Tratamiento con láser de las anomalías vasculares cutáneas en la infancia: análisis prospectivo en 95 niños
Treatment of cutaneous vascular lesions in infancy by the flashlamppumped pulsed dye laser: prospective analysis of our experience in 95 children
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Álvarez Martín, J.M. Merino Arribas, S. Ansó Oliván, R. Montero Alonso, M.T. Gil Rivas, J. Aldea Martínez, J. Sánchez Martín" "autores" => array:7 [ 0 => array:2 [ "nombre" => "T." "apellidos" => "Álvarez Martín" ] 1 => array:2 [ "nombre" => "J.M." "apellidos" => "Merino Arribas" ] 2 => array:2 [ "nombre" => "S." "apellidos" => "Ansó Oliván" ] 3 => array:2 [ "nombre" => "R." "apellidos" => "Montero Alonso" ] 4 => array:2 [ "nombre" => "M.T." "apellidos" => "Gil Rivas" ] 5 => array:2 [ "nombre" => "J." "apellidos" => "Aldea Martínez" ] 6 => array:2 [ "nombre" => "J." "apellidos" => "Sánchez Martín" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1695403300772845?idApp=UINPBA00005H" "url" => "/16954033/0000005200000001/v1_201307051856/S1695403300772845/v1_201307051856/es/main.assets" ] "itemAnterior" => array:18 [ "pii" => "S1695403300772821" "issn" => "16954033" "doi" => "10.1016/S1695-4033(00)77282-1" "estado" => "S300" "fechaPublicacion" => "2000-01-01" "aid" => "77282" "copyright" => "Asociación Española de Pediatría" "documento" => "article" "crossmark" => 0 "subdocumento" => "edi" "cita" => "An Pediatr (Barc). 2000;52:3-5" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 5775 "formatos" => array:3 [ "EPUB" => 89 "HTML" => 4749 "PDF" => 937 ] ] "es" => array:7 [ "idiomaDefecto" => true "titulo" => "Tratamiento de lesiones vasculares benignas con el láser de colorante pulsado a 585 nm" "tienePdf" => "es" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "3" "paginaFinal" => "5" ] ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "P. Boixeda de Miquel" "autores" => array:1 [ 0 => array:2 [ "nombre" => "P." "apellidos" => "Boixeda de Miquel" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1695403300772821?idApp=UINPBA00005H" "url" => "/16954033/0000005200000001/v1_201307051856/S1695403300772821/v1_201307051856/es/main.assets" ] "es" => array:14 [ "idiomaDefecto" => true "titulo" => "Tratamiento con láser de las anomalías vasculares cutáneas en la infancia: análisis prospectivo en 95 niños" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "6" "paginaFinal" => "14" ] ] "autores" => array:2 [ 0 => array:4 [ "autoresLista" => "M. Asín Llorca, M.R. Navarro Belmonte" "autores" => array:2 [ 0 => array:3 [ "nombre" => "M." "apellidos" => "Asín Llorca" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:2 [ "nombre" => "M.R." "apellidos" => "Navarro Belmonte" ] ] "afiliaciones" => array:1 [ 0 => array:1 [ "entidad" => "Centro Clínico Dermatológico. Alicante" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "*" "correspondencia" => "Centro Clínico Dermatológico. Pintor Velázquez, 58. 03004 Alicante." ] ] ] 1 => array:3 [ "autoresLista" => "J. González de Dios" "autores" => array:1 [ 0 => array:3 [ "nombre" => "J." "apellidos" => "González de Dios" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "aff0005" ] ] ] ] "afiliaciones" => array:1 [ 0 => array:3 [ "entidad" => "Departamento de Pediatría. Hospital Universitario San Juan. Universidad Miguel Hernández. Alicante" "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "aff0005" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Treatment of cutaneous vascular lesions in infancy by the flashlamppumped pulsed dye laser: prospective analysis of our experience in 95 children" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "1999-02-28" "fechaAceptado" => "1999-08-31" "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec187619" "palabras" => array:3 [ 0 => "Láser" 1 => "Nevus flammeus" 2 => "Hemangiomas" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec187620" "palabras" => array:4 [ 0 => "Laser" 1 => "Children" 2 => "Nevus flammeus" 3 => "Hemangiomas" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Fundamento</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">El uso del láser de colorante a impulsos por lámpara de destellos ha mejorado los resultados en el tratamiento de las anomalías vasculares cutáneas, dado que actúa de forma más específica sobre los vasos que otros tipos de láser (argón Nd:Yag). El objetivo de este artículo es analizar nuestra experiencia en el tratamiento de las anomalías vasculares cutáneas de la infancia con este tipo de láser.