Uso de antibióticos en niños hospitalizados por infección respiratoria aguda
Antibiotic Prescribing Patterns In Pediatric Inpatients With Acute Respiratory Tract Infection
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"apellidos" => "Escorihuela Esteban" "email" => array:1 [ 0 => "rescorihuela@fjd.es" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "J.A." "apellidos" => "Fernández Merchán" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 2 => array:3 [ "nombre" => "A." "apellidos" => "Millán Jiménez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 3 => array:3 [ "nombre" => "T." "apellidos" => "Carrión Mera" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 4 => array:3 [ "nombre" => "G." "apellidos" => "del Río Camacho" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 5 => array:3 [ "nombre" => "I." "apellidos" => "Gadea Gironés" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0010" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Servicio de Pediatría. Fundación Jiménez Díaz. Universidad Autónoma. Madrid." "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Departamento de Microbiología Fundación Jiménez Díaz. Universidad Autónoma. Madrid." "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "*" "correspondencia" => "Dr. R. Escorihuela. Servicio Pediatría. FJD. Avda. Reyes Católicos, 2. 28040 Madrid." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Antibiotic Prescribing Patterns In Pediatric Inpatients With Acute Respiratory Tract Infection" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "1999-02-28" "fechaAceptado" => "1999-10-31" "PalabrasClave" => array:1 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec186234" "palabras" => array:7 [ 0 => "Infección respiratoria aguda" 1 => "Neumonía" 2 => "Bronquiolitis" 3 => "Virus respiratorio sincitial" 4 => "Adenovirus" 5 => "Tratamiento antibiótico" 6 => "Niños" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Antecedentes</span><p id="spar1005" class="elsevierStyleSimplePara elsevierViewall">Los niños con infección respiratoria aguda constituyen un grupo permanente de estudio para evitar el tratamiento innecesario con antibióticos.</p> <span class="elsevierStyleSectionTitle">Objetivo</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Presentar los datos epidemiológicos y estudiar el efecto que tienen los datos clínicos, analíticos, radiológicos y microbiológicos en la decisión de tratar con antibióticos a niños hospitalizados por infección respiratoria aguda, buscando criterios que justifiquen su uso</p> <span class="elsevierStyleSectionTitle">Pacientes y métodos</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Se revisan las historias clínicas de 147 niños ingresados consecutivamente por catarro de vías altas, bronquitis, bronquiolitis y neumonía, durante un año (mayo 1996-abril 1997). Los pacientes se dividieron en 2 grupos: pacientes no tratados con antibióticos (n = 92), y pacientes tratados (n = 55) y se compararon estadísticamente los datos mediante un programa R-Sigma</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">En el conjunto de la serie, la edad media fue de 2,5 años con predominio de varones 85 (58%); habían consultado previamente en urgencias 105 pacientes (72%) y estaban recibiendo antibióticos 45 pacientes (30%). Se diagnosticó catarro de vías altas en 81 pacientes (54%), bronquitis en 28 (18%), bronquiolitis en 23 (15%) y neumonía en 15 (10%). Hubo 97 pacientes (66%) con infección viral demostrada y 2 (1%) bacteriana. El virus respiratorio sincitial se aisló en 41 pacientes (28%) y el adenovirus en 30 (20%). Entre los pacientes no tratados resultaron estadísticamente significativos la mayor duración de los síntomas antes del ingreso, la linfocitosis, el diagnóstico de bronquiolitis y la radiografía