Images in Paediatrics
Lipomatosis epidural secundaria a corticoterapia
Epidural lipomatosis secondary to corticotherapy
Read
1815
Timeswas read the article
664
Total PDF
1151
Total HTML
Share statistics
array:24 [ "pii" => "S2341287923000728" "issn" => "23412879" "doi" => "10.1016/j.anpede.2022.11.006" "estado" => "S300" "fechaPublicacion" => "2023-05-01" "aid" => "3375" "copyright" => "Asociación Española de Pediatría" "copyrightAnyo" => "2022" "documento" => "article" "crossmark" => 1 "subdocumento" => "sco" "cita" => "An Pediatr (Barc). 2023;98:397-8" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "Traduccion" => array:1 [ "es" => array:19 [ "pii" => "S1695403322002570" "issn" => "16954033" "doi" => "10.1016/j.anpedi.2022.11.001" "estado" => "S300" "fechaPublicacion" => "2023-05-01" "aid" => "3375" "copyright" => "Asociación Española de Pediatría" "documento" => "article" "crossmark" => 1 "subdocumento" => "sco" "cita" => "An Pediatr (Barc). 2023;98:397-8" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "es" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">IMÁGENES EN PEDIATRÍA</span>" "titulo" => "Lipomatosis epidural secundaria a corticoterapia" "tienePdf" => "es" "tieneTextoCompleto" => "es" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "397" "paginaFinal" => "398" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Epidural lipomatosis secondary to corticotherapy" ] ] "contieneTextoCompleto" => array:1 [ "es" => true ] "contienePdf" => array:1 [ "es" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figura 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 755 "Ancho" => 1207 "Tamanyo" => 75711 ] ] "descripcion" => array:1 [ "es" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Resonancia magnética de columna que muestra aumento de la grasa epidural (lipomatosis epidural) que condiciona una estenosis del canal raquídeo dorsal (1A) y lumbar (1B). Mayor compromiso de espacio en el segmento L4-S1 (1B), con posible componente asociado de estenosis congénita del canal lumbar.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Marina Mora Sitja, Jorge Huerta Aragonés, María Sanz Fernández, Carmen Garrido Colino" "autores" => array:4 [ 0 => array:2 [ "nombre" => "Marina" "apellidos" => "Mora Sitja" ] 1 => array:2 [ "nombre" => "Jorge" "apellidos" => "Huerta Aragonés" ] 2 => array:2 [ "nombre" => "María" "apellidos" => "Sanz Fernández" ] 3 => array:2 [ "nombre" => "Carmen" "apellidos" => "Garrido Colino" ] ] ] ] ] "idiomaDefecto" => "es" "Traduccion" => array:1 [ "en" => array:9 [ "pii" => "S2341287923000728" "doi" => "10.1016/j.anpede.2022.11.006" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2341287923000728?idApp=UINPBA00005H" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1695403322002570?idApp=UINPBA00005H" "url" => "/16954033/0000009800000005/v1_202305032020/S1695403322002570/v1_202305032020/es/main.assets" ] ] "itemSiguiente" => array:19 [ "pii" => "S2341287923000704" "issn" => "23412879" "doi" => "10.1016/j.anpede.2023.03.002" "estado" => "S300" "fechaPublicacion" => "2023-05-01" "aid" => "3353" "copyright" => "Asociación Española de Pediatría" "documento" => "article" "crossmark" => 1 "subdocumento" => "sco" "cita" => "An Pediatr (Barc). 2023;98:399-400" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Images in Paediatrics</span>" "titulo" => "Brown spots on the tongue" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "399" "paginaFinal" => "400" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Lesiones marrones en la lengua" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:8 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 525 "Ancho" => 1340 "Tamanyo" => 104265 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0005" "detalle" => "Figure " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">A. Multiples brown fungiform papules located in the tip of the tongue. B. Detail.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Diego Soto-García, Carmen Couselo-Rodríguez, Sandra Martínez-Fernández, Ángeles Flórez" "autores" => array:4 [ 0 => array:2 [ "nombre" => "Diego" "apellidos" => "Soto-García" ] 1 => array:2 [ "nombre" => "Carmen" "apellidos" => "Couselo-Rodríguez" ] 2 => array:2 [ "nombre" => "Sandra" "apellidos" => "Martínez-Fernández" ] 3 => array:2 [ "nombre" => "Ángeles" "apellidos" => "Flórez" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S169540332200217X" "doi" => "10.1016/j.anpedi.2022.09.014" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S169540332200217X?idApp=UINPBA00005H" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2341287923000704?idApp=UINPBA00005H" "url" => "/23412879/0000009800000005/v1_202305080100/S2341287923000704/v1_202305080100/en/main.assets" ] "itemAnterior" => array:19 [ "pii" => "S2341287923000777" "issn" => "23412879" "doi" => "10.1016/j.anpede.2023.03.004" "estado" => "S300" "fechaPublicacion" => "2023-05-01" "aid" => "3355" "copyright" => "Asociación Española de Pediatría" "documento" => "article" "crossmark" => 1 "subdocumento" => "sco" "cita" => "An Pediatr (Barc). 