Epidemiology of Celiac Disease

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Key points

  • Celiac disease (CD) is a common chronic condition in many parts of the world.

  • CD affects people of all ages, with a slight predisposition for women.

  • The cause of CD requires both genetic and environmental factors, primarily and essentially the human leukocyte antigen types DQ2 or DQ8 and intake of gluten.

  • CD has a broad range of presenting symptoms and syndromes that make detection challenging, with many patients remaining undiagnosed for long periods.

  • Diagnosis relies on serology tests, although

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      Citation Excerpt :

      Its prevalence is increasing [1]. A recent meta-analysis study of epidemiologic surveys showed an estimated seroprevalence of 1.4% and biopsy-proven prevalence of 0.7% [2]. Increased incidences occurred globally, even in traditionally low incidence geographic regions such as Asia [3].

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    Disclosure: All authors have completed the ICMJE uniform disclosure form at www.icmje.org/coi_disclosure.pdf and declare that this project was supported by grants from the Swedish Society of Medicine and the Stockholm County Council, and the Swedish Research Council (grant 2013-2429).

    Disclaimer: This article represents the views of the authors. The authors have nothing else to disclose.

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