TY - JOUR T1 - A comparison of post-surgical plasma glucose levels in patients on fluids with different glucose concentrations JO - Anales de Pediatría (English Edition) T2 - AU - Martínez Carapeto,Isabel AU - López Castilla,José Domingo AU - Fresneda Gutiérrez,Reyes SN - 23412879 M3 - 10.1016/j.anpede.2017.10.003 DO - 10.1016/j.anpede.2017.10.003 UR - https://analesdepediatria.org/en-a-comparison-post-surgical-plasma-glucose-articulo-S2341287918301261 AB - ObjectiveTo compare plasma glucose levels and incidence of hyperglycaemia in the post-operative period after general surgery using fluids with different glucose. MethodologyA randomised, open-label, non-blind, clinical trial was conducted on patients admitted to Paediatric Intensive Care Unit after elective surgery. The inclusion criteria were from 6 months to 14 years of age, with a weight greater than 6kg, onset glucose level >60mg/dL, and a signed informed consent, with no oral intake and maintenance intravenous fluid therapy using fluids with 3.3% or 5% glucose. Plasma glucose levels were measured before surgery, on admission, and 8, 24, and 48h, with the mean glucose levels and incidence of hyperglycaemia (glucose level >150mg/dL) in both groups being compared. ResultsA total of 60 patients received glucose/saline 1/3 (51mEq/L sodium and 33g/L glucose), and 70 glucose/saline 5/0.9% (154mEq/L sodium and 50g/L glucose). Mean glucose levels were higher in the group receiving glucose 5%, with no statistical difference. There was no significant difference in the incidence of hyperglycaemia; 8h: 26% in the 3.3% group vs. 21.3% in the 5% group (P=.63); 24h: 20% vs. 22.7% (P=.8); and 48h: 19% vs. 23.1% (P=.78). ConclusionsThe use of fluids with 3.3% glucose in the post-operative period of general surgery maintains mean glucose levels in a similar range to that of patients receiving fluids with 5% glucose, with no difference in the incidence of hyperglycaemia. ER -