a la leche materna&#44; en especial los &#225;cidos grasos poliinsaturados de cadena larga n-3&#44; en el desarrollo intelectual del ni&#241;o sano a t&#233;rmino sigue suscitando pol&#233;mica en la actualidad</p> <span class="elsevierStyleSectionTitle">Pacientes y m&#233;todos</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Se realiz&#243; un estudio prospectivo y ciego con 39 ni&#241;os sanos a t&#233;rmino pertenecientes a familias de nivel sociocultural homog&#233;neo&#46; Se dividieron de forma no aleatorizada en dos grupos alimentados con leche materna o leche infantil convencional&#46; A los 7 y 60 d&#237;as se midieron las concentraciones de &#225;cidos grasos poliinsaturados de cadena larga en fosfol&#237;pidos de membrana de los hemat&#237;es en 12 ni&#241;os con lactancia natural y 6 ni&#241;os con lactancia artificial&#46; Al final del segundo a&#241;o se evalu&#243; el desarrollo intelectual del total de ni&#241;os mediante el test de Bayley</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">La concentraci&#243;n de &#225;cido docosahexaenoico en los fosfol&#237;pidos fosfatidilcolina y fosfatidiletanolamina de la membrana del hemat&#237;e fue significativamente inferior en el grupo de ni&#241;os con lactancia artificial&#46; No se encontraron diferencias significativas en el desarrollo intelectual entre los grupos&#46; Se hall&#243; una asociaci&#243;n significativa entre el &#237;ndice de desarrollo mental y las variables per&#237;metro cef&#225;lico del ni&#241;o y grado de educaci&#243;n materno</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">El tipo de lactancia recibida y&#44; como consecuencia&#44; las diferencias en el perfil de &#225;cidos grasos poliinsaturados de cadena larga en la membrana del hemat&#237;e&#44; no se han relacionado con el desarrollo intelectual alcanzado al segundo a&#241;o de vida&#46; Sin embargo&#44; el per&#237;metro cef&#225;lico del ni&#241;o y la educaci&#243;n y trabajo materno s&#237; han resultado relevantes</p>"
      ]
      "en" => array:1 [
        "resumen" => "<span class="elsevierStyleSectionTitle">Background</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">The role of breast milk with regard to W3 long-chain polyunsaturated fatty acids and infant intellectual development remains controversial</p> <span class="elsevierStyleSectionTitle">Patients and methods</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Thirty-nine children born at term and from homogeneous sociocultural status were enrolled in a blind-prospective trial&#46; Children were divided in two non-randomized groups&#58; a breast-fed group and a standard formula-fed group&#46; Red blood cell phospholipid fatty acids were analyzed at 7 and 60 days of life&#46; Cognitive development was evaluated at the end of the second year of life through Bailey&#39;s test</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Concentrations of phosphatidylethanolamine and phosphatidylcholine docosahexaenoic acid were significantly lower in the formula-fed group&#46; No statistically significant differences between groups were found in cognitive function&#46; Brain development index was significantly correlated with infant head circumference and educational status of the mother</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Maternal nutrition provides higher red blood cell do-cosahexaenoic acid&#44; but is not related to a higher developmental quotient at the age of 2 years&#46; However&#44; infant head circumference and maternal educational status were correlated with developmental cognition</p>"
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Información del artículo
ISSN: 16954033
Idioma original: Español
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