CardiomyopathyUsefulness of Arrhythmias as Predictors of Death and Resource Utilization in Children With Myocarditis
Section snippets
Methods
A retrospective cohort study was performed, using the Pediatric Health Information System (PHIS) database, to determine if the presence of arrhythmias was associated with in-hospital mortality, length of stay, and costs per day for children admitted with acute myocarditis. This study was classified by the Columbia University Medical Center Institutional Review Board as nonhuman subjects research and was exempted from further review.
Data for this study were obtained from PHIS, an administrative
Results
A total of 2,041 children from 44 hospitals were identified with acute myocarditis during the study period. The distribution of age was bimodal, with 1/4 of patients admitted at <1 year of age (25.6% [n = 522]) and slightly more than 1/4 admitted at >15 years of age (27.8% [n = 568]) (see Figure 1). Congenital heart disease was reported in 132 subjects (6.4%). Viral infection was indicated in 284 subjects (13.9%). The most frequently reported viruses were influenza, rhinovirus, and parvovirus,
Discussion
In this multicenter, retrospective database study, the presence of a clinically significant tachyarrhythmia was associated with increased in-hospital mortality, length of stay, and costs per day for children admitted with acute myocarditis. No associations were detected between the presence of bradyarrhythmias and the measured outcomes, after controlling for significant confounders.
Despite the significant morbidity and mortality that can be associated with pediatric myocarditis, limited data
Disclosures
The authors have no conflicts of interest to disclose.
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