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        "resumen" => "<span class="elsevierStyleSectionTitle">Introducci&#243;n</span><p class="elsevierStyleSimplePara elsevierViewall">El citomegalovirus &#40;CMV&#41; es el agente etiol&#243;gico m&#225;s com&#250;n asociado a infecci&#243;n perinatal&#46; La incidencia de esta afecci&#243;n neonatal es m&#225;s elevada en pa&#237;ses con nivel socioecon&#243;mico bajo&#46; La seroprevalencia del CMV en las embarazadas paname&#241;as y la incidencia de la infecci&#243;n cong&#233;nita son desconocidas&#44; son tambi&#233;n escasos los informes al respecto publicados en Latinoam&#233;rica&#46;</p> <span class="elsevierStyleSectionTitle">Objetivo</span><p class="elsevierStyleSimplePara elsevierViewall">El objetivo de este estudio es determinar la seroprevalencia de la infecci&#243;n por CMV en pu&#233;rperas y la potencial morbilidad en los hijos de madres seropositivas&#46;</p> <span class="elsevierStyleSectionTitle">Pacientes y m&#233;todos</span><p class="elsevierStyleSimplePara elsevierViewall">Se tomaron 316 muestras de sangre a mujeres pu&#233;rperas para determinaci&#243;n de inmunoglobulina G &#40;IgG&#41; para CMV y 317 muestras de orina a sus neonatos para prueba de reacci&#243;n en cadena de la polimerasa &#40;PCR&#41; para CMV&#46; Adem&#225;s se analizaron presuntos factores de riesgo tales como paridad&#44; nivel socioecon&#243;mico y nivel educativo&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">Se encontr&#243; una seroprevalencia de CMV 84 &#37; y una incidencia de 0&#44;8 &#37; de CMV cong&#233;nito en mujeres seropositivas&#46; Se diagnosticaron 2 casos de infecci&#243;n cong&#233;nita por CMV&#44; uno de los cuales present&#243; signos cl&#237;nicos al nacimiento&#44; pero ninguno de ellos present&#243; secuelas auditivas o en el neurodesarrollo en sus primeros 11 meses de vida&#46; No se document&#243; asociaci&#243;n de serolog&#237;a positiva con la paridad&#44; nivel socioecon&#243;mico ni educaci&#243;n de la madre&#46;</p> <span class="elsevierStyleSectionTitle">Conclusi&#243;n</span><p class="elsevierStyleSimplePara elsevierViewall">Aunque ninguno de los ni&#241;os diagnosticados con infecci&#243;n cong&#233;nita por CMV en nuestro estudio present&#243; secuelas de la misma al momento de este informe&#44; consideramos que la incidencia de infecci&#243;n cong&#233;nita encontrada de 0&#44;8 &#37; debe ser tomada en cuenta para evaluar la posibilidad de incluir las pruebas diagn&#243;sticas para CMV dentro del tamizaje neonatal e implementar medidas educativas para evitar la exposici&#243;n a posibles fuentes de este virus en madres seronegativas&#46;</p>"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Introduction</span><p class="elsevierStyleSimplePara elsevierViewall">Cytomegalovirus &#40;CMV&#41; is the most frequent etiologic agent associated with perinatal infections&#46; The incidence of this infection is higher in developing countries&#46; The seroprevalence of CMV infection among pregnant women and its impact on newborns have not been studied in Panama and there are a few publications on this health problem in Latin America&#46;</p> <span class="elsevierStyleSectionTitle">Objective</span><p class="elsevierStyleSimplePara elsevierViewall">The purpose of this study was to determine the seroprevalence of CMV infection in puerperal women and CMV-related morbidity in the neonates of seropositive mothers&#46;</p> <span class="elsevierStyleSectionTitle">Patients and methods</span><p class="elsevierStyleSimplePara elsevierViewall">A total of 316 blood samples from puerperal women and 317 urine samples from their newborns were obtained to determine CMV IgG and the polymerase chain reaction CMV test respectively&#46; Risk factors such as parity&#44; socioeconomic status and educational level were analyzed&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">The seroprevalence of CMV was 84 &#37; and the incidence of congenital CMV infection in the newborns of seropositive women was 0&#46;8&#37;&#46; Two cases of congenital CMV infection were diagnosed&#44; one of which showed clinical signs at birth&#44; but neither of the newborns showed neurological or audiological sequels in the first 11 months of life&#46; There were no correlations between positive serology and parity&#44; socioeconomic status or educational level in the mothers studied&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">Although neither of the newborns diagnosed with congenital CMV infection showed clinical signs at the time of this report&#44; we believe that the incidence of 0&#46;8&#37; found in this study should be kept in mind with a view to evaluating the possibility of including CMV diagnostic tests in neonatal screening and introducing measures to prevent seronegative mothers from becoming infected&#46;</p>"
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Seroprevalencia de la infección por citomegalovirus en puérperas y su impacto neonatal
Seroprevalence of cytomegalovirus infection in puerperal women and its impact on their newborns
D. Estripeauta,
Corresponding author
destripeaut@yahoo.com

Correspondencia: Dra. D. Estripeaut. Servicio de Infectología. Hospital del Niño. Av. Balboa, 34. Panamá.