de tórax normal. Entre los pacientes tratados fueron estadísticamente significativas fiebre, leucocitosis, neutrofilia y el diagnóstico de neumonía, siendo así mismo más larga la estancia hospitalaria</p> <span class="elsevierStyleSectionTitle">Conclusión</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">En nuestro medio, es difícil indicar un tratamiento antibiótico basándose en criterios bacteriológicos; los criterios clínicos, radiológicos y analíticos pueden ayudar en la toma de decisiones</p>" ] "en" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Background</span><p id="spar1025" class="elsevierStyleSimplePara elsevierViewall">Children with acute respiratory tract infection (ARTI) represent an important target group for efforts aimed at reducing unnecessary antibiotic use.</p> <span class="elsevierStyleSectionTitle">Objective</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">To present the epidemiological data and evaluate the effect of clinical, laboratory, radiological and microbiological data on the decision to prescribe antibiotics to pediatric patients with ARTI as well as to seek criteria that would justify antibiotic use</p> <span class="elsevierStyleSectionTitle">Patients and methods</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">A retrospective review was made of the clinical histories of 147 previously healthy children, consecutively admitted to our hospital with ARTI for 1 year (May 1996-April 1997). Patients were divided in two groups: those not treated with antibiotics (n = 92) and those treated (n = 55). Data from the two groups were compared with a statistical computer program (R-Sigma)</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Of the 147 patients studied, mean age was 2.5 years (range 0-14 years) and 85 (58%) males. One-hundred-andfive patients (72%) had previously been attended to in the emergency room, and 45 patients (30%) had been treated with antibiotics. Upper respiratory tract infection was diagnosed in 81 patients (54%), bronchitis in 28 (18%), bronchiolitis in 23 (15%) and pneumonia in 15 (10%). Ninety- seven patients (66%) had viral infection and only two (1%) had bacterial infection. Syncytial respiratory virus was isolated in 41 patients (28%) and adenovirus in 30 (20%). In the untreated group, the longer duration of symptoms before admission, lymphocytosis, clinical diagnosis of bronchiolitis and normal thorax X-ray, were statistically significant. In the treated group, fever, leukocytosis, neutrophilia and a diagnosis of pneumonia were statistically significant. Length of stay was longer in this group than in the untreated group</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">It is difficult to prescribe antibiotics on the basis of bacteriologic data. Laboratory, analytic and radiological data can be helpful in the rational use of antibiotics</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografía" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:40 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1." 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| año/Mes | Html | Total | |
|---|---|---|---|
| 2024 Noviembre | 5 | 10 | 15 |
| 2024 Octubre | 42 | 55 | 97 |
| 2024 Septiembre | 58 | 39 | 97 |
| 2024 Agosto | 56 | 88 | 144 |
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| 2024 Junio | 39 | 33 | 72 |
| 2024 Mayo | 49 | 33 | 82 |
| 2024 Abril | 25 | 31 | 56 |
| 2024 Marzo | 36 | 36 | 72 |
| 2024 Febrero | 37 | 34 | 71 |
| 2024 Enero | 30 | 29 | 59 |
| 2023 Diciembre | 29 | 23 | 52 |
| 2023 Noviembre | 47 | 20 | 67 |
| 2023 Octubre | 36 | 23 | 59 |
| 2023 Septiembre | 36 | 23 | 59 |
| 2023 Agosto | 36 | 22 | 58 |
| 2023 Julio | 40 | 39 | 79 |
| 2023 Junio | 59 | 24 | 83 |
| 2023 Mayo | 53 | 29 | 82 |
| 2023 Abril | 42 | 18 | 60 |