2023;98:395-6" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Images in Paediatrics</span>" "titulo" => "Rapidly involuting congenital hemangioma in a newborn" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "395" "paginaFinal" => "396" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Hemangioma congénito rápidamente involutivo en recién nacido" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:8 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1096 "Ancho" => 1005 "Tamanyo" => 87043 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0005" "detalle" => "Figure " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Involution of congenital hemangioma at birth.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Mireia Vallés Arenes, Altea Esteve Martínez, José Ángel García García, María Teresa Guixeres Esteve" "autores" => array:4 [ 0 => array:2 [ "nombre" => "Mireia" "apellidos" => "Vallés Arenes" ] 1 => array:2 [ "nombre" => "Altea" "apellidos" => "Esteve Martínez" ] 2 => array:2 [ "nombre" => "José Ángel" "apellidos" => "García García" ] 3 => array:2 [ "nombre" => "María Teresa" "apellidos" => "Guixeres Esteve" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S1695403322002193" "doi" => "10.1016/j.anpedi.2022.09.016" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1695403322002193?idApp=UINPBA00005H" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2341287923000777?idApp=UINPBA00005H" "url" => "/23412879/0000009800000005/v1_202305080100/S2341287923000777/v1_202305080100/en/main.assets" ] "en" => array:16 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Images in Paediatrics</span>" "titulo" => "Lipomatosis epidural secundaria a corticoterapia" "tieneTextoCompleto" => true "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "397" "paginaFinal" => "398" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Marina Mora Sitja, Jorge Huerta Aragonés, María Sanz Fernández, Carmen Garrido Colino" "autores" => array:4 [ 0 => array:4 [ "nombre" => "Marina" "apellidos" => "Mora Sitja" "email" => array:1 [ 0 => "marina.mora@salud.madrid.org" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "Jorge" "apellidos" => "Huerta Aragonés" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 2 => array:3 [ "nombre" => "María" "apellidos" => "Sanz Fernández" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 3 => array:3 [ "nombre" => "Carmen" "apellidos" => "Garrido Colino" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Sección Endocrinología Pediátrica, Hospital General Universitario Gregorio Marañón, Madrid, Spain" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Sección Hematología y Oncología Hospital General Universitario Gregorio Marañón, Madrid, Spain" "etiqueta" => "b" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Epidural lipomatosis secondary to corticotherapy" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:8 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 755 "Ancho" => 1207 "Tamanyo" => 74042 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0005" "detalle" => "Figure " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Magnetic resonance of the spine evincing an increase in epidural fat (spinal epidural lipomatosis) resulting in stenosis of the spinal canal at the dorsal (1A) and lumbar (1B) levels. The mass effect was most severe in the L4-S1 segment (1B) and possibly compounded by congenital lumbar canal stenosis.</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">A male patient aged 15 years who had received a diagnosis of Evans syndrome required prolonged treatment with prednisone (2<span class="elsevierStyleHsp" style=""></span>mg/kg/day for 4 weeks, followed by a dose of 1<span class="elsevierStyleHsp" style=""></span>mg/kg day that could not be reduced due to recurrence). At 3 months of treatment, he started experiencing intense, activity-limiting lumbar pain unresponsive to analgesia, progressive, radiating from the lower extremities and decreased proximal strength (4/5). The patient was admitted for evaluation and pain management. A magnetic resonance imaging (MRI) scan of the spine evinced extensive spinal epidural lipomatosis (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>) secondary to the treatment.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0010" class="elsevierStylePara elsevierViewall">Conservative treatment with analgesia and rehabilitation was initiated at the same time as mycophenolate mofetil for treatment of Evans syndrome with the aim of tapering off the steroid, which was withdrawn completely 3 months after the diagnosis of lipomatosis without any complications. The patient had a favourable outcome.