Case reportAbortive or minimal-growth hemangiomas: Immunohistochemical evidence that they represent true infantile hemangiomas
Section snippets
Methods
We included patients seen between January and December 2006 with lesions resembling precursor lesions of hemangiomas that did not show proliferation after the first few months of life. We describe the clinical features and evolution. In all cases we performed a punch biopsy of the lesions for histologic study and GLUT-1 antibody staining (DAKO Corp, Carpinteria, Calif) (dilution 1/100).
Results
Three of our patients (patients 1, 2, and 4) presented with reticulated erythematous patches with multiple fine telangiectases over pale-pink or normal-appearing skin. Patient 3 presented with a flat bluish macule with some telangiectasia and a white peripheral halo. All were present at birth (Table I). We have not observed, nor did the parents report, any further growth.
We also observed two histologic patterns, one pattern with ectatic vessels in the papillary dermis and the other with a few
Discussion
In this article, we are describing a peculiar presentation of IH. They are present at birth and, therefore, congenital, although we have avoided using this term to avoid confusion with NICH or rapidly involuting congenital hemangioma, which are clinically and histologically distinct.10, 11, 12, 13 They appear as reticulated erythematous patches (pseudocapillary malformations) with multiple fine telangiectasia on the surface; grouped telangiectases overlying normal-appearing skin; or bluish
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2020, JAAD Case ReportsCitation Excerpt :Infantile hemangioma with minimal or arrested growth is considered a subtype of infantile hemangioma because Corella et al1 confirmed the expression of glucose transporter protein-1 on these vascular lesions.
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2016, Anales de PediatriaReticular infantile hemangiomas with minimal or arrested growth associated with lipoatrophy
2015, Journal of the American Academy of DermatologyCitation Excerpt :Although a coincidence could not be excluded, such an association raised the question of a mild variant of this syndrome, even though the developmental anomalies were located anatomically far from the RIH-MAG. The co-occurrence of IH and lipoatrophy is rarely mentioned in the literature and, to our knowledge, no IH-MAG, reticular or otherwise, associated with lipoatrophy has been reported in sizable case series.3,5-7,9 There are 2 previous potential observations of RIH-MAG overlying segmental lipoatrophy.
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2015, Handbook of Clinical NeurologyCitation Excerpt :Within weeks, erythematous papules and plaques develop confirming the hemangioma diagnosis. In some instances the hemangioma fails to proliferate and maintains a reticular or telangiectatic appearance (Corella et al., 2008). The infantile hemangioma also differs from the facial birthmarks associated with Wyburn-Mason syndrome, which represents a quiescent Schobinger type-1 arteriovenous malformation, and the capillary malformation–AVM syndrome (Theron et al., 1974; Garzon et al., 2007).
Funding sources: None.
Conflicts of interest: None declared.