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Vol. 55. Issue 6.
Pages 503-510 (1 December 2001)
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Vol. 55. Issue 6.
Pages 503-510 (1 December 2001)
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Utilización de la alternancia de antipiréticos en el tratamiento de la fiebre en España
Use of alternating antipyretics in the treatment of fever in Spain
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12493
J. Díez Domingoa,
Corresponding author
diez_jav@gva.es

Correspondencia: Dr. J. Díez Domingo.Centro de Salud de Nazaret. Parque, 7B. 46024 Valencia.
, A. Burgos Ramírezb, J. Garrido Garcíab, A. Ballester Sanza, E. Moreno Carreterob
a Centro de Salud de Nazaret.
b Departamento Médico. Laboratorios Knoll. Madrid.
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Objetivo

Analizar la frecuencia de utilización de la administración alternante de antitérmicos entre los pediatras españoles, y los factores que determinan este uso.

Métodos

Se llevó a cabo una encuesta anónima a pediatras en ejercicio activo. Se recogieron los datos de utilización de antitérmicos. Se realizó un análisis de los factores relacionados con la alternancia de antipiréticos con técnicas multivariantes.

Resultados

Se obtuvieron 324 encuestas. La edad media de los participantes fue de 46,4 6 18,6 años (29-68 años de edad). El 22,5 % de los pediatras ejercían en un hospital, el 87,5% en un centro de salud y el 24,7 % tenía su consulta privada. El 68,8 % (IC 95 %, 63,4-73,8 %) utilizaban la pauta alternante de antipiréticos, siendo la combinación de ibuprofeno y paracetamol la recomendada por el 96,9 %. Se relaciona con la utilización secuencial de antitérmicos el hecho de ser varón (OR, 0,535; IC 95 %, 0,296-0,967; p 5 0,038), con pocos años de experiencia (OR, 0,952; IC 95 %, 0,922-0,984; p 5 0,005), considerar el ibuprofeno como fármaco de primera elección (OR, 2,324; IC 95 %, 1,235-4,372; p 5 0,009) y recomendar una nueva dosis de antitérmico ante leves ascensos de temperatura (OR, 0,529; IC 95 %, 0,310-0,901; p 5 0,019).

Conclusiones

A pesar de la falta de evidencia científica que lo justifique, la utilización combinada de antitérmicos es una pauta habitual de tratamiento de la fiebre infantil, siendo factores que predisponen a esta práctica que el pediatra sea varón y con pocos años de ejercicio, que el fármaco utilizado de entrada sea el ibuprofeno, y que se recomiende la utilización de antitérmicos para el tratamiento de fiebre de leve intensidad.

Palabras clave:
Antipiréticos
Utilización alternante
Fiebre
Niños
Objective

To assess the frequency of the use of alternating antipyretics among Spanish pediatricians and to analyze the factors that determine this practice.

Methods

An anonymous survey of practicing pediatricians was conducted. Data on the use of antipyretics were collected Factors related to alternating antipyretics were assessed by using multivariate correlation analyses.

Results

Three hundred twenty-four questionnaires were reviewed. The mean age of participants was 46.4 6 18.6 years (29-68 years). Of the responding pediatricians, 22.5 % worked in hospitals, 87.5 % in health centres and 24.7 % in in private practice. A total of 68.8 % of pediatricians (95 % CI: 63.4-73.8 %) alternated antipyretics. The combination of ibuprofen and acetaminophen was recommended by 96.9%. The use of alternating antipyretics was positively associated with male sex (OR: 0.535; 95% CI: 0.296-0.967; p 5 0.038), with few years experience (OR: 0.952; 95 % CI: 0.922-0.984, p 5 0.005), with considering ibuprofen the drug of choice (OR: 2.324; 95 % CI: 1.235-4.372; p 5 0.009) and with the doctor's recommendation that the antipyretic be readministered in the event of slight increases in temperature (OR: 0.529; 95 % CI:0.310-0.901; p 5 0.019).

Conclusions

Despite the lack of scientific evidence to justify the practice, the use of alternating antipyretics is common in the treatment of febrile children. Predictive factors of this practice among pediatricians are male sex, having relatively little experience, considering ibuprofen as the drug of choice and recommending the administration of new doses of antipyretic to control mild fever.

Key words:
Antipyretics
Alternating doses
Fever
Children
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Este estudio ha sido financiado por Laboratorios Knoll, S.A., Madrid, España

Copyright © 2001. Asociación Española de Pediatría
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