</p><p id="par0015" class="elsevierStylePara elsevierViewall">Spinal epidural lipomatosis is characterised by an overgrowth of fatty tissue in the epidural sac in the spinal canal that can cause progressive compression of the spinal cord. Steroid therapy has been described as its most common cause<a class="elsevierStyleCrossRefs" href="#bib0005"><span class="elsevierStyleSup">1,2</span></a>, and while spinal epidural lipomatosis is a rare adverse event, it should be suspected in patients presenting with compatible symptoms compatibles (lumbar pain, pain and loss of strength in lower extremities). Magnetic resonance is the gold standard of diagnosis<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a> and the first-line treatment is conservative—with some patients requiring surgical decompression<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a>—with withdrawal of the steroid whenever possible.</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Funding</span><p id="par0020" class="elsevierStylePara elsevierViewall">This research did not receive any external funding.</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Conflicts of interest</span><p id="par0025" class="elsevierStylePara elsevierViewall">The authors have no conflicts of interest to declare.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:3 [ 0 => array:2 [ "identificador" => "sec0005" "titulo" => "Funding" ] 1 => array:2 [ "identificador" => "sec0010" "titulo" => "Conflicts of interest" ] 2 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2022-08-12" "fechaAceptado" => "2022-11-02" "multimedia" => array:1 [ 0 => array:8 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 755 "Ancho" => 1207 "Tamanyo" => 74042 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0005" "detalle" => "Figure " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Magnetic resonance of the spine evincing an increase in epidural fat (spinal epidural lipomatosis) resulting in stenosis of the spinal canal at the dorsal (1A) and lumbar (1B) levels. The mass effect was most severe in the L4-S1 segment (1B) and possibly compounded by congenital lumbar canal stenosis.</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:3 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Corticosteroid-induced spinal epidural lipomatosis in the pediatric age group: report of a new case and updated analysis of the literature" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "J.C. Möller" 1 => "R.Q. Cron" 2 => "D.W. Young" 3 => "H.J. Girschick" 4 => "D.M. Levy" 5 => "D.D. Sherry" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1186/1546-0096-9-5" "Revista" => array:5 [ "tituloSerie" => "Pediatr Rheumatol Online J" "fecha" => "2011" "volumen" => "9" "paginaInicial" => "5" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21284882" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Spinal Epidural Lipomatosis: A Comprehensive Review" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "P.B. Walker" 1 => "C. Sark" 2 => "G. Brennan" 3 => "T. Smith" 4 => "W.F. Sherman" 5 => "A.D. Kaye" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.52965/001c.25571" "Revista" => array:5 [ "tituloSerie" => "Orthop Rev (Pavia)" "fecha" => "2021" "volumen" => "13" "paginaInicial" => "25571" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/34745483" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0015" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Symptomatic epidural lipomatosis of the spinal cord in a child: MR demonstration of spinal cord injury" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "A. Muñoz" 1 => "J.A. Barkovich" 2 => "F. Mateos" 3 => "R. Simón" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Pediatr Radiol" "fecha" => "2002" "volumen" => "32" "paginaInicial" => "865" "paginaFinal" => "868" ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/23412879/0000009800000005/v1_202305080100/S2341287923000728/v1_202305080100/en/main.assets" "Apartado" => array:4 [ "identificador" => "77701" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Images in Paediatrics" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/23412879/0000009800000005/v1_202305080100/S2341287923000728/v1_202305080100/en/main.pdf?idApp=UINPBA00005H&text.app=https://analesdepediatria.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2341287923000728?idApp=UINPBA00005H" ]
| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 9 | 6 | 15 |
| 2024 October | 46 | 34 | 80 |
| 2024 September | 64 | 35 | 99 |
| 2024 August | 60 | 49 | 109 |
| 2024 July | 38 | 43 | 81 |
| 2024 June | 62 | 30 | 92 |
| 2024 May | 59 | 27 | 86 |
| 2024 April | 50 | 38 | 88 |
| 2024 March | 53 | 31 | 84 |
| 2024 February | 38 | 38 | 76 |
| 2024 January | 61 | 29 | 90 |
| 2023 December | 76 | 23 | 99 |
| 2023 November | 61 | 55 | 116 |
| 2023 October | 73 | 47 | 120 |
| 2023 September | 79 | 40 | 119 |
| 2023 August | 62 | 32 | 94 |
| 2023 July | 61 | 23 | 84 |
| 2023 June | 67 | 29 | 96 |
| 2023 May | 132 | 55 | 187 |
Show all
