TY - JOUR T1 - Five steps to decreasing nosocomial infections in very preterm newborns: A quasi-experimental study JO - Anales de Pediatría (English Edition) T2 - AU - García González,Ana AU - Leante Castellanos,José Luis AU - Fuentes Gutiérrez,Carmen AU - Lloreda García,José María AU - Fernández Fructuoso,José Ramón AU - Gómez Santos,Elisabet AU - García González,Verónica SN - 23412879 M3 - 10.1016/j.anpede.2016.06.009 DO - 10.1016/j.anpede.2016.06.009 UR - https://analesdepediatria.org/en-five-steps-decreasing-nosocomial-infections-articulo-S2341287917300984 AB - ObjectivesAn evaluation is made of the impact of a series of five interventions on the incidence of hospital-related infections in a level iii neonatal unit. Material and methodsQuasi-experimental, pre-post intervention study, which included preterm infants weighing 1500g at birth or delivered at <32 weeks gestation, admitted in the 12 months before and after the measures were implemented (January 2014). The measures consisted of: optimising hand washing, following a protocol for insertion and handling of central intravenous catheters, encouraging breastfeeding; applying a protocol for rational antibiotic use, and establishing a surveillance system for multi-resistant bacteria. The primary endpoint was to assess the incidence of hospital-acquired infections before and after implementing the interventions. ResultsThirty-three matched patients were included in each period. There was an incidence of 8.7 and 2.7 hospital-related infections/1000 hospital stay days in the pre- and post-intervention periods, respectively (P<.05). Additionally, patients in the treatment group showed a statistically-significant decrease in days on mechanical ventilation, use of blood products, and vasoactive drugs. ConclusionsThe strategy, based on implementing five specific measures in a unit with a high rate of hospital-related infections, proved effective in reducing their incidence. This reduction could contribute to lowering the use of mechanical ventilation, blood products, and vasoactive drugs. ER -