| 2023 Marzo | 47 | 25 | 72 |
| 2023 Febrero | 33 | 22 | 55 |
| 2023 Enero | 10 | 33 | 43 |
| 2022 Diciembre | 24 | 27 | 51 |
| 2022 Noviembre | 47 | 34 | 81 |
| 2022 Octubre | 26 | 62 | 88 |
| 2022 Septiembre | 37 | 47 | 84 |
| 2022 Agosto | 30 | 58 | 88 |
| 2022 Julio | 22 | 54 | 76 |
| 2022 Junio | 35 | 37 | 72 |
| 2022 Mayo | 21 | 37 | 58 |
| 2022 Abril | 24 | 41 | 65 |
| 2022 Marzo | 29 | 59 | 88 |
| 2022 Febrero | 18 | 26 | 44 |
| 2022 Enero | 20 | 34 | 54 |
| 2021 Diciembre | 26 | 50 | 76 |
| 2021 Noviembre | 27 | 44 | 71 |
| 2021 Octubre | 42 | 53 | 95 |
| 2021 Septiembre | 21 | 46 | 67 |
| 2021 Agosto | 39 | 21 | 60 |
| 2021 Julio | 39 | 32 | 71 |
| 2021 Junio | 34 | 31 | 65 |
| 2021 Mayo | 17 | 26 | 43 |
| 2021 Abril | 77 | 89 | 166 |
| 2021 Marzo | 76 | 20 | 96 |
| 2021 Febrero | 44 | 26 | 70 |
| 2021 Enero | 52 | 25 | 77 |
| 2020 Diciembre | 46 | 17 | 63 |
| 2020 Noviembre | 17 | 13 | 30 |
| 2020 Octubre | 21 | 18 | 39 |
| 2020 Septiembre | 21 | 7 | 28 |
| 2020 Agosto | 22 | 3 | 25 |
| 2020 Julio | 20 | 12 | 32 |
| 2020 Junio | 26 | 7 | 33 |
| 2020 Mayo | 14 | 13 | 27 |
| 2020 Abril | 24 | 15 | 39 |
| 2020 Marzo | 18 | 13 | 31 |
| 2020 Febrero | 25 | 12 | 37 |
| 2020 Enero | 30 | 16 | 46 |
| 2019 Diciembre | 37 | 18 | 55 |
| 2019 Noviembre | 15 | 3 | 18 |
| 2019 Octubre | 20 | 16 | 36 |
| 2019 Septiembre | 19 | 18 | 37 |
| 2019 Agosto | 19 | 8 | 27 |
| 2019 Julio | 25 | 25 | 50 |
| 2019 Junio | 38 | 24 | 62 |
| 2019 Mayo | 40 | 54 | 94 |
| 2019 Abril | 30 | 37 | 67 |
| 2019 Marzo | 17 | 13 | 30 |
| 2019 Febrero | 17 | 7 | 24 |
| 2019 Enero | 14 | 18 | 32 |
| 2018 Diciembre | 20 | 14 | 34 |
| 2018 Noviembre | 20 | 12 | 32 |
| 2018 Octubre | 34 | 15 | 49 |
| 2018 Septiembre | 21 | 5 | 26 |
| 2018 Agosto | 1 | 0 | 1 |
| 2018 Julio | 1 | 0 | 1 |
| 2018 Mayo | 3 | 0 | 3 |
| 2018 Abril | 10 | 0 | 10 |
| 2018 Marzo | 7 | 0 | 7 |
| 2018 Febrero | 6 | 0 | 6 |
| 2018 Enero | 11 | 0 | 11 |
| 2017 Diciembre | 8 | 0 | 8 |
| 2017 Noviembre | 9 | 0 | 9 |
| 2017 Octubre | 5 | 0 | 5 |
| 2017 Septiembre | 9 | 0 | 9 |
| 2017 Agosto | 6 | 0 | 6 |
| 2017 Julio | 11 | 1 | 12 |
| 2017 Junio | 14 | 7 | 21 |
| 2017 Mayo | 16 | 11 | 27 |
| 2017 Abril | 14 | 11 | 25 |
| 2017 Marzo | 13 | 3 | 16 |
| 2017 Febrero | 8 | 5 | 13 |
| 2017 Enero | 6 | 3 | 9 |
| 2016 Diciembre | 26 | 10 | 36 |
| 2016 Noviembre | 38 | 5 | 43 |
| 2016 Octubre | 45 | 9 | 54 |
| 2016 Septiembre | 40 | 5 | 45 |
| 2016 Agosto | 26 | 5 | 31 |
| 2016 Julio | 21 | 5 | 26 |
| 2016 Febrero | 1 | 0 | 1 |
| 2015 Diciembre | 3 | 0 | 3 |
| 2015 Noviembre | 1 | 0 | 1 |
| 2015 Octubre | 1 | 0 | 1 |
| 2015 Septiembre | 1 | 0 | 1 |
| 2015 Julio | 13 | 0 | 13 |
| 2015 Junio | 6 | 0 | 6 |
| 2015 Mayo | 12 | 0 | 12 |
| 2015 Abril | 10 | 0 | 10 |
| 2015 Marzo | 6 | 0 | 6 |
| 2015 Febrero | 3 | 0 | 3 |
| 2015 Enero | 4 | 0 | 4 |
| 2014 Diciembre | 12 | 0 | 12 |
| 2014 Noviembre | 8 | 0 | 8 |
| 2014 Octubre | 13 | 0 | 13 |
| 2014 Septiembre | 7 | 0 | 7 |
| 2014 Agosto | 10 | 0 | 10 |
| 2014 Julio | 3 | 0 | 3 |
| 2014 Junio | 20 | 0 | 20 |
| 2014 Mayo | 9 | 0 | 9 |
| 2014 Abril | 13 | 0 | 13 |
| 2014 Marzo | 12 | 0 | 12 |
| 2014 Febrero | 9 | 0 | 9 |
| 2014 Enero | 11 | 0 | 11 |
| 2013 Diciembre | 17 | 0 | 17 |
| 2013 Noviembre | 11 | 0 | 11 |
| 2013 Octubre | 17 | 0 | 17 |
| 2013 Septiembre | 16 | 0 | 16 |
| 2013 Agosto | 21 | 0 | 21 |
| 2013 Julio | 4 | 0 | 4 |
| 2013 Junio | 1 | 0 | 1 |
| 2013 Mayo | 5 | 0 | 5 |
| 2013 Abril | 2 | 0 | 2 |
| 2013 Marzo | 2 | 0 | 2 |
| 2013 Febrero | 19 | 0 | 19 |
| 2013 Enero | 7 | 0 | 7 |
| 2012 Diciembre | 2 | 0 | 2 |
| 2012 Noviembre | 4 | 0 | 4 |
| 2012 Octubre | 2 | 0 | 2 |
| 2012 Septiembre | 4 | 0 | 4 |
| 2012 Agosto | 1 | 0 | 1 |
| 2012 Julio | 1 | 0 | 1 |
| 2000 Febrero | 2497 | 0 | 2497 |
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