Original articleSacrococcygeal teratoma—a 25-year experience in a UK regional center
Section snippets
Patients and methods
The neonatal surgery database and regional tumor registry were accessed to identify all patients with SCT treated at the Royal Liverpool Children's Hospital (Alder Hey) between 1977 and 2001 inclusive. Patient demographics including antenatal details, mode of delivery, age at presentation, sex, associated anomalies, and tumor histology were recorded. Surgical management with respect to resection of the primary tumor, and early and late postoperative complications were noted. Outcomes relating
Results
Thirty-three patients with a diagnosis of SCT were treated during the study period. There were 28 females and 5 males. Before 1988, only 2 (11%) of 18 patients had tumors diagnosed by antenatal ultrasonography compared with 8 of 15 (53%) in the years 1988 to 2001. Average birth weight was 3.3 kg (range, 1.5-4.9 kg) and mean age at delivery was 37 weeks (range, 30-41 weeks). Ten babies were delivered by cesarean birth for obstetric and/or fetal indications. Seven (21%) patients presented after
Discussion
We report one of the largest SCT series from a single European center. Data from this 25-year study confirm a female predominance, incidence of associated anomalies, and typical presentation of “monstrous” neonatal lesions [1], [4], [9]. Before the late 1980s, while detection of fetal SCT was low (11%), it is of interest that neonatal morbidity was not encountered from unplanned vaginal delivery. Antenatal diagnosis was achieved in more than 50% of the patient population from 1988 to 2001 [2],
Acknowledgments
The authors thank past and present colleagues in medical oncology, radiology, pediatric surgery, and urology for their skill, support, and contribution to patient care. We also acknowledge the professional cooperation of Mr Steve Walkinshaw and Professor Zarco Alfiveric at the Fetal Treatment Centre, Liverpool Women's Hospital.
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Long-term functional outcomes of sacrococcygeal teratoma – A systematic review of published studies exploring ‘real world’ outcomes
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2019, Journal of Pediatric SurgeryLong-Term Outcome of Sacrococcygeal Teratoma: A Controlled Cohort Study of Urinary Tract and Bowel Dysfunction and Predictors of Poor Outcome
2018, Journal of PediatricsCitation Excerpt :Previous studies have shown a substantial heterogeneity in the frequency of urinary tract and bowel dysfunction following surgical excision of sacrococcygeal teratoma.9-19 Problems with respect to bladder voiding dysfunction, straining, incontinence, enuresis, and neurogenic bladder have been reported in 7%-55%.9-19 Our study showed urinary tract dysfunction in 29% of the children with sacrococcygeal teratoma, which is comparable with the observations in 1 of the largest studies, of 79 children with sacrococcygeal teratoma, which reported 31% with urinary incontinence.10
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2024, Child's Nervous System
This work was presented at the Joint Meeting of The International Society of Paediatric Oncology (SIOP XXXV) and the International Society of Pediatric Surgical Oncology (IPSO XXXV), Cairo, Egypt, October 8 to 11, 2003, and published as abstract O026 in the conference proceedings [Med Pediatr Oncol 2003;41(4): 263-4].