</p> <span class="elsevierStyleSectionTitle">Material y métodos</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">El estudio comprende a 95 pacientes de edad igual o inferior a 18 años con anomalías vasculares cutáneas (85 con <span class="elsevierStyleItalic">nevus flammeus</span> y 10 con hemangiomas) que fueron tratados con láser de colorante a impulsos por lámpara de destellos. Los pacientes reciben tratamiento hasta que se aclara la lesión vascular, o bien se suspende cuando no existe una respuesta adecuada. Se analizaron prospectivamente todos los pacientes durante el tratamiento, con el fin de valorar la evolución clínica y la incidencia de efectos secundarios.</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">El estudio engloba a 54 niñas y 41 niños, con un intervalo de edad que oscila entre los 3 meses y los 18 años, con una edad media de 7,3 ± 5,2 años. Sólo 6 niños fueron tratados con menos de 6 meses de edad. Las lesiones vasculares se encontraban localizadas en 78 casos en la cara, en nueve en el cuello, en ocho en las extremidades, en cinco en el tronco y en dos en otras regiones (área perianal y cuero cabelludo). El número de sesiones de tratamiento necesarias para la resolución de la anomalía vascular (en 52 <span class="elsevierStyleItalic">nevus flammeus</span> y en 10 hemangiomas en el momento del estudio) fue de 9,8 ± 7,5 (intervalo, 1–36), con variaciones en relación con el tipo de anomalía vascular (más sesiones en los <span class="elsevierStyleItalic">nevus flammeus</span> que en los hemangiomas) y su localización anatómica (mayor número de sesiones en la cara y menor en espalda, brazo y labios). Los efectos secundarios del láser fueron leves y transitorios.</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">El láser es una modalidad de tratamiento útil y segura en el tratamiento de las anomalías vasculares cutáneas en la infancia. Los principales factores determinantes de la respuesta al tratamiento son el tipo de anomalía vascular y la localización, así como el tamaño de la lesión y la edad del paciente.</p>" ] "en" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Background</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Recently the flashlamp-pumped dye laser has improved treatment of cutaneous vascular lesions results since this laser acts much more vessel specific than other laser (argon, Nd:Yag). The objective of this manuscript is to analyze our experience in the treatment of vascular lesions in infancy with the pulsed dye laser.</p> <span class="elsevierStyleSectionTitle">Material and methods</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Ninety-five patients ≤ 18 years with vascular lesions (85 <span class="elsevierStyleItalic">nevus flammeus</span> and 10 hemangiomas) were treated prospectively with the flashlamp-pumped dye laser. The patients received therapy until the lesion was almost clear, or until the lesion failed to respond. All patients were examined during the course of their treatment to assess the clinical evolution and the incidence of adverse effects associated with the use of the laser.