, Y. Morenob, S. Ahumada Ruizc, A. Martínezc, J.D. Racined, X. Sáez-Llorensa
a Servicio de Infectología. Hospital del Niño
b Servicio de Pediatría. Hospital del Niño
c Instituto de Investigaciones Científicas Avanzadas y Servicios de Alta Tecnología
d Laboratorio Clínico. Hospital del Niño. Panamá
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        "titulo" => "Seroprevalence of cytomegalovirus infection in puerperal women and its impact on their newborns"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Introducci&#243;n</span><p class="elsevierStyleSimplePara elsevierViewall">El citomegalovirus &#40;CMV&#41; es el agente etiol&#243;gico m&#225;s com&#250;n asociado a infecci&#243;n perinatal&#46; La incidencia de esta afecci&#243;n neonatal es m&#225;s elevada en pa&#237;ses con nivel socioecon&#243;mico bajo&#46; La seroprevalencia del CMV en las embarazadas paname&#241;as y la incidencia de la infecci&#243;n cong&#233;nita son desconocidas&#44; son tambi&#233;n escasos los informes al respecto publicados en Latinoam&#233;rica&#46;</p> <span class="elsevierStyleSectionTitle">Objetivo</span><p class="elsevierStyleSimplePara elsevierViewall">El objetivo de este estudio es determinar la seroprevalencia de la infecci&#243;n por CMV en pu&#233;rperas y la potencial morbilidad en los hijos de madres seropositivas&#46;</p> <span class="elsevierStyleSectionTitle">Pacientes y m&#233;todos</span><p class="elsevierStyleSimplePara elsevierViewall">Se tomaron 316 muestras de sangre a mujeres pu&#233;rperas para determinaci&#243;n de inmunoglobulina G &#40;IgG&#41; para CMV y 317 muestras de orina a sus neonatos para prueba de reacci&#243;n en cadena de la polimerasa &#40;PCR&#41; para CMV&#46; Adem&#225;s se analizaron presuntos factores de riesgo tales como paridad&#44; nivel socioecon&#243;mico y nivel educativo&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">Se encontr&#243; una seroprevalencia de CMV 84 &#37; y una incidencia de 0&#44;8 &#37; de CMV cong&#233;nito en mujeres seropositivas&#46; Se diagnosticaron 2 casos de infecci&#243;n cong&#233;nita por CMV&#44; uno de los cuales present&#243; signos cl&#237;nicos al nacimiento&#44; pero ninguno de ellos present&#243; secuelas auditivas o en el neurodesarrollo en sus primeros 11 meses de vida&#46; No se document&#243; asociaci&#243;n de serolog&#237;a positiva con la paridad&#44; nivel socioecon&#243;mico ni educaci&#243;n de la madre&#46;</p> <span class="elsevierStyleSectionTitle">Conclusi&#243;n</span><p class="elsevierStyleSimplePara elsevierViewall">Aunque ninguno de los ni&#241;os diagnosticados con infecci&#243;n cong&#233;nita por CMV en nuestro estudio present&#243; secuelas de la misma al momento de este informe&#44; consideramos que la incidencia de infecci&#243;n cong&#233;nita encontrada de 0&#44;8 &#37; debe ser tomada en cuenta para evaluar la posibilidad de incluir las pruebas diagn&#243;sticas para CMV dentro del tamizaje neonatal e implementar medidas educativas para evitar la exposici&#243;n a posibles fuentes de este virus en madres seronegativas&#46;</p>"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Introduction</span><p class="elsevierStyleSimplePara elsevierViewall">Cytomegalovirus &#40;CMV&#41; is the most frequent etiologic agent associated with perinatal infections&#46; The incidence of this infection is higher in developing countries&#46; The seroprevalence of CMV infection among pregnant women and its impact on newborns have not been studied in Panama and there are a few publications on this health problem in Latin America&#46;</p> <span class="elsevierStyleSectionTitle">Objective</span><p class="elsevierStyleSimplePara elsevierViewall">The purpose of this study was to determine the seroprevalence of CMV infection in puerperal women and CMV-related morbidity in the neonates of seropositive mothers&#46;</p> <span class="elsevierStyleSectionTitle">Patients and methods</span><p class="elsevierStyleSimplePara elsevierViewall">A total of 316 blood samples from puerperal women and 317 urine samples from their newborns were obtained to determine CMV IgG and the polymerase chain reaction CMV test respectively&#46; Risk factors such as parity&#44; socioeconomic status and educational level were analyzed&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">The seroprevalence of CMV was 84 &#37; and the incidence of congenital CMV infection in the newborns of seropositive women was 0&#46;8&#37;&#46; Two cases of congenital CMV infection were diagnosed&#44; one of which showed clinical signs at birth&#44; but neither of the newborns showed neurological or audiological sequels in the first 11 months of life&#46; There were no correlations between positive serology and parity&#44; socioeconomic status or educational level in the mothers studied&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">Although neither of the newborns diagnosed with congenital CMV infection showed clinical signs at the time of this report&#44; we believe that the incidence of 0&#46;8&#37; found in this study should be kept in mind with a view to evaluating the possibility of including CMV diagnostic tests in neonatal screening and introducing measures to prevent seronegative mothers from becoming infected&#46;</p>"
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Article information
ISSN: 16954033
Original language: Spanish
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Idiomas
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