TY - JOUR T1 - Experience in food protein-induced enterocolitis syndrome in a paediatric allergy clinic JO - Anales de Pediatría (English Edition) T2 - AU - Pérez Ajami,Rasha Isabel AU - Carrión Sari,Silvia Karina AU - Aliaga Mazas,Yolanda AU - Calvo,Javier Boné AU - Guallar Abadía,María Isabel SN - 23412879 M3 - 10.1016/j.anpede.2019.09.007 DO - 10.1016/j.anpede.2019.09.007 UR - https://analesdepediatria.org/en-experience-in-food-protein-induced-enterocolitis-articulo-S2341287920300697 AB - IntroductionFood protein-induced enterocolitis syndrome (FPIES) is a gastrointestinal syndrome due to a non-IgE mediated food hypersensitivity. The most common triggers are cow's milk and soy. Fish is one of the most frequently reported causes in Spain.The objective of this study is to describe the clinical characteristics of patients diagnosed with (FPIES) in a paediatric allergy clinic. Material and methodsA retrospective descriptive study was carried out by reviewing medical records of patients diagnosed with FPIES in the Paediatric Allergy Unit of the Miguel Servet Children's Hospital from the years 2007 to 2017. ResultsA total of 135 patients were diagnosed during the study period, of whom 45% were male and 55% were female. The mean age at diagnosis was 11±1.5 months and the mean age of improvement was 2 years and 6 months±2.5 years (n=83). A personal history of atopy was observed in 31.9%. The main trigger foods were: white fish (41.4%), cow's milk (25.1%), and egg (15.5%). A conversion to IgE-mediated allergy was seen in 4.4% of patients.There was vomiting in 81.5% of the cases, with a mean of 1.75±1.1h of latency, as well as diarrhoea in 41.5%, with a mean of 7.86±15.16h of latency, and decline in 30.4% with a mean latency of 3.81±11.57h. DiscussionIn our series, the most frequent trigger of the FPIES was fish. It was manifested mainly by late vomiting and a tolerance was reached mostly at 2 years 6 months. ER -