</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">The study consisted of 54 females and 41 males ranged in age from 3 months to 18 years, with the average age being 7.3 ± 5.2 years. Only six children were treated with less than six months of age. Seventy-eight vascular lesions were located on the face, nine on the neck, eight on the extremities, five on the trunk, and two on other regions (perineal area and scalp). The number of treatment sessions needed for the resolution of the cutaneous vascular lesion (in 52 nevus flammeus and 10 hemangiomas, at the moment) was 9.8 ± 7.5 (range 1 to 36), with variations in relation to the type of vascular lesion (more sessions in nevus flammeus than hemangiomas) and their anatomical location (more sessions in the face and less in shoulder, arms and lips). The adverse effects were slights and transitories.</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Laser therapy is useful and safe in the treatment of cutaneous vascular lesions in infancy. 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| año/Mes | Html | Total | |
|---|---|---|---|
| 2024 Noviembre | 6 | 14 | 20 |
| 2024 Octubre | 36 | 33 | 69 |
| 2024 Septiembre | 35 | 38 | 73 |
| 2024 Agosto | 43 | 83 | 126 |
| 2024 Julio | 36 | 41 | 77 |
| 2024 Junio | 42 | 32 | 74 |
| 2024 Mayo | 40 | 37 | 77 |
| 2024 Abril | 36 | 48 | 84 |
| 2024 Marzo | 24 | 42 | 66 |
| 2024 Febrero | 31 | 53 | 84 |
| 2024 Enero | 32 | 40 | 72 |
| 2023 Diciembre | 19 | 24 | 43 |
| 2023 Noviembre | 32 | 26 | 58 |
| 2023 Octubre | 28 | 20 | 48 |
| 2023 Septiembre | 23 | 29 | 52 |
| 2023 Agosto | 24 | 32 | 56 |
| 2023 Julio | 34 | 51 | 85 |
| 2023 Junio | 26 | 34 | 60 |
| 2023 Mayo | 39 | 37 | 76 |
| 2023 Abril | 26 | 24 | 50 |
| 2023 Marzo | 24 | 50 | 74 |
| 2023 Febrero | 23 | 10 | 33 |
| 2023 Enero | 17 | 17 | 34 |
| 2022 Diciembre | 38 | 21 | 59 |
| 2022 Noviembre | 30 | 38 | 68 |
| 2022 Octubre | 28 | 60 | 88 |
| 2022 Septiembre | 31 | 38 | 69 |
| 2022 Agosto | 37 | 66 | 103 |
| 2022 Julio | 23 | 48 | 71 |
| 2022 Junio | 31 | 45 | 76 |
| 2022 Mayo | 24 | 60 | 84 |
| 2022 Abril | 32 | 69 | 101 |
| 2022 Marzo | 37 | 56 | 93 |
| 2022 Febrero | 30 | 33 | 63 |
| 2022 Enero | 23 | 59 | 82 |
| 2021 Diciembre | 26 | 73 | 99 |
| 2021 Noviembre | 28 | 55 | 83 |
| 2021 Octubre | 43 | 65 | 108 |
| 2021 Septiembre | 22 | 55 | 77 |
| 2021 Agosto | 31 | 37 | 68 |
| 2021 Julio | 32 | 45 | 77 |
| 2021 Junio | 20 | 63 | 83 |
| 2021 Mayo | 25 | 51 | 76 |
| 2021 Abril | 54 | 55 | 109 |
| 2021 Marzo | 54 | 15 | 69 |
| 2021 Febrero | 92 | 22 | 114 |
| 2021 Enero | 63 | 33 | 96 |
| 2020 Diciembre | 43 | 34 | 77 |
| 2020 Noviembre | 25 | 10 | 35 |
| 2020 Octubre | 30 | 5 | 35 |
| 2020 Septiembre | 22 | 5 | 27 |
| 2020 Agosto | 27 | 11 | 38 |
| 2020 Julio | 25 | 11 | 36 |
| 2020 Junio | 22 | 17 | 39 |
| 2020 Mayo | 42 | 24 | 66 |
| 2020 Abril | 29 | 11 | 40 |
| 2020 Marzo | 34 | 14 | 48 |
| 2020 Febrero | 21 | 13 | 34 |
| 2020 Enero | 41 | 28 | 69 |
| 2019 Diciembre | 68 | 37 | 105 |
| 2019 Noviembre | 22 | 19 | 41 |
| 2019 Octubre | 6 | 42 | 48 |
| 2019 Septiembre | 29 | 36 | 65 |
| 2019 Agosto | 27 | 13 | 40 |
| 2019 Julio | 17 | 29 | 46 |
| 2019 Junio | 27 | 34 | 61 |
| 2019 Mayo | 31 | 86 | 117 |
| 2019 Abril | 23 | 50 | 73 |
| 2019 Marzo | 24 | 29 | 53 |
| 2019 Febrero | 16 | 9 | 25 |
| 2019 Enero | 19 | 14 | 33 |
| 2018 Diciembre | 22 | 25 | 47 |
| 2018 Noviembre | 22 | 43 | 65 |
| 2018 Octubre | 41 | 23 | 64 |
| 2018 Septiembre | 19 | 10 | 29 |
| 2018 Agosto | 1 | 0 | 1 |
| 2018 Julio | 1 | 0 | 1 |
| 2018 Junio | 2 | 0 | 2 |
| 2018 Mayo | 2 | 0 | 2 |
| 2018 Abril | 8 | 0 | 8 |
| 2018 Marzo | 7 | 0 | 7 |
| 2018 Febrero | 7 | 1 | 8 |
| 2018 Enero | 3 | 0 | 3 |
| 2017 Diciembre | 8 | 0 | 8 |
| 2017 Noviembre | 13 | 0 | 13 |
| 2017 Octubre | 7 | 0 | 7 |
| 2017 Septiembre | 8 | 0 | 8 |
| 2017 Agosto | 10 | 0 | 10 |
| 2017 Julio | 8 | 3 | 11 |
| 2017 Junio | 17 | 38 | 55 |
| 2017 Mayo | 15 | 24 | 39 |
| 2017 Abril | 12 | 20 | 32 |
| 2017 Marzo | 12 | 22 | 34 |
| 2017 Febrero | 6 | 26 | 32 |
| 2017 Enero | 9 | 7 | 16 |
| 2016 Diciembre | 17 | 18 | 35 |
| 2016 Noviembre | 34 | 17 | 51 |
| 2016 Octubre | 32 | 17 | 49 |
| 2016 Septiembre | 35 | 13 | 48 |
| 2016 Agosto | 32 | 14 | 46 |
| 2016 Julio | 13 | 8 | 21 |
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