The Journal of Allergy and Clinical Immunology: In Practice
Clinical CommunicationSuccessful rapid tocilizumab desensitization in a patient with Still disease
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Anaphylaxis to Drugs, Biological Agents, and Vaccines
2022, Immunology and Allergy Clinics of North AmericaCitation Excerpt :For patients in whom an IgE-mediated reaction is suspected, desensitization can be performed. 116Immediate HSRs related to other commonly prescribed biologics are summarized in Table 5.73,98,117–121 The risk of anaphylaxis after any vaccine is rare: 1.31 per million vaccine doses.122
Rapid desensitisation to tocilizumab in systemic idiopathic juvenile arthritis
2021, Anales de PediatriaPractical Guidance for the Evaluation and Management of Drug Hypersensitivity: Specific Drugs
2020, Journal of Allergy and Clinical Immunology: In PracticeCitation Excerpt :It is used to treat rheumatoid arthritis and systemic or polyarticular juvenile arthritis.501 Immediate hypersensitivity reactions to tocilizumab are rare, but several cases of anaphylaxis have been reported occurring from the second exposure onward.502,503 Skin testing (Table LVIII) is usually useful in identifying patients with an IgE-mediated hypersensitivity reaction, and desensitization (Table LIX) should be considered the method of choice to reexpose those patients to tocilizumab (Figure 6).470,474,502,503
Hypersensitivity Reactions to Monoclonal Antibodies
2018, Drug Allergy TestingMonoclonal Antibodies Hypersensitivity: Prevalence and Management
2017, Immunology and Allergy Clinics of North America
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Conflicts of interest: The authors declare that they have no relevant conflicts of interest.