A case of undifferentiated embryonic liver sarcoma mimicking cystic hydatid disease in an endemic region of the world☆
Section snippets
Case report
A 7-year-old man was admitted to our hospital emergency department with acute abdominal pain. A physical examination revealed abdominal tenderness localized in the right upper quadrant, nausea, and vomiting. Laboratory studies showed normal serum bilirubin levels and mildly elevated aspartate aminotransferase (42 UI/L), alkaline phosphates (72 UI/L), and glutamic-pyruvic transaminase (53 UI/L) serum levels. Abdominal US showed a 6 × 5 cm cystic lesion with septation and echogenic material in
Discussion
Malignant primary hepatic tumors make up approximately 1% of pediatric tumors in the US [17]. Hepatoblastoma (HB) and hepatocellular carcinoma (HCC) are, by far, the most common malignant primary hepatic tumors in childhood [11]. Sarcomas are the third most common malignant primary hepatic tumors, comprising approximately 6% of hepatic malignancies in childhood [18]. For example, Moore et al [8] reported 194 cases of malignant primary hepatic tumors in children. Of these patients, 58% had HB,
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Cited by (8)
Multi-disciplinary treatment of undifferentiated embryonal sarcoma of the liver with tumor embolus extending to the heart
2021, Journal of Pediatric Surgery Case ReportsCitation Excerpt :The origin of the tumor and histopathological findings were consistent with the diagnosis of UESL (PRETEXTIII, E0, F0, H0, M0, N1, P0, V3) [3]. Although right pleural effusion with negative cytology required continuous drainage and hindered prompt chemotherapeutic intervention, we administered VDC-IE regimen (vincristine (VCR), 1.5 mg/m2 on days 1 and 8; doxorubicin, 37.5 mg/m2 on days 1 and 2; cyclophosphamide (CPM), 600 mg/m2 on days 1 and 2; ifosfamide, 1.8 g/m2 on days 15–19 and etoposide, 100 mg/m2 on days 15–19) starting on day 4 after biopsy [4], which did not affect. We next administered intensified VAC (VCR, 1.5 mg/m2; actinomycin D, 0.045 mg/kg; and CPM, 2.2 g/m2) [5], which also had no effect.
Diagnosis and management of hydatid liver disease in children: A report of 156 patients with hydatid disease
2012, Journal of Pediatric SurgeryCitation Excerpt :The imaging methods used for diagnosis was US, plain chest roentgenograms, and CT with contrast in all patients. We misdiagnosed only 1 patient with an undifferentiated embryonic liver sarcoma [21]. Our experience and that of Turkyilmaz et al [12] suggest that other diagnostic tests such as magnetic resonance imaging and scintigraphy or invasive studies such as angiography are not necessary in regions where the disease is endemic.
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2020, Chronic Disease and Disability: The Pediatric LiverUndifferentiated embryonal sarcoma of the liver with an unusual presentation: Case report and review of the literature
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None of the authors has a commercial interest, financial interest, and/or other relationship with manufacturers of pharmaceuticals, laboratory supplies, and/or medical devices or with commercial providers of